FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155358348> ?p ?o ?g. }

• W2155358348 endingPage "93" @default.
• W2155358348 startingPage "86" @default.
• W2155358348 abstract "PROBLEM: The uterine milk proteins (UTMP) are a pair of related glycoproteins that are the major secretory products of the endometrium of the pregnant ewe. UTMP are members of the serpin superfamily of serine protease inhibitors but have no known antiprotease activity. One possible role for UTMP is to inhibit uterine immune responses—UTMP inhibit mitogen and mixed lymphocyte-induced proliferation of peripheral blood lymphocytes, natural killer (NK) cell activity and abortion caused by NK cell activation. Present objectives were to further evaluate the lymphocyte-inhibitory activity of UTMP and test whether UTMP modify immune responses in vivo. METHOD: One experiment demonstrated that UTMP inhibited antigen-induced lymphocyte proliferation induced by Candida albicans extract. In another experiment, ewes were immunized with OVA mixed with 3.75 mg/ml of UTMP or ovine serum albumin (OSA control). Injections of 1 mg OVA + UTMP or OSA in incomplete adjuvant were administered 6 wk later. Titers of antibody to OVA were lower (P<0.001) for ewes administered UTMP than for ewes administered OSA. Effects of UTMP on delayed hypersensitivity reactions were evaluated in three experiments using skin-fold thickness assays. RESULTS: UTMP did not inhibit the increase in skin-fold thickness caused by PHA and Mycobacterium tuberculosis but rather tended to increase the response to PHA. CONCLUSION: Results strengthen the thesis that UTMP are physiologically relevant immunoregulatory molecules. Nonetheless, effects on skin-fold responses indicate that actions of UTMP can be more complex than would be predicted based on the proteins only having a single biological effect." @default.
• W2155358348 created "2016-06-24" @default.
• W2155358348 creator A5027878420 @default.
• W2155358348 creator A5028606515 @default.
• W2155358348 creator A5038776482 @default.
• W2155358348 date "1995-01-01" @default.
• W2155358348 modified "2023-10-12" @default.
• W2155358348 title "Effects of Endometrial Serpin-Like Proteins on Immune Responses in Sheep" @default.
• W2155358348 cites W1488554402 @default.
• W2155358348 cites W1496911446 @default.
• W2155358348 cites W1501423905 @default.
• W2155358348 cites W1509731141 @default.
• W2155358348 cites W1597278646 @default.
• W2155358348 cites W1638514368 @default.
• W2155358348 cites W1967476376 @default.
• W2155358348 cites W1968841296 @default.
• W2155358348 cites W1987433281 @default.
• W2155358348 cites W1993448456 @default.
• W2155358348 cites W2001570522 @default.
• W2155358348 cites W2002736874 @default.
• W2155358348 cites W2007935706 @default.
• W2155358348 cites W2012430497 @default.
• W2155358348 cites W2017377818 @default.
• W2155358348 cites W2023965197 @default.
• W2155358348 cites W2024654467 @default.
• W2155358348 cites W2034858770 @default.
• W2155358348 cites W2040982787 @default.
• W2155358348 cites W2042288334 @default.
• W2155358348 cites W2073745965 @default.
• W2155358348 cites W2078753269 @default.
• W2155358348 cites W2112137224 @default.
• W2155358348 cites W2117862502 @default.
• W2155358348 cites W2127319519 @default.
• W2155358348 cites W2129480210 @default.
• W2155358348 cites W2158324523 @default.
• W2155358348 cites W2160881967 @default.
• W2155358348 cites W2161735767 @default.
• W2155358348 cites W2415905290 @default.
• W2155358348 cites W2539722741 @default.
• W2155358348 doi "https://doi.org/10.1111/j.1600-0897.1995.tb01143.x" @default.
• W2155358348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7619239" @default.
• W2155358348 hasPublicationYear "1995" @default.
• W2155358348 type Work @default.
• W2155358348 sameAs 2155358348 @default.
• W2155358348 citedByCount "23" @default.
• W2155358348 countsByYear W21553583482013 @default.
• W2155358348 countsByYear W21553583482015 @default.
• W2155358348 countsByYear W21553583482016 @default.
• W2155358348 crossrefType "journal-article" @default.
• W2155358348 hasAuthorship W2155358348A5027878420 @default.
• W2155358348 hasAuthorship W2155358348A5028606515 @default.
• W2155358348 hasAuthorship W2155358348A5038776482 @default.
• W2155358348 hasConcept C104317684 @default.
• W2155358348 hasConcept C134018914 @default.
• W2155358348 hasConcept C147483822 @default.
• W2155358348 hasConcept C150903083 @default.
• W2155358348 hasConcept C159654299 @default.
• W2155358348 hasConcept C203014093 @default.
• W2155358348 hasConcept C207001950 @default.
• W2155358348 hasConcept C2776946954 @default.
• W2155358348 hasConcept C2777761686 @default.
• W2155358348 hasConcept C2777863537 @default.
• W2155358348 hasConcept C2778965386 @default.
• W2155358348 hasConcept C55493867 @default.
• W2155358348 hasConcept C86803240 @default.
• W2155358348 hasConcept C8891405 @default.
• W2155358348 hasConceptScore W2155358348C104317684 @default.
• W2155358348 hasConceptScore W2155358348C134018914 @default.
• W2155358348 hasConceptScore W2155358348C147483822 @default.
• W2155358348 hasConceptScore W2155358348C150903083 @default.
• W2155358348 hasConceptScore W2155358348C159654299 @default.
• W2155358348 hasConceptScore W2155358348C203014093 @default.
• W2155358348 hasConceptScore W2155358348C207001950 @default.
• W2155358348 hasConceptScore W2155358348C2776946954 @default.
• W2155358348 hasConceptScore W2155358348C2777761686 @default.
• W2155358348 hasConceptScore W2155358348C2777863537 @default.
• W2155358348 hasConceptScore W2155358348C2778965386 @default.
• W2155358348 hasConceptScore W2155358348C55493867 @default.
• W2155358348 hasConceptScore W2155358348C86803240 @default.
• W2155358348 hasConceptScore W2155358348C8891405 @default.
• W2155358348 hasIssue "1" @default.
• W2155358348 hasLocation W21553583481 @default.
• W2155358348 hasLocation W21553583482 @default.
• W2155358348 hasOpenAccess W2155358348 @default.
• W2155358348 hasPrimaryLocation W21553583481 @default.
• W2155358348 hasRelatedWork W1973161539 @default.
• W2155358348 hasRelatedWork W1982726598 @default.
• W2155358348 hasRelatedWork W1982941324 @default.
• W2155358348 hasRelatedWork W2027766635 @default.
• W2155358348 hasRelatedWork W2048704715 @default.
• W2155358348 hasRelatedWork W2049967398 @default.
• W2155358348 hasRelatedWork W2151672582 @default.
• W2155358348 hasRelatedWork W2163021423 @default.
• W2155358348 hasRelatedWork W2235400136 @default.
• W2155358348 hasRelatedWork W762394346 @default.
• W2155358348 hasVolume "33" @default.
• W2155358348 isParatext "false" @default.
• W2155358348 isRetracted "false" @default.

• next