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- W2155652172 abstract "Objective: Metabolic activity and blood flow are key factors that generate and heat in the body. Heat can be quantitatively detected as emitted infrared (IR) energy. Here we investigate the feasibility of using IR imaging as a monitor of metabolic and perfusion changes in rat cecum caused by brief ischemia and reperfusion. Methods: Four male Sprague -Dawley rats weighing 200 to 300 g were anesthetized with Pentobarbital 5 mg/Kg. A rectal probe was used to measure core temperature. The cecum was exposed via midline laparotomy and mounted on a glass plate. Blood pressure was monitored via a femoral artery cannula. The aorta was cross-clamped for 1minute, and then released. Reperfusion was confirmed by return of femoral blood pressure waveform. Infrared images were taken prior to clamping, at 1minute of ischemia, and at 60 and 120 seconds of reperfusion. The infrared images were taken using the FLIR (Wilsonville, OR) camera model SC640. Image analysis was carried out using the ThermaCAM Quickview software. Data are expressed as Mean +/− Standard Error, statistical comparison using Student’s paired t test. Results: Upon aortic clamping, the cecal temperature fell severely, and continued to fall during the remainder of the experiment, despite reperfusion. The cecum to body temperature difference increased to 11.6 (+/−.7)C from a pre-clamp baseline of 8.6 (+/− 0.9)C, p< 0.05. Representative images are shown: Baseline 120 seconds reperfusion View Large Image Figure Viewer Conclusion: There is significant increase in temperature gradient in exposed bowel segments during mesenteric ischemia that does not immediately improve during reperfusion. Further experiments will be needed to clarify the pattern of thermal homeostasis in reperfused segments of bowel." @default.
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- W2155652172 date "2008-02-01" @default.
- W2155652172 modified "2023-09-27" @default.
- W2155652172 title "QS392. Reperfusion Does not Correct Acute Heat Deficit in Short Term Intestinal Ischemia" @default.
- W2155652172 doi "https://doi.org/10.1016/j.jss.2007.12.646" @default.
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