FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155619341> ?p ?o ?g. }

• W2155619341 abstract "The laboratory rat (Rattus norvegicus) is an important model for studying many aspects of human health and disease. Detailed knowledge on genetic variation between strains is important from a biomedical, particularly pharmacogenetic point of view and useful for marker selection for genetic cloning and association studies.We show that Single Nucleotide Polymorphisms (SNPs) in commonly used rat strains are surprisingly well represented in wild rat isolates. Shotgun sequencing of 814 Kbp in one wild rat resulted in the identification of 485 SNPs as compared with the Brown Norway genome sequence. Genotyping 36 commonly used inbred rat strains showed that 84% of these alleles are also polymorphic in a representative set of laboratory rat strains.We postulate that shotgun sequencing in a wild rat sample and subsequent genotyping in multiple laboratory or domesticated strains rather than direct shotgun sequencing of multiple strains, could be the most efficient SNP discovery approach. For the rat, laboratory strains still harbor a large portion of the haplotypes present in wild isolates, suggesting a relatively recent common origin and supporting the idea that rat inbred strains, in contrast to mouse inbred strains, originate from a single species, R. norvegicus." @default.
• W2155619341 created "2016-06-24" @default.
• W2155619341 creator A5000250941 @default.
• W2155619341 creator A5010241937 @default.
• W2155619341 creator A5015272676 @default.
• W2155619341 creator A5050979301 @default.
• W2155619341 creator A5056884202 @default.
• W2155619341 creator A5072084304 @default.
• W2155619341 date "2005-11-29" @default.
• W2155619341 modified "2023-10-08" @default.
• W2155619341 title "Efficient single nucleotide polymorphism discovery in laboratory rat strains using wild rat-derived SNP candidates" @default.
• W2155619341 cites W1499500424 @default.
• W2155619341 cites W1589799005 @default.
• W2155619341 cites W1971307410 @default.
• W2155619341 cites W1995684371 @default.
• W2155619341 cites W2003872525 @default.
• W2155619341 cites W2007991295 @default.
• W2155619341 cites W2024057264 @default.
• W2155619341 cites W2050499823 @default.
• W2155619341 cites W2060889777 @default.
• W2155619341 cites W2072568060 @default.
• W2155619341 cites W2076193053 @default.
• W2155619341 cites W2083345304 @default.
• W2155619341 cites W2096420865 @default.
• W2155619341 cites W2097040991 @default.
• W2155619341 cites W2104397421 @default.
• W2155619341 cites W2107811029 @default.
• W2155619341 cites W2123828287 @default.
• W2155619341 cites W2127120893 @default.
• W2155619341 cites W2128481086 @default.
• W2155619341 cites W2129278924 @default.
• W2155619341 cites W2131884658 @default.
• W2155619341 cites W2136145671 @default.
• W2155619341 cites W2136491105 @default.
• W2155619341 cites W2148871416 @default.
• W2155619341 cites W2158818664 @default.
• W2155619341 cites W2164202215 @default.
• W2155619341 cites W2168380862 @default.
• W2155619341 cites W2171963306 @default.
• W2155619341 cites W2172196099 @default.
• W2155619341 cites W2288745116 @default.
• W2155619341 cites W2397741787 @default.
• W2155619341 cites W2418187546 @default.
• W2155619341 cites W2580933719 @default.
• W2155619341 doi "https://doi.org/10.1186/1471-2164-6-170" @default.
• W2155619341 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1318490" @default.
• W2155619341 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16316463" @default.
• W2155619341 hasPublicationYear "2005" @default.
• W2155619341 type Work @default.
• W2155619341 sameAs 2155619341 @default.
• W2155619341 citedByCount "18" @default.
• W2155619341 countsByYear W21556193412015 @default.
• W2155619341 countsByYear W21556193412016 @default.
• W2155619341 countsByYear W21556193412017 @default.
• W2155619341 countsByYear W21556193412018 @default.
• W2155619341 countsByYear W21556193412019 @default.
• W2155619341 countsByYear W21556193412021 @default.
• W2155619341 crossrefType "journal-article" @default.
• W2155619341 hasAuthorship W2155619341A5000250941 @default.
• W2155619341 hasAuthorship W2155619341A5010241937 @default.
• W2155619341 hasAuthorship W2155619341A5015272676 @default.
• W2155619341 hasAuthorship W2155619341A5050979301 @default.
• W2155619341 hasAuthorship W2155619341A5056884202 @default.
• W2155619341 hasAuthorship W2155619341A5072084304 @default.
• W2155619341 hasBestOaLocation W21556193411 @default.
• W2155619341 hasConcept C101985253 @default.
• W2155619341 hasConcept C104317684 @default.
• W2155619341 hasConcept C135763542 @default.
• W2155619341 hasConcept C139275648 @default.
• W2155619341 hasConcept C141231307 @default.
• W2155619341 hasConcept C153209595 @default.
• W2155619341 hasConcept C163691529 @default.
• W2155619341 hasConcept C180754005 @default.
• W2155619341 hasConcept C197754878 @default.
• W2155619341 hasConcept C31467283 @default.
• W2155619341 hasConcept C54355233 @default.
• W2155619341 hasConcept C76725341 @default.
• W2155619341 hasConcept C86803240 @default.
• W2155619341 hasConceptScore W2155619341C101985253 @default.
• W2155619341 hasConceptScore W2155619341C104317684 @default.
• W2155619341 hasConceptScore W2155619341C135763542 @default.
• W2155619341 hasConceptScore W2155619341C139275648 @default.
• W2155619341 hasConceptScore W2155619341C141231307 @default.
• W2155619341 hasConceptScore W2155619341C153209595 @default.
• W2155619341 hasConceptScore W2155619341C163691529 @default.
• W2155619341 hasConceptScore W2155619341C180754005 @default.
• W2155619341 hasConceptScore W2155619341C197754878 @default.
• W2155619341 hasConceptScore W2155619341C31467283 @default.
• W2155619341 hasConceptScore W2155619341C54355233 @default.
• W2155619341 hasConceptScore W2155619341C76725341 @default.
• W2155619341 hasConceptScore W2155619341C86803240 @default.
• W2155619341 hasIssue "1" @default.
• W2155619341 hasLocation W21556193411 @default.
• W2155619341 hasLocation W21556193412 @default.
• W2155619341 hasLocation W21556193413 @default.
• W2155619341 hasLocation W21556193414 @default.
• W2155619341 hasOpenAccess W2155619341 @default.
• W2155619341 hasPrimaryLocation W21556193411 @default.
• W2155619341 hasRelatedWork W1509356867 @default.
• W2155619341 hasRelatedWork W1663907732 @default.

• next