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• W2155339227 abstract "Nearly 1 in 20 patients receiving cancer-directed surgery for the most common or deadly cancers die within 1 month of the procedure, with unmarried, uninsured, non-white, male, older, less educated, and poorer patients at a higher risk for 1-month mortality. Reduction of 1-month surgical mortality and sociodemographic disparities thereof may improve survival among patients with cancer.BackgroundDeath within 1 month of surgery is considered treatment related and serves as an important health care quality metric. We sought to identify the incidence of and factors associated with 1-month mortality after cancer-directed surgery.Patients and methodsWe used the Surveillance, Epidemiology and End Results Program to study a cohort of 1 110 236 patients diagnosed from 2004 to 2011 with cancers that are among the 10 most common or most fatal who received cancer-directed surgery. Multivariable logistic regression analyses were used to identify factors associated with 1-month mortality after cancer-directed surgery.ResultsA total of 53 498 patients (4.8%) died within 1 month of cancer-directed surgery. Patients who were married, insured, or who had a top 50th percentile income or educational status had lower odds of 1-month mortality from cancer-directed surgery {[adjusted odds ratio (AOR) 0.80; 95% confidence interval (CI) 0.79–0.82; P < 0.001], (AOR 0.88; 95% CI 0.82–0.94; P < 0.001), (AOR 0.95; 95% CI 0.93–0.97; P < 0.001), and (AOR 0.98; 95% CI 0.96–0.99; P = 0.043), respectively}. Patients who were non-white minority, male, or older (per year increase), or who had advanced tumor stage 4 disease all had a higher risk of 1-month mortality after cancer-directed surgery, with AORs of 1.13 (95% CI 1.11–1.15), P < 0.001; 1.11 (95% CI 1.08–1.13), P < 0.001; 1.02 (95% 1.02–1.03), P < 0.001; and 1.89 (95% CI 1.82–1.95), P < 0.001 respectively.ConclusionsUnmarried, uninsured, non-white, male, older, less educated, and poorer patients were all at a significantly higher risk for death within 1 month of cancer-directed surgery. Efforts to reduce 1-month surgical mortality and eliminate sociodemographic disparities in this adverse outcome could significantly improve survival among patients with cancer." @default.
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• W2155339227 date "2015-02-01" @default.
• W2155339227 modified "2023-10-10" @default.
• W2155339227 title "Incidence and determinants of 1-month mortality after cancer-directed surgery" @default.
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• W2155339227 doi "https://doi.org/10.1093/annonc/mdu534" @default.
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