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• W2155233750 abstract "Approximately 20%-30% of patients with acute promyelocytic leukemia (APL) who are treated with the current standard all-trans retinoic acid and anthracycline-based chemotherapy regimen suffer relapse. In the mid-1990s, studies from China reported the effective use of arsenic trioxide in achieving complete remission in patients with APL. In the United States, a multicenter trial of this agent in 40 patients with relapsed APL following conventional therapy confirmed the positive safety and efficacy outcomes of a smaller 12-patient pilot study. Common adverse events were hyperleukocytosis, APL differentiation syndrome, prolonged QT interval on electrocardiogram, skin rash, and hyperglycemia." @default.
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• W2155233750 date "2001-04-01" @default.
• W2155233750 modified "2023-10-03" @default.
• W2155233750 title "Risk/Benefit Profile of Arsenic Trioxide" @default.
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• W2155233750 doi "https://doi.org/10.1634/theoncologist.6-suppl_2-29" @default.
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