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• W2155375798 abstract "In the present study, we investigated the inhibition of the Lux quorum-sensing system by N-acyl cyclopentylamine (Cn-CPA). The Lux quorum-sensing system regulates luminescence gene expression in Vibrio fischeri. We have already reported on the synthesis of Cn-CPA and their abilities as inhibitors of the quorum-sensing systems in Pseudomonas aeruginosa and Serratia marcescens. In the case of Pseudomonas aeruginosa (Las and Rhl quorum-sensing system) and Serratia marcescens (Spn quorum-sensing system), specific Cn-CPA with a particular acyl chain length showed the strongest inhibitory effect. In the case of the Lux quorum-sensing system, it was found that several kinds of Cn-CPA with a range from C5 to C10 showed similar strong inhibitory effects. Moreover, the inhibitory effect of Cn-CPA on the Lux quorum-sensing system was stronger than that of halogenated furanone, a natural quorum-sensing inhibitor." @default.
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• W2155375798 date "2008-12-01" @default.
• W2155375798 modified "2023-10-11" @default.
• W2155375798 title "Inhibition of Lux quorum-sensing system by synthetic &lt;italic&gt;N&lt;/italic&gt;-acyl-L-homoserine lactone analogous" @default.
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• W2155375798 doi "https://doi.org/10.1111/j.1745-7270.2008.00490.x" @default.
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