FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155287121> ?p ?o ?g. }

• W2155287121 endingPage "3129" @default.
• W2155287121 startingPage "3115" @default.
• W2155287121 abstract "Single-strand break repair (SSBR) and base excision repair (BER) of modified bases and abasic sites share several players. Among them is XRCC1, an essential scaffold protein with no enzymatic activity, required for the coordination of both pathways. XRCC1 is recruited to SSBR by PARP-1, responsible for the initial recognition of the break. The recruitment of XRCC1 to BER is still poorly understood. Here we show by using both local and global induction of oxidative DNA base damage that XRCC1 participation in BER complexes can be distinguished from that in SSBR by several criteria. We show first that XRCC1 recruitment to BER is independent of PARP. Second, unlike SSBR complexes that are assembled within minutes after global damage induction, XRCC1 is detected later in BER patches, with kinetics consistent with the repair of oxidized bases. Third, while XRCC1-containing foci associated with SSBR are formed both in eu- and heterochromatin domains, BER complexes are assembled in patches that are essentially excluded from heterochromatin and where the oxidized bases are detected." @default.
• W2155287121 created "2016-06-24" @default.
• W2155287121 creator A5025865841 @default.
• W2155287121 creator A5039440705 @default.
• W2155287121 creator A5060629623 @default.
• W2155287121 creator A5065375123 @default.
• W2155287121 creator A5076300458 @default.
• W2155287121 creator A5077371245 @default.
• W2155287121 date "2013-01-25" @default.
• W2155287121 modified "2023-10-04" @default.
• W2155287121 title "Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair" @default.
• W2155287121 cites W1587686680 @default.
• W2155287121 cites W1912177776 @default.
• W2155287121 cites W1956982520 @default.
• W2155287121 cites W1967894483 @default.
• W2155287121 cites W1969175894 @default.
• W2155287121 cites W1971297671 @default.
• W2155287121 cites W1971577441 @default.
• W2155287121 cites W1972363323 @default.
• W2155287121 cites W1973050277 @default.
• W2155287121 cites W1978122209 @default.
• W2155287121 cites W1983898731 @default.
• W2155287121 cites W1984598028 @default.
• W2155287121 cites W1989006164 @default.
• W2155287121 cites W1989456683 @default.
• W2155287121 cites W1989540020 @default.
• W2155287121 cites W1993046370 @default.
• W2155287121 cites W1999541392 @default.
• W2155287121 cites W2003657279 @default.
• W2155287121 cites W2004864721 @default.
• W2155287121 cites W2028392042 @default.
• W2155287121 cites W2029065442 @default.
• W2155287121 cites W2033172828 @default.
• W2155287121 cites W2034844603 @default.
• W2155287121 cites W2037867164 @default.
• W2155287121 cites W2038204769 @default.
• W2155287121 cites W2041815718 @default.
• W2155287121 cites W2043943343 @default.
• W2155287121 cites W2064426325 @default.
• W2155287121 cites W2065107886 @default.
• W2155287121 cites W2068073395 @default.
• W2155287121 cites W2068533511 @default.
• W2155287121 cites W2070660722 @default.
• W2155287121 cites W2072528578 @default.
• W2155287121 cites W2073046245 @default.
• W2155287121 cites W2082919291 @default.
• W2155287121 cites W2092793423 @default.
• W2155287121 cites W2092845419 @default.
• W2155287121 cites W2099077495 @default.
• W2155287121 cites W2100675082 @default.
• W2155287121 cites W2100730597 @default.
• W2155287121 cites W2111511350 @default.
• W2155287121 cites W2114280096 @default.
• W2155287121 cites W2116094026 @default.
• W2155287121 cites W2117662983 @default.
• W2155287121 cites W2118211359 @default.
• W2155287121 cites W2121909403 @default.
• W2155287121 cites W2124733101 @default.
• W2155287121 cites W2125782175 @default.
• W2155287121 cites W2131415510 @default.
• W2155287121 cites W2132396299 @default.
• W2155287121 cites W2161489869 @default.
• W2155287121 cites W2165432409 @default.
• W2155287121 cites W2168891239 @default.
• W2155287121 cites W4240436575 @default.
• W2155287121 cites W4247607816 @default.
• W2155287121 doi "https://doi.org/10.1093/nar/gkt025" @default.
• W2155287121 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3597691" @default.
• W2155287121 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23355608" @default.
• W2155287121 hasPublicationYear "2013" @default.
• W2155287121 type Work @default.
• W2155287121 sameAs 2155287121 @default.
• W2155287121 citedByCount "89" @default.
• W2155287121 countsByYear W21552871212013 @default.
• W2155287121 countsByYear W21552871212014 @default.
• W2155287121 countsByYear W21552871212015 @default.
• W2155287121 countsByYear W21552871212016 @default.
• W2155287121 countsByYear W21552871212017 @default.
• W2155287121 countsByYear W21552871212018 @default.
• W2155287121 countsByYear W21552871212019 @default.
• W2155287121 countsByYear W21552871212020 @default.
• W2155287121 countsByYear W21552871212021 @default.
• W2155287121 countsByYear W21552871212022 @default.
• W2155287121 countsByYear W21552871212023 @default.
• W2155287121 crossrefType "journal-article" @default.
• W2155287121 hasAuthorship W2155287121A5025865841 @default.
• W2155287121 hasAuthorship W2155287121A5039440705 @default.
• W2155287121 hasAuthorship W2155287121A5060629623 @default.
• W2155287121 hasAuthorship W2155287121A5065375123 @default.
• W2155287121 hasAuthorship W2155287121A5076300458 @default.
• W2155287121 hasAuthorship W2155287121A5077371245 @default.
• W2155287121 hasBestOaLocation W21552871211 @default.
• W2155287121 hasConcept C103435993 @default.
• W2155287121 hasConcept C104317684 @default.
• W2155287121 hasConcept C134935766 @default.
• W2155287121 hasConcept C135763542 @default.
• W2155287121 hasConcept C143425029 @default.
• W2155287121 hasConcept C153209595 @default.

• next