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- W2155631934 abstract "In November 2002, an advisory board meeting was convened by Novartis Pharma to provide recommendations and rationale for clinical trials designed to evaluate new treatments, such as TCH346, for amyotrophic lateral sclerosis (ALS). In terms of selecting appropriate outcome measures, the panel recommended the use of the ALS Functional Rating Scale (ALSFRS‐R) to measure primary endpoints. A review of other key issues in this area including regional variations in the epidemiology, diagnosis and management of ALS, defining patient populations and doses of trial medication, and accommodating the likelihood of co‐medication with pre‐existing treatment in trial design, are discussed." @default.
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- W2155631934 date "2004-01-01" @default.
- W2155631934 modified "2023-10-02" @default.
- W2155631934 title "Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial" @default.
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- W2155631934 doi "https://doi.org/10.1080/14660820410020187" @default.
- W2155631934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15204010" @default.
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