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• W2155529634 abstract "Objectives The aim was to report an unusual trizygotic pregnancy that resulted in live-born twins. The placenta of one twin had placental mesenchymal dysplasia (PMD), which resulted from a chimeric fusion of an androgenetic zygote and a normal biparental zygote. The literature review was summarized. Methods The case was first detected by prenatal ultrasound, and was then followed by a histologic and detailed genetic investigation. The literature on PMD, complete hydatidiform moles (CHMs), and placental mosaicism and chimerism was also reviewed. Results One placenta of a twin pregnancy was noted to be diffusely cystic and enlarged. The macroscopic and microscopic findings were consistent with the diagnosis of PMD; however, genetic findings confirmed confined placental chimerism involving a normal biparental 46,XY male conceptus and an androgenetic 46,XX complete hydatidiform mole. Conclusions This case represents a rare placental abnormality, PMD, which may have a diverse etiology. Therefore, detailed histologic and genetic analysis were performed for an accurate diagnosis. Copyright © 2005 John Wiley & Sons, Ltd." @default.
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• W2155529634 date "2005-01-01" @default.
• W2155529634 modified "2023-10-12" @default.
• W2155529634 title "Twin pregnancy with a chimeric androgenetic and biparental placenta in one twin displaying placental mesenchymal dysplasia phenotype" @default.
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• W2155529634 doi "https://doi.org/10.1002/pd.1255" @default.
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