FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155366287> ?p ?o ?g. }

• W2155366287 endingPage "e1004775" @default.
• W2155366287 startingPage "e1004775" @default.
• W2155366287 abstract "In many species, genomic data have revealed pervasive adaptive evolution indicated by the fixation of beneficial alleles. However, when selection pressures are highly variable along a species range or through time adaptive alleles may persist at intermediate frequencies for long periods. So called balanced polymorphisms have long been understood to be an important component of standing genetic variation yet direct evidence of the strength of balancing selection and the stability and prevalence of balanced polymorphisms has remained elusive. We hypothesized that environmental fluctuations between seasons in a North American orchard would impose temporally variable selection on Drosophila melanogaster and consequently maintain allelic variation at polymorphisms adaptively evolving in response to climatic variation. We identified hundreds of polymorphisms whose frequency oscillates among seasons and argue that these loci are subject to strong, temporally variable selection. We show that these polymorphisms respond to acute and persistent changes in climate and are associated in predictable ways with seasonally variable phenotypes. In addition, we show that adaptively oscillating polymorphisms are likely millions of years old, with some likely predating the divergence between D. melanogaster and D. simulans. Taken together, our results demonstrate that rapid temporal fluctuations in climate over generational time promotes adaptive genetic diversity at loci affecting polygenic phenotypes." @default.
• W2155366287 created "2016-06-24" @default.
• W2155366287 creator A5004735385 @default.
• W2155366287 creator A5012626136 @default.
• W2155366287 creator A5064588905 @default.
• W2155366287 creator A5073659297 @default.
• W2155366287 creator A5090479369 @default.
• W2155366287 date "2014-11-06" @default.
• W2155366287 modified "2023-10-14" @default.
• W2155366287 title "Genomic Evidence of Rapid and Stable Adaptive Oscillations over Seasonal Time Scales in Drosophila" @default.
• W2155366287 cites W104362132 @default.
• W2155366287 cites W109821702 @default.
• W2155366287 cites W1562434007 @default.
• W2155366287 cites W1879457627 @default.
• W2155366287 cites W1918764356 @default.
• W2155366287 cites W1939346899 @default.
• W2155366287 cites W1941486497 @default.
• W2155366287 cites W1964558095 @default.
• W2155366287 cites W1964698454 @default.
• W2155366287 cites W1966247448 @default.
• W2155366287 cites W1966778471 @default.
• W2155366287 cites W1967585098 @default.
• W2155366287 cites W1968858700 @default.
• W2155366287 cites W1969541700 @default.
• W2155366287 cites W1970892318 @default.
• W2155366287 cites W1972091381 @default.
• W2155366287 cites W1973876530 @default.
• W2155366287 cites W1975942603 @default.
• W2155366287 cites W1978611977 @default.
• W2155366287 cites W1982284128 @default.
• W2155366287 cites W1983110723 @default.
• W2155366287 cites W1987636433 @default.
• W2155366287 cites W1990338025 @default.
• W2155366287 cites W1996546315 @default.
• W2155366287 cites W2000412446 @default.
• W2155366287 cites W2001108284 @default.
• W2155366287 cites W2003106166 @default.
• W2155366287 cites W2005609877 @default.
• W2155366287 cites W2006382841 @default.
• W2155366287 cites W2012296090 @default.
• W2155366287 cites W2013143779 @default.
• W2155366287 cites W2014335315 @default.
• W2155366287 cites W2017641297 @default.
• W2155366287 cites W2022851429 @default.
• W2155366287 cites W2023296362 @default.
• W2155366287 cites W2040212831 @default.
• W2155366287 cites W2041530975 @default.
• W2155366287 cites W2044397127 @default.
• W2155366287 cites W2044961839 @default.
• W2155366287 cites W2048923080 @default.
• W2155366287 cites W2058915771 @default.
• W2155366287 cites W2058992630 @default.
• W2155366287 cites W2061192754 @default.
• W2155366287 cites W2063733088 @default.
• W2155366287 cites W2065315896 @default.
• W2155366287 cites W2068831326 @default.
• W2155366287 cites W2069699877 @default.
• W2155366287 cites W2070845087 @default.
• W2155366287 cites W2072930970 @default.
• W2155366287 cites W2072959753 @default.
• W2155366287 cites W2073300538 @default.
• W2155366287 cites W2076383771 @default.
• W2155366287 cites W2081869206 @default.
• W2155366287 cites W2083634561 @default.
• W2155366287 cites W2086391970 @default.
• W2155366287 cites W2088009547 @default.
• W2155366287 cites W2088348113 @default.
• W2155366287 cites W2089203051 @default.
• W2155366287 cites W2091428973 @default.
• W2155366287 cites W2091560977 @default.
• W2155366287 cites W2097494519 @default.
• W2155366287 cites W2097870784 @default.
• W2155366287 cites W2099165877 @default.
• W2155366287 cites W2103441770 @default.
• W2155366287 cites W2104511903 @default.
• W2155366287 cites W2105987493 @default.
• W2155366287 cites W2106578986 @default.
• W2155366287 cites W2108234281 @default.
• W2155366287 cites W2110823979 @default.
• W2155366287 cites W2112397251 @default.
• W2155366287 cites W2113244577 @default.
• W2155366287 cites W2113283164 @default.
• W2155366287 cites W2114937342 @default.
• W2155366287 cites W2115392788 @default.
• W2155366287 cites W2117925179 @default.
• W2155366287 cites W2118734531 @default.
• W2155366287 cites W2119180969 @default.
• W2155366287 cites W2121419172 @default.
• W2155366287 cites W2123392556 @default.
• W2155366287 cites W2125063602 @default.
• W2155366287 cites W2126334905 @default.
• W2155366287 cites W2128016314 @default.
• W2155366287 cites W2128262534 @default.
• W2155366287 cites W2129436708 @default.
• W2155366287 cites W2130533928 @default.
• W2155366287 cites W2132437546 @default.
• W2155366287 cites W2135151038 @default.
• W2155366287 cites W2138007075 @default.

• next