Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155497243> ?p ?o ?g. }
- W2155497243 endingPage "37" @default.
- W2155497243 startingPage "37" @default.
- W2155497243 abstract "INTRODUCTION Alcohol withdrawal syndrome is an important problem for management of alcoholism. It is known that alcohol alters the function of neurotransmitters such as serotonin, but our review found no studies associating serotonin concentration changes with patient clinical status during detoxification. The authors hypothesized that total platelet serotonin concentration should significantly increase during alcohol detoxification. OBJECTIVE Assess possible association between total (endogenous and captured) platelet serotonin concentration and clinical status of patients with alcohol withdrawal syndrome, at beginning and end of detoxification with clomethiazole. METHODS Thirty-one alcohol-dependent patients, diagnosed with alcohol withdrawal syndrome according to DSM-IV and classified in three clinical groups (18-20, 21-22 and 23-26 points) per the Clinical Institute Withdrawal Assessment for Alcohol Scale, were included in a prospective case series from May 2009 through May 2011 at the Hermanos Ameijeiras Clinical-Surgical Teaching Hospital in Cuba. Patients were predominantly male (87%), ranging in age from 22 to 57 years; 40% were white, 40% mestizo and 20% black. All had been hospitalized for detoxification in the hospital's psychiatry service. Blood samples taken were mixed with 1% EDTA and centrifuged for isolating platelets. Serotonin concentrations (endogenous and captured) were measured within 2 hours of blood collection and mean values at treatment days 1 and 12 compared by t test (p 8 points at day 12. CONCLUSIONS Serotonin is a potential biomarker for initial clinical classification and outcome monitoring and could be useful to psychiatrists working with patients in this area of medical practice and research. Further studies including more patients and variables are necessary to support these preliminary results." @default.
- W2155497243 created "2016-06-24" @default.
- W2155497243 creator A5017751030 @default.
- W2155497243 creator A5071238614 @default.
- W2155497243 creator A5081101168 @default.
- W2155497243 creator A5083165958 @default.
- W2155497243 date "2014-01-01" @default.
- W2155497243 modified "2023-10-16" @default.
- W2155497243 title "Platelet Serotonin Concentration and Clinical Status in Alcohol Withdrawal Syndrome, Preliminary Results" @default.
- W2155497243 cites W129302348 @default.
- W2155497243 cites W13382641 @default.
- W2155497243 cites W148814078 @default.
- W2155497243 cites W1514933037 @default.
- W2155497243 cites W1775749144 @default.
- W2155497243 cites W182491304 @default.
- W2155497243 cites W1871203993 @default.
- W2155497243 cites W1965773300 @default.
- W2155497243 cites W1966750852 @default.
- W2155497243 cites W1980835881 @default.
- W2155497243 cites W1981211257 @default.
- W2155497243 cites W1991846003 @default.
- W2155497243 cites W2013488294 @default.
- W2155497243 cites W2041709780 @default.
- W2155497243 cites W2090521204 @default.
- W2155497243 cites W2091209219 @default.
- W2155497243 cites W2093918995 @default.
- W2155497243 cites W2114979176 @default.
- W2155497243 cites W2123282949 @default.
- W2155497243 cites W2124549431 @default.
- W2155497243 cites W2133037699 @default.
- W2155497243 cites W2135190897 @default.
- W2155497243 cites W2135222861 @default.
- W2155497243 cites W2137558691 @default.
- W2155497243 cites W2139746709 @default.
- W2155497243 cites W2141636993 @default.
- W2155497243 cites W2153715594 @default.
- W2155497243 cites W2159011576 @default.
- W2155497243 cites W2184115626 @default.
- W2155497243 cites W2469003612 @default.
- W2155497243 cites W2758682213 @default.
- W2155497243 doi "https://doi.org/10.37757/mr2014.v16.n1.8" @default.
- W2155497243 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24487674" @default.
- W2155497243 hasPublicationYear "2014" @default.
- W2155497243 type Work @default.
- W2155497243 sameAs 2155497243 @default.
- W2155497243 citedByCount "4" @default.
- W2155497243 countsByYear W21554972432015 @default.
- W2155497243 countsByYear W21554972432017 @default.
- W2155497243 countsByYear W21554972432020 @default.
- W2155497243 countsByYear W21554972432021 @default.
- W2155497243 crossrefType "journal-article" @default.
- W2155497243 hasAuthorship W2155497243A5017751030 @default.
- W2155497243 hasAuthorship W2155497243A5071238614 @default.
- W2155497243 hasAuthorship W2155497243A5081101168 @default.
- W2155497243 hasAuthorship W2155497243A5083165958 @default.
- W2155497243 hasBestOaLocation W21554972432 @default.
- W2155497243 hasConcept C118552586 @default.
- W2155497243 hasConcept C126322002 @default.
- W2155497243 hasConcept C170493617 @default.
- W2155497243 hasConcept C185592680 @default.
- W2155497243 hasConcept C2775864247 @default.
- W2155497243 hasConcept C2780179036 @default.
- W2155497243 hasConcept C2780873584 @default.
- W2155497243 hasConcept C2781066024 @default.
- W2155497243 hasConcept C2993802102 @default.
- W2155497243 hasConcept C3019635848 @default.
- W2155497243 hasConcept C37000724 @default.
- W2155497243 hasConcept C522683910 @default.
- W2155497243 hasConcept C55493867 @default.
- W2155497243 hasConcept C71924100 @default.
- W2155497243 hasConcept C89560881 @default.
- W2155497243 hasConceptScore W2155497243C118552586 @default.
- W2155497243 hasConceptScore W2155497243C126322002 @default.
- W2155497243 hasConceptScore W2155497243C170493617 @default.
- W2155497243 hasConceptScore W2155497243C185592680 @default.
- W2155497243 hasConceptScore W2155497243C2775864247 @default.
- W2155497243 hasConceptScore W2155497243C2780179036 @default.
- W2155497243 hasConceptScore W2155497243C2780873584 @default.
- W2155497243 hasConceptScore W2155497243C2781066024 @default.
- W2155497243 hasConceptScore W2155497243C2993802102 @default.
- W2155497243 hasConceptScore W2155497243C3019635848 @default.
- W2155497243 hasConceptScore W2155497243C37000724 @default.
- W2155497243 hasConceptScore W2155497243C522683910 @default.
- W2155497243 hasConceptScore W2155497243C55493867 @default.
- W2155497243 hasConceptScore W2155497243C71924100 @default.
- W2155497243 hasConceptScore W2155497243C89560881 @default.
- W2155497243 hasIssue "1" @default.
- W2155497243 hasLocation W21554972431 @default.
- W2155497243 hasLocation W21554972432 @default.
- W2155497243 hasOpenAccess W2155497243 @default.
- W2155497243 hasPrimaryLocation W21554972431 @default.
- W2155497243 hasRelatedWork W13546545 @default.
- W2155497243 hasRelatedWork W1980117556 @default.
- W2155497243 hasRelatedWork W1984608395 @default.
- W2155497243 hasRelatedWork W1989013875 @default.
- W2155497243 hasRelatedWork W2024761505 @default.
- W2155497243 hasRelatedWork W2053985236 @default.
- W2155497243 hasRelatedWork W2153743069 @default.