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• W2155484322 endingPage "927" @default.
• W2155484322 startingPage "921" @default.
• W2155484322 abstract "This double-blind, placebo-controlled study investigated whether the application of an acaricide (Acarosan®) on mattresses and on textile floor coverings in living rooms and bedrooms can contribute to improvement in lung function and airway hyperresponsiveness in 40 adult asthmatic patients sensitized to house-dust mite. In a second group of 19 patients who refused chemical intervention, the clinical effects of application of allergen-impermeable mattress encasings were studied. In all three treatment groups, Der p 1 levels in mattress dust were statistically significantly decreased after 12 months. However, this decrease was much greater in the group who received mattress encasings (final mean level 430 ng/g) than in groups with acaricide- or placebo-treated mattresses (final mean levels 1730 and 2100 ng/g, respectively). Treatment of textile floors with either Acarosan or placebo chemical caused a statistically significant decrease in the level of the house-dust-mite allergen Der p 1 in floor dust. In the group with mattress encasings, no significant changes of floor dust Der p 1 were found. Airway hyperresponsiveness (as measured by the PC20 histamine) improved significantly in the mattress cover group after 6 months. The Acarosan group also showed a small but statistically significant improvement after 12 months." @default.
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• W2155484322 date "1997-09-01" @default.
• W2155484322 modified "2023-10-14" @default.
• W2155484322 title "Allergen-avoidance measures in homes of house-dust-mite-allergic asthmatic patients: effects of acaricides and mattress encasings" @default.
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• W2155484322 doi "https://doi.org/10.1111/j.1398-9995.1997.tb01252.x" @default.
• W2155484322 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9298177" @default.
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