Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155677478> ?p ?o ?g. }
- W2155677478 endingPage "1827" @default.
- W2155677478 startingPage "1822" @default.
- W2155677478 abstract "The precise cellular mechanism of primordial germ cell (PGC) migration remains unknown. Cell surface galactosyltransferase (GalTase) is known to play unique roles in the process of locomotion of many migratory cells. With an objective to seek evidence for possible involvement of GalTase in the migratory process of PGC, we evaluated germ cell migration in the rat following experimental modulation of embryonic GalTase activity. Pregnant rats were laparotomized under anesthesia on Day 10 of pregnancy. While embryos of one uterine horn received lysozyme (100 microg/fetus), those of the other received alpha-lactalbumin (LA; 100 microg/fetus), N-acetylglucosamine (GlcNAc; 250 nmole/fetus), uridine 5'-monophosphate (UMP; 2.5 micromole/fetus), uridine diphosphate-galactose (UDP-gal; 250 nmole/fetus), or a combination of 250 nmole of UDP-gal and 2.5 micromole of UMP/fetus. Between gestation Days 12 and 14, embryos were dissected out and processed for histochemical localization of PGC on the basis of binding of Dolichos biflorus agglutinin on the surface glycoconjugate of the germ cells. The number of PGC in each embryo was counted. There was a daywise increase in the number of PGC in all groups. As compared with lysozyme-exposed controls, the numbers of PGCs at the day-specific sites on all days of examination were significantly lower in the LA- as well as GlcNAc-exposed groups. UMP or UDP-gal individually exerted little or no influence, while the total PGC count rose significantly over the respective control values under simultaneous exposure to UMP and UDP-gal. The present findings suggest a likely catalytic role of GalTase in the process of germ cell migration." @default.
- W2155677478 created "2016-06-24" @default.
- W2155677478 creator A5002425752 @default.
- W2155677478 creator A5016352624 @default.
- W2155677478 creator A5034872746 @default.
- W2155677478 creator A5038444366 @default.
- W2155677478 creator A5052339845 @default.
- W2155677478 creator A5082888439 @default.
- W2155677478 date "2004-12-01" @default.
- W2155677478 modified "2023-10-01" @default.
- W2155677478 title "Primordial Germ Cell Migration in the Rat: Preliminary Evidence for a Role of Galactosyltransferase1" @default.
- W2155677478 cites W1511974988 @default.
- W2155677478 cites W1762028152 @default.
- W2155677478 cites W1965538122 @default.
- W2155677478 cites W1971355686 @default.
- W2155677478 cites W1977409351 @default.
- W2155677478 cites W1982131709 @default.
- W2155677478 cites W1989850828 @default.
- W2155677478 cites W1991119501 @default.
- W2155677478 cites W1993662880 @default.
- W2155677478 cites W2000113718 @default.
- W2155677478 cites W2006387884 @default.
- W2155677478 cites W2013041942 @default.
- W2155677478 cites W2017104531 @default.
- W2155677478 cites W2017552179 @default.
- W2155677478 cites W2019516931 @default.
- W2155677478 cites W2022341048 @default.
- W2155677478 cites W2024008950 @default.
- W2155677478 cites W2031034856 @default.
- W2155677478 cites W2044791449 @default.
- W2155677478 cites W2046489297 @default.
- W2155677478 cites W2056755246 @default.
- W2155677478 cites W2066349272 @default.
- W2155677478 cites W2070824500 @default.
- W2155677478 cites W2076519306 @default.
- W2155677478 cites W2089500869 @default.
- W2155677478 cites W2104151754 @default.
- W2155677478 cites W2111166148 @default.
- W2155677478 cites W2157760203 @default.
- W2155677478 cites W2158649743 @default.
- W2155677478 cites W2159601173 @default.
- W2155677478 cites W2164049278 @default.
- W2155677478 doi "https://doi.org/10.1095/biolreprod.104.028555" @default.
- W2155677478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15286041" @default.
- W2155677478 hasPublicationYear "2004" @default.
- W2155677478 type Work @default.
- W2155677478 sameAs 2155677478 @default.
- W2155677478 citedByCount "5" @default.
- W2155677478 countsByYear W21556774782012 @default.
- W2155677478 countsByYear W21556774782013 @default.
- W2155677478 countsByYear W21556774782014 @default.
- W2155677478 crossrefType "journal-article" @default.
- W2155677478 hasAuthorship W2155677478A5002425752 @default.
- W2155677478 hasAuthorship W2155677478A5016352624 @default.
- W2155677478 hasAuthorship W2155677478A5034872746 @default.
- W2155677478 hasAuthorship W2155677478A5038444366 @default.
- W2155677478 hasAuthorship W2155677478A5052339845 @default.
- W2155677478 hasAuthorship W2155677478A5082888439 @default.
- W2155677478 hasBestOaLocation W21556774781 @default.
- W2155677478 hasConcept C104317684 @default.
- W2155677478 hasConcept C126322002 @default.
- W2155677478 hasConcept C134018914 @default.
- W2155677478 hasConcept C13426554 @default.
- W2155677478 hasConcept C16685009 @default.
- W2155677478 hasConcept C172680121 @default.
- W2155677478 hasConcept C181199279 @default.
- W2155677478 hasConcept C196843134 @default.
- W2155677478 hasConcept C19869320 @default.
- W2155677478 hasConcept C202751555 @default.
- W2155677478 hasConcept C203014093 @default.
- W2155677478 hasConcept C2779122487 @default.
- W2155677478 hasConcept C2779234561 @default.
- W2155677478 hasConcept C2780175098 @default.
- W2155677478 hasConcept C2780758401 @default.
- W2155677478 hasConcept C2780895608 @default.
- W2155677478 hasConcept C2781259782 @default.
- W2155677478 hasConcept C54355233 @default.
- W2155677478 hasConcept C55493867 @default.
- W2155677478 hasConcept C67705224 @default.
- W2155677478 hasConcept C71924100 @default.
- W2155677478 hasConcept C86803240 @default.
- W2155677478 hasConcept C95444343 @default.
- W2155677478 hasConceptScore W2155677478C104317684 @default.
- W2155677478 hasConceptScore W2155677478C126322002 @default.
- W2155677478 hasConceptScore W2155677478C134018914 @default.
- W2155677478 hasConceptScore W2155677478C13426554 @default.
- W2155677478 hasConceptScore W2155677478C16685009 @default.
- W2155677478 hasConceptScore W2155677478C172680121 @default.
- W2155677478 hasConceptScore W2155677478C181199279 @default.
- W2155677478 hasConceptScore W2155677478C196843134 @default.
- W2155677478 hasConceptScore W2155677478C19869320 @default.
- W2155677478 hasConceptScore W2155677478C202751555 @default.
- W2155677478 hasConceptScore W2155677478C203014093 @default.
- W2155677478 hasConceptScore W2155677478C2779122487 @default.
- W2155677478 hasConceptScore W2155677478C2779234561 @default.
- W2155677478 hasConceptScore W2155677478C2780175098 @default.
- W2155677478 hasConceptScore W2155677478C2780758401 @default.
- W2155677478 hasConceptScore W2155677478C2780895608 @default.