Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155363910> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2155363910 abstract "Objective: CD133 is a pentaspan membrane protein expressed by the so-called cancer stem cells (CSC) in the majority of human cancers. The aim of this study was to analyze CD133 expression levels in specimens of oral cancer and to evaluate its relation with disease evolution. Methods: Expression of the CD133 protein was evaluated by immunostaining in a series of oral squamous cell carcinoma (OSCC) and its relation with traditional prognostic indicators and the clinical outcome of patients was analyzed. Results: CD133 expression was highly variable amongst different samples with a median percentage of positive cells of 5 (range 0 - 80; mean = 11) and CD133 staining was not detectable in tumor cells in 29 (43%) cases. No correlation was observed with age at diagnosis, gender and grading while a significant correlation was observed with tumor stage. Kaplan-Meier curves of disease-free survival displayed a significant separation between the negative and positive groups of patients (p = 0.001 by log-rank test) but CD133 staining did not confirm to be an independent predictor of clinical outcome in a multivariate analyses. Conclusion: Expression of CD133 was detectable in the majority of OSCC samples and correlated significantly with tumor stage and the clinical outcome of patients in terms of disease-free survival. Further studies are warranted on a larger series of cases to elucidate the role of CD133 in the development and progression of OSCC and its suitability as a prognostic biomarker." @default.
- W2155363910 created "2016-06-24" @default.
- W2155363910 creator A5045787527 @default.
- W2155363910 date "2014-01-01" @default.
- W2155363910 modified "2023-09-30" @default.
- W2155363910 title "Expression of CD133 Correlates with Tumor Stage, Lymph Node Metastasis and Recurrence in Oral Squamous Cell Carcinoma" @default.
- W2155363910 cites W133253872 @default.
- W2155363910 cites W1985335182 @default.
- W2155363910 cites W1988803298 @default.
- W2155363910 cites W2009058560 @default.
- W2155363910 cites W2024065857 @default.
- W2155363910 cites W2028801216 @default.
- W2155363910 cites W2031446155 @default.
- W2155363910 cites W2058621808 @default.
- W2155363910 cites W2071946741 @default.
- W2155363910 cites W2076287811 @default.
- W2155363910 cites W2082175743 @default.
- W2155363910 cites W2087286423 @default.
- W2155363910 cites W2089233117 @default.
- W2155363910 cites W2099188406 @default.
- W2155363910 cites W2111059180 @default.
- W2155363910 cites W2117273788 @default.
- W2155363910 cites W2118124711 @default.
- W2155363910 cites W2122245635 @default.
- W2155363910 cites W2154635187 @default.
- W2155363910 cites W2161817637 @default.
- W2155363910 cites W2161983416 @default.
- W2155363910 cites W2166424982 @default.
- W2155363910 doi "https://doi.org/10.4172/1948-5956.1000255" @default.
- W2155363910 hasPublicationYear "2014" @default.
- W2155363910 type Work @default.
- W2155363910 sameAs 2155363910 @default.
- W2155363910 citedByCount "2" @default.
- W2155363910 countsByYear W21553639102014 @default.
- W2155363910 countsByYear W21553639102019 @default.
- W2155363910 crossrefType "journal-article" @default.
- W2155363910 hasAuthorship W2155363910A5045787527 @default.
- W2155363910 hasBestOaLocation W21553639101 @default.
- W2155363910 hasConcept C121608353 @default.
- W2155363910 hasConcept C126322002 @default.
- W2155363910 hasConcept C142724271 @default.
- W2155363910 hasConcept C143998085 @default.
- W2155363910 hasConcept C146357865 @default.
- W2155363910 hasConcept C1491633281 @default.
- W2155363910 hasConcept C151730666 @default.
- W2155363910 hasConcept C157585117 @default.
- W2155363910 hasConcept C2779013556 @default.
- W2155363910 hasConcept C2779720271 @default.
- W2155363910 hasConcept C2780849966 @default.
- W2155363910 hasConcept C2992571226 @default.
- W2155363910 hasConcept C3019992690 @default.
- W2155363910 hasConcept C502942594 @default.
- W2155363910 hasConcept C54355233 @default.
- W2155363910 hasConcept C60644358 @default.
- W2155363910 hasConcept C71924100 @default.
- W2155363910 hasConcept C86803240 @default.
- W2155363910 hasConceptScore W2155363910C121608353 @default.
- W2155363910 hasConceptScore W2155363910C126322002 @default.
- W2155363910 hasConceptScore W2155363910C142724271 @default.
- W2155363910 hasConceptScore W2155363910C143998085 @default.
- W2155363910 hasConceptScore W2155363910C146357865 @default.
- W2155363910 hasConceptScore W2155363910C1491633281 @default.
- W2155363910 hasConceptScore W2155363910C151730666 @default.
- W2155363910 hasConceptScore W2155363910C157585117 @default.
- W2155363910 hasConceptScore W2155363910C2779013556 @default.
- W2155363910 hasConceptScore W2155363910C2779720271 @default.
- W2155363910 hasConceptScore W2155363910C2780849966 @default.
- W2155363910 hasConceptScore W2155363910C2992571226 @default.
- W2155363910 hasConceptScore W2155363910C3019992690 @default.
- W2155363910 hasConceptScore W2155363910C502942594 @default.
- W2155363910 hasConceptScore W2155363910C54355233 @default.
- W2155363910 hasConceptScore W2155363910C60644358 @default.
- W2155363910 hasConceptScore W2155363910C71924100 @default.
- W2155363910 hasConceptScore W2155363910C86803240 @default.
- W2155363910 hasIssue "03" @default.
- W2155363910 hasLocation W21553639101 @default.
- W2155363910 hasLocation W21553639102 @default.
- W2155363910 hasOpenAccess W2155363910 @default.
- W2155363910 hasPrimaryLocation W21553639101 @default.
- W2155363910 hasRelatedWork W2041343500 @default.
- W2155363910 hasRelatedWork W2155363910 @default.
- W2155363910 hasRelatedWork W2341839242 @default.
- W2155363910 hasRelatedWork W2368014247 @default.
- W2155363910 hasRelatedWork W2381524002 @default.
- W2155363910 hasRelatedWork W2385555853 @default.
- W2155363910 hasRelatedWork W2395525374 @default.
- W2155363910 hasRelatedWork W2397497377 @default.
- W2155363910 hasRelatedWork W2884060043 @default.
- W2155363910 hasRelatedWork W5509621 @default.
- W2155363910 hasVolume "06" @default.
- W2155363910 isParatext "false" @default.
- W2155363910 isRetracted "false" @default.
- W2155363910 magId "2155363910" @default.
- W2155363910 workType "article" @default.