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- W2155286540 abstract "Host-range variants of mouse mammary tumour viruses (MMTVs) have previously been shown to productively infect cells of several species in vitro (Howard & Schlom, 1978). We report here that cell lines have been identified which exhibit differential restriction for replication of different MMTV variants. In addition, a cell line has been identified that changes as a function of passage in culture from being permissive to being restrictive to infection with MMTVs. MMTVs propagated in both murine and non-murine cells retained their antigenic reactivities in a group-specific radioimmunoassay for MMTVs and demonstrated no evidence for the presence of type-C viruses as determined by a variety of techniques. These studies thus establish in vitro cell substrate tropisms that can be used to differentiate between MMTVs." @default.
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- W2155286540 date "1980-04-01" @default.
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- W2155286540 title "Differential Host Ranges for in vitro Infectivity of Mouse Mammary Tumour Viruses" @default.
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- W2155286540 doi "https://doi.org/10.1099/0022-1317-47-2-439" @default.
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