Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155454129> ?p ?o ?g. }
- W2155454129 endingPage "483" @default.
- W2155454129 startingPage "474" @default.
- W2155454129 abstract "Intracisternal A-particle (IAP)-specific sequences were 5- to 10-fold enriched in polyadenylated RNA from BALB/cJ thymus as compared with RNAs from liver, spleen, and kidney. The major transcripts of 7.2 and 5.4 kilobases were the same size as those found in an IAP-rich neuroblastoma cell line. The absolute levels and proportions of these transcripts varied in thymuses from mice of different inbred strains. With antiserum prepared against p73, the main IAP structural protein, several size classes of IAP-related proteins were immunoprecipitated from extracts of thymus cells incubated with [35S]methionine; these included p73 itself and a group of polypeptides in the size range of 114 to 120 kilodaltons (p114-p120). The inbred strains showed marked characteristic differences in the electrophoretic patterns of their IAP-related proteins. Earlier studies showed that the 7.2-kilobase RNA from neuroblastoma IAPs coded for p73 in a cell-free translation system. Correlations between the RNA and protein patterns in thymuses of the different inbred strains indicated that 5.4-kilobase RNA gives rise to the p114-p120 polypeptides. Metabolically labeled p120 was found to include methionine-containing tryptic peptides of p73 plus additional peptides consistent with its larger size. In vivo labeling kinetics showed that the p114-p120 polypeptides were not major precursors of p73 in intact neuroblastoma cells. This study shows that IAP gene expression in mouse thymus is genetically determined and that a novel class of IAP-related polypeptides can be expressed independently of the major particle structural protein." @default.
- W2155454129 created "2016-06-24" @default.
- W2155454129 creator A5055333894 @default.
- W2155454129 creator A5084100147 @default.
- W2155454129 date "1985-03-01" @default.
- W2155454129 modified "2023-09-24" @default.
- W2155454129 title "Intracisternal A-particle gene expression in normal mouse thymus tissue: gene products and strain-related variability" @default.
- W2155454129 cites W1480969767 @default.
- W2155454129 cites W1500703233 @default.
- W2155454129 cites W1530957404 @default.
- W2155454129 cites W1531870717 @default.
- W2155454129 cites W1535040048 @default.
- W2155454129 cites W1584410603 @default.
- W2155454129 cites W1659218167 @default.
- W2155454129 cites W1775749144 @default.
- W2155454129 cites W1876773210 @default.
- W2155454129 cites W1877182448 @default.
- W2155454129 cites W1968945805 @default.
- W2155454129 cites W1973746453 @default.
- W2155454129 cites W1974881263 @default.
- W2155454129 cites W1979798485 @default.
- W2155454129 cites W1987302058 @default.
- W2155454129 cites W1990205754 @default.
- W2155454129 cites W1991925546 @default.
- W2155454129 cites W1995567988 @default.
- W2155454129 cites W2001717481 @default.
- W2155454129 cites W2003206650 @default.
- W2155454129 cites W2011026101 @default.
- W2155454129 cites W2020615180 @default.
- W2155454129 cites W2029410264 @default.
- W2155454129 cites W2029987769 @default.
- W2155454129 cites W2030522563 @default.
- W2155454129 cites W2032073370 @default.
- W2155454129 cites W2040797453 @default.
- W2155454129 cites W2041794693 @default.
- W2155454129 cites W2052400179 @default.
- W2155454129 cites W2053205827 @default.
- W2155454129 cites W2059225262 @default.
- W2155454129 cites W2064518632 @default.
- W2155454129 cites W2065451764 @default.
- W2155454129 cites W2086101682 @default.
- W2155454129 cites W2100837269 @default.
- W2155454129 cites W2123794500 @default.
- W2155454129 cites W2287401987 @default.
- W2155454129 cites W2300174601 @default.
- W2155454129 cites W2422496743 @default.
- W2155454129 cites W46536988 @default.
- W2155454129 doi "https://doi.org/10.1128/mcb.5.3.474-483.1985" @default.
- W2155454129 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/366739" @default.
- W2155454129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2859519" @default.
- W2155454129 hasPublicationYear "1985" @default.
- W2155454129 type Work @default.
- W2155454129 sameAs 2155454129 @default.
- W2155454129 citedByCount "29" @default.
- W2155454129 countsByYear W21554541292019 @default.
- W2155454129 crossrefType "journal-article" @default.
- W2155454129 hasAuthorship W2155454129A5055333894 @default.
- W2155454129 hasAuthorship W2155454129A5084100147 @default.
- W2155454129 hasConcept C104317684 @default.
- W2155454129 hasConcept C105580179 @default.
- W2155454129 hasConcept C142575336 @default.
- W2155454129 hasConcept C150194340 @default.
- W2155454129 hasConcept C153911025 @default.
- W2155454129 hasConcept C159654299 @default.
- W2155454129 hasConcept C203014093 @default.
- W2155454129 hasConcept C2780912031 @default.
- W2155454129 hasConcept C2780931953 @default.
- W2155454129 hasConcept C515207424 @default.
- W2155454129 hasConcept C54355233 @default.
- W2155454129 hasConcept C55493867 @default.
- W2155454129 hasConcept C65666806 @default.
- W2155454129 hasConcept C67705224 @default.
- W2155454129 hasConcept C86803240 @default.
- W2155454129 hasConcept C88478588 @default.
- W2155454129 hasConcept C91523082 @default.
- W2155454129 hasConceptScore W2155454129C104317684 @default.
- W2155454129 hasConceptScore W2155454129C105580179 @default.
- W2155454129 hasConceptScore W2155454129C142575336 @default.
- W2155454129 hasConceptScore W2155454129C150194340 @default.
- W2155454129 hasConceptScore W2155454129C153911025 @default.
- W2155454129 hasConceptScore W2155454129C159654299 @default.
- W2155454129 hasConceptScore W2155454129C203014093 @default.
- W2155454129 hasConceptScore W2155454129C2780912031 @default.
- W2155454129 hasConceptScore W2155454129C2780931953 @default.
- W2155454129 hasConceptScore W2155454129C515207424 @default.
- W2155454129 hasConceptScore W2155454129C54355233 @default.
- W2155454129 hasConceptScore W2155454129C55493867 @default.
- W2155454129 hasConceptScore W2155454129C65666806 @default.
- W2155454129 hasConceptScore W2155454129C67705224 @default.
- W2155454129 hasConceptScore W2155454129C86803240 @default.
- W2155454129 hasConceptScore W2155454129C88478588 @default.
- W2155454129 hasConceptScore W2155454129C91523082 @default.
- W2155454129 hasIssue "3" @default.
- W2155454129 hasLocation W21554541291 @default.
- W2155454129 hasOpenAccess W2155454129 @default.
- W2155454129 hasPrimaryLocation W21554541291 @default.
- W2155454129 hasRelatedWork W1976021004 @default.
- W2155454129 hasRelatedWork W1981662335 @default.