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- W2155452022 abstract "Mach's spiro! Bequem synthetisierbare heterosubstituierte Spiro[3.3]heptane sind generell besser wasserlöslich als analoge Cyclohexanderivate, und sie verfügen tendenziell über eine höhere metabolische Stabilität. Die neuen Bausteine lassen sich leicht in die Gerüste wirkstoffähnlicher Substanzen einbauen, wobei aktive Verbindungen mit ähnlicher oder höherer metabolischer Stabilität entstehen können, wie für Fluorchinolone gezeigt wird. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2155452022 date "2010-04-01" @default.
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- W2155452022 title "Synthese von azaspirocyclischen Bausteinen und deren Evaluierung für die Wirkstoff-Forschung" @default.
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