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- W2155393027 endingPage "938" @default.
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- W2155393027 abstract "<h3>Background</h3> Stiff-person syndrome is a rare autoimmune disorder associated with antibodies against glutamic acid decarboxylase (GAD), the key enzyme in γ-aminobutyric acid synthesis. In most cases, a trigger cannot be identified. <h3>Objective</h3> To describe a 41-year-old man who developed stiff-person syndrome and antibodies to GAD following acute West Nile virus infection. <h3>Design</h3> A case report and a search in GenBank for common epitopes. <h3>Result</h3> The search revealed a stretch of 12 amino acids in the NS1 protein of West Nile virus with a high degree of homology to the GAD65 region (an isoform of GAD) containing the PEVKEK motif. <h3>Conclusion</h3> Cross-reactivity between antibodies directed against West Nile virus and GAD may have contributed to the development of stiff-person syndrome in this patient." @default.
- W2155393027 created "2016-06-24" @default.
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- W2155393027 date "2004-06-01" @default.
- W2155393027 modified "2023-10-16" @default.
- W2155393027 title "Stiff-Person Syndrome Following West Nile Fever" @default.
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- W2155393027 doi "https://doi.org/10.1001/archneur.61.6.938" @default.
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