FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155457708> ?p ?o ?g. }

• W2155457708 endingPage "7711" @default.
• W2155457708 startingPage "7703" @default.
• W2155457708 abstract "Abstract Purpose: This study determined the effect of 10% dietary flaxseed (FS) and tamoxifen (TAM), alone and in combination, on the growth of estrogen-dependent human breast cancer (MCF-7) in athymic mice with or without 17β-estradiol (E2) supplementation. Experimental Design: Ovariectomized mice received injection with MCF-7 cells, were implanted with an E2 pellet (1.7 mg), and fed the basal diet (BD). When tumor reached ∼40 mm2, the E2 implant was removed, and mice were randomized to the following groups and maintained at either low (E2 pellet removed) or high E2 level (new E2 pellet implanted) for 6 weeks: (a) positive control with new E2 pellet, fed BD, (b) negative control with no E2 implant, fed BD, (c) TAM group with TAM pellet (5 mg) implant, fed BD, (d) FS group fed 10% FS, (e) FS+TAM group with TAM implant, fed 10% FS. Tumor growth was monitored weekly. Results: At low E2 level, FS regressed the pretreatment tumor size by 74%. TAM regressed tumor initially but later induced an increase so that the tumor size was finally similar to the pretreatment size. A tumor regression &gt;53% was induced by FS+TAM than by TAM alone. At high E2 level, FS, TAM, and FS+TAM inhibited the tumor growth by 22, 41, and 50%, respectively, compared with the positive control. Decreased tumor size was attributable to reduced tumor cell proliferation and increased apoptosis. Conclusions: FS inhibited the growth of human estrogen-dependent breast cancer and strengthened the tumor-inhibitory effect of TAM at both low and high E2 levels." @default.
• W2155457708 created "2016-06-24" @default.
• W2155457708 creator A5009508386 @default.
• W2155457708 creator A5021954508 @default.
• W2155457708 creator A5032456908 @default.
• W2155457708 creator A5038289547 @default.
• W2155457708 date "2004-11-15" @default.
• W2155457708 modified "2023-09-23" @default.
• W2155457708 title "Dietary Flaxseed Enhances the Inhibitory Effect of Tamoxifen on the Growth of Estrogen-Dependent Human Breast Cancer (MCF-7) in Nude Mice" @default.
• W2155457708 cites W1601438131 @default.
• W2155457708 cites W1831301545 @default.
• W2155457708 cites W1841879426 @default.
• W2155457708 cites W1969094690 @default.
• W2155457708 cites W1969121458 @default.
• W2155457708 cites W1979078001 @default.
• W2155457708 cites W1985085751 @default.
• W2155457708 cites W1996269734 @default.
• W2155457708 cites W2006091725 @default.
• W2155457708 cites W2008305174 @default.
• W2155457708 cites W2008736555 @default.
• W2155457708 cites W2011692435 @default.
• W2155457708 cites W2017328640 @default.
• W2155457708 cites W2021780953 @default.
• W2155457708 cites W2023882753 @default.
• W2155457708 cites W2040883058 @default.
• W2155457708 cites W2048371302 @default.
• W2155457708 cites W2058587444 @default.
• W2155457708 cites W2059831787 @default.
• W2155457708 cites W2062843200 @default.
• W2155457708 cites W2072698554 @default.
• W2155457708 cites W2074493587 @default.
• W2155457708 cites W2077606638 @default.
• W2155457708 cites W2079783105 @default.
• W2155457708 cites W2084701385 @default.
• W2155457708 cites W2085374835 @default.
• W2155457708 cites W2100634348 @default.
• W2155457708 cites W2101701479 @default.
• W2155457708 cites W2105186145 @default.
• W2155457708 cites W2137656372 @default.
• W2155457708 cites W2157206717 @default.
• W2155457708 cites W2160261947 @default.
• W2155457708 cites W216451564 @default.
• W2155457708 cites W2216879932 @default.
• W2155457708 cites W2235080200 @default.
• W2155457708 cites W4233037919 @default.
• W2155457708 cites W4255602478 @default.
• W2155457708 cites W91452638 @default.
• W2155457708 doi "https://doi.org/10.1158/1078-0432.ccr-04-1130" @default.
• W2155457708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15570004" @default.
• W2155457708 hasPublicationYear "2004" @default.
• W2155457708 type Work @default.
• W2155457708 sameAs 2155457708 @default.
• W2155457708 citedByCount "90" @default.
• W2155457708 countsByYear W21554577082012 @default.
• W2155457708 countsByYear W21554577082013 @default.
• W2155457708 countsByYear W21554577082014 @default.
• W2155457708 countsByYear W21554577082015 @default.
• W2155457708 countsByYear W21554577082016 @default.
• W2155457708 countsByYear W21554577082017 @default.
• W2155457708 countsByYear W21554577082018 @default.
• W2155457708 countsByYear W21554577082019 @default.
• W2155457708 countsByYear W21554577082020 @default.
• W2155457708 countsByYear W21554577082021 @default.
• W2155457708 crossrefType "journal-article" @default.
• W2155457708 hasAuthorship W2155457708A5009508386 @default.
• W2155457708 hasAuthorship W2155457708A5021954508 @default.
• W2155457708 hasAuthorship W2155457708A5032456908 @default.
• W2155457708 hasAuthorship W2155457708A5038289547 @default.
• W2155457708 hasBestOaLocation W21554577081 @default.
• W2155457708 hasConcept C109541995 @default.
• W2155457708 hasConcept C121608353 @default.
• W2155457708 hasConcept C126322002 @default.
• W2155457708 hasConcept C134018914 @default.
• W2155457708 hasConcept C141071460 @default.
• W2155457708 hasConcept C2776067312 @default.
• W2155457708 hasConcept C2777164284 @default.
• W2155457708 hasConcept C2777176818 @default.
• W2155457708 hasConcept C2781411149 @default.
• W2155457708 hasConcept C2994423619 @default.
• W2155457708 hasConcept C530470458 @default.
• W2155457708 hasConcept C71924100 @default.
• W2155457708 hasConcept C8264082 @default.
• W2155457708 hasConcept C84606932 @default.
• W2155457708 hasConceptScore W2155457708C109541995 @default.
• W2155457708 hasConceptScore W2155457708C121608353 @default.
• W2155457708 hasConceptScore W2155457708C126322002 @default.
• W2155457708 hasConceptScore W2155457708C134018914 @default.
• W2155457708 hasConceptScore W2155457708C141071460 @default.
• W2155457708 hasConceptScore W2155457708C2776067312 @default.
• W2155457708 hasConceptScore W2155457708C2777164284 @default.
• W2155457708 hasConceptScore W2155457708C2777176818 @default.
• W2155457708 hasConceptScore W2155457708C2781411149 @default.
• W2155457708 hasConceptScore W2155457708C2994423619 @default.
• W2155457708 hasConceptScore W2155457708C530470458 @default.
• W2155457708 hasConceptScore W2155457708C71924100 @default.
• W2155457708 hasConceptScore W2155457708C8264082 @default.
• W2155457708 hasConceptScore W2155457708C84606932 @default.
• W2155457708 hasIssue "22" @default.

• next