Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155469691> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2155469691 endingPage "394" @default.
- W2155469691 startingPage "389" @default.
- W2155469691 abstract "The effect of infliximab on gluconeogenesis in an animal model of diet-induced liver glucose overproduction was investigated. The mice were treated with standard diet (SD group) or high fat diet (HFD group). HFD group were randomly divided and treated either with saline (100 µl/dose, ip, twice a day) or infliximab (10 µg in 100 µl saline per dose, ip, twice a day, i.e., 0.5 mg/kg per day). SD group also received saline. The treatment with infliximab or saline started on the first day of the introduction of the HFD and was maintained during two weeks. After this period, the mice were fasted (15 h) and anesthetized. After laparotomy, blood was collected for glucose determination followed by liver perfusion in which L-alanine (5 mM) was used as gluconeogenic substrate. HFD group treated with saline showed higher (p < 0.05) liver glucose production from L-alanine and fasting hyperglycemia. However, these metabolic changes were prevented by infliximab treatment. Therefore, this study suggested that infliximab could prevent the glucose overproduction and hyperglycemia related with glucose intolerance and type 2 diabetes." @default.
- W2155469691 created "2016-06-24" @default.
- W2155469691 creator A5020726830 @default.
- W2155469691 creator A5024617181 @default.
- W2155469691 creator A5045674056 @default.
- W2155469691 creator A5059998785 @default.
- W2155469691 creator A5063115128 @default.
- W2155469691 creator A5069134844 @default.
- W2155469691 date "2012-06-01" @default.
- W2155469691 modified "2023-10-14" @default.
- W2155469691 title "Infliximab treatment prevents hyperglycemia and the intensification of hepatic gluconeogenesis in an animal model of high fat diet-induced liver glucose overproduction" @default.
- W2155469691 cites W1995501935 @default.
- W2155469691 cites W2004424892 @default.
- W2155469691 cites W2016000655 @default.
- W2155469691 cites W2023478429 @default.
- W2155469691 cites W2044629416 @default.
- W2155469691 cites W2045164631 @default.
- W2155469691 cites W2049215243 @default.
- W2155469691 cites W2053832048 @default.
- W2155469691 cites W2066191605 @default.
- W2155469691 cites W2103309265 @default.
- W2155469691 cites W2109109507 @default.
- W2155469691 cites W2148689747 @default.
- W2155469691 cites W2149901579 @default.
- W2155469691 cites W2216666613 @default.
- W2155469691 cites W2596624061 @default.
- W2155469691 doi "https://doi.org/10.1590/s1516-89132012000300009" @default.
- W2155469691 hasPublicationYear "2012" @default.
- W2155469691 type Work @default.
- W2155469691 sameAs 2155469691 @default.
- W2155469691 citedByCount "3" @default.
- W2155469691 countsByYear W21554696912013 @default.
- W2155469691 countsByYear W21554696912014 @default.
- W2155469691 countsByYear W21554696912019 @default.
- W2155469691 crossrefType "journal-article" @default.
- W2155469691 hasAuthorship W2155469691A5020726830 @default.
- W2155469691 hasAuthorship W2155469691A5024617181 @default.
- W2155469691 hasAuthorship W2155469691A5045674056 @default.
- W2155469691 hasAuthorship W2155469691A5059998785 @default.
- W2155469691 hasAuthorship W2155469691A5063115128 @default.
- W2155469691 hasAuthorship W2155469691A5069134844 @default.
- W2155469691 hasBestOaLocation W21554696911 @default.
- W2155469691 hasConcept C126322002 @default.
- W2155469691 hasConcept C134018914 @default.
- W2155469691 hasConcept C17991360 @default.
- W2155469691 hasConcept C20904676 @default.
- W2155469691 hasConcept C2777138892 @default.
- W2155469691 hasConcept C2777397205 @default.
- W2155469691 hasConcept C555293320 @default.
- W2155469691 hasConcept C62231903 @default.
- W2155469691 hasConcept C71924100 @default.
- W2155469691 hasConceptScore W2155469691C126322002 @default.
- W2155469691 hasConceptScore W2155469691C134018914 @default.
- W2155469691 hasConceptScore W2155469691C17991360 @default.
- W2155469691 hasConceptScore W2155469691C20904676 @default.
- W2155469691 hasConceptScore W2155469691C2777138892 @default.
- W2155469691 hasConceptScore W2155469691C2777397205 @default.
- W2155469691 hasConceptScore W2155469691C555293320 @default.
- W2155469691 hasConceptScore W2155469691C62231903 @default.
- W2155469691 hasConceptScore W2155469691C71924100 @default.
- W2155469691 hasIssue "3" @default.
- W2155469691 hasLocation W21554696911 @default.
- W2155469691 hasLocation W21554696912 @default.
- W2155469691 hasLocation W21554696913 @default.
- W2155469691 hasOpenAccess W2155469691 @default.
- W2155469691 hasPrimaryLocation W21554696911 @default.
- W2155469691 hasRelatedWork W2000010456 @default.
- W2155469691 hasRelatedWork W2019806229 @default.
- W2155469691 hasRelatedWork W2025645904 @default.
- W2155469691 hasRelatedWork W2052448937 @default.
- W2155469691 hasRelatedWork W2064940611 @default.
- W2155469691 hasRelatedWork W2091844621 @default.
- W2155469691 hasRelatedWork W2156093747 @default.
- W2155469691 hasRelatedWork W2464596983 @default.
- W2155469691 hasRelatedWork W2963017100 @default.
- W2155469691 hasRelatedWork W4246710695 @default.
- W2155469691 hasVolume "55" @default.
- W2155469691 isParatext "false" @default.
- W2155469691 isRetracted "false" @default.
- W2155469691 magId "2155469691" @default.
- W2155469691 workType "article" @default.