Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155683676> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2155683676 endingPage "473" @default.
- W2155683676 startingPage "467" @default.
- W2155683676 abstract "We studied the bronchodilator effects of inhaled fenoterol, a relatively selective beta-2 adrenergic agent, and ipratropium an anticholinergic drug, singly and in combination in 10 patients with asthma. The period of observation was 6 hr after aerosol administration. The six drug regimens used were fenoterol 100 micrograms, fenoterol 200 micrograms fenoterol 50 micrograms combined with 20 micrograms of ipratropium, fenoterol 100 micrograms combined with 40 micrograms of ipratropium, 40 micrograms of ipratropium, and placebo. Measurements consisted of spirometry with determination of forced expiratory volume in one second (FEV1), maximal expiratory flow at 50% of vital capacity (V50), specific airway conductance, lung volumes, and heart rate. Bronchodilation with regimens containing fenoterol was rapid, with 75% of the maximum response achieved by 5 min, while the peak effect of ipratropium was delayed for 1 to 2 hr. Fenoterol 100 micrograms produced approximately half the degree of improvement in FEV1 and V50 compared with 200 micrograms of fenoterol. The addition of 40 micrograms of ipratropium to 100 micrograms of fenoterol resulted in bronchodilation equivalent to 200 micrograms fenoterol and was associated with a more prolonged effect than fenoterol 100 micrograms. Tremor was observed in two-subjects inhaling fenoterol 200 micrograms but was not observed with any other regimen. It is concluded that the combination of inhaled ipratropium and fenoterol is an effective bronchodilator in asthma, achieving efficacy similar to that of fenoterol alone but with fewer side effects." @default.
- W2155683676 created "2016-06-24" @default.
- W2155683676 creator A5074986387 @default.
- W2155683676 creator A5090871463 @default.
- W2155683676 date "1982-05-01" @default.
- W2155683676 modified "2023-09-27" @default.
- W2155683676 title "The short-term bronchodilator effects of fenoterol and ipratropium in asthma" @default.
- W2155683676 cites W1746338220 @default.
- W2155683676 cites W1992897439 @default.
- W2155683676 cites W2020098541 @default.
- W2155683676 cites W2023155391 @default.
- W2155683676 cites W2024518767 @default.
- W2155683676 cites W2057309255 @default.
- W2155683676 cites W206035007 @default.
- W2155683676 cites W2099947428 @default.
- W2155683676 cites W2105738953 @default.
- W2155683676 cites W2107052422 @default.
- W2155683676 cites W2131940348 @default.
- W2155683676 cites W2147041353 @default.
- W2155683676 cites W2179651660 @default.
- W2155683676 cites W2212853496 @default.
- W2155683676 cites W2280607089 @default.
- W2155683676 cites W2351197400 @default.
- W2155683676 cites W2396784958 @default.
- W2155683676 cites W2405919573 @default.
- W2155683676 cites W2412989419 @default.
- W2155683676 cites W2747566783 @default.
- W2155683676 doi "https://doi.org/10.1016/0091-6749(82)90123-3" @default.
- W2155683676 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6210726" @default.
- W2155683676 hasPublicationYear "1982" @default.
- W2155683676 type Work @default.
- W2155683676 sameAs 2155683676 @default.
- W2155683676 citedByCount "36" @default.
- W2155683676 countsByYear W21556836762012 @default.
- W2155683676 countsByYear W21556836762020 @default.
- W2155683676 countsByYear W21556836762021 @default.
- W2155683676 crossrefType "journal-article" @default.
- W2155683676 hasAuthorship W2155683676A5074986387 @default.
- W2155683676 hasAuthorship W2155683676A5090871463 @default.
- W2155683676 hasBestOaLocation W21556836761 @default.
- W2155683676 hasConcept C126322002 @default.
- W2155683676 hasConcept C165637977 @default.
- W2155683676 hasConcept C2775906890 @default.
- W2155683676 hasConcept C2776042228 @default.
- W2155683676 hasConcept C2777714996 @default.
- W2155683676 hasConcept C2780532441 @default.
- W2155683676 hasConcept C2781018748 @default.
- W2155683676 hasConcept C2908646376 @default.
- W2155683676 hasConcept C2909577894 @default.
- W2155683676 hasConcept C3018587741 @default.
- W2155683676 hasConcept C42219234 @default.
- W2155683676 hasConcept C55520419 @default.
- W2155683676 hasConcept C71924100 @default.
- W2155683676 hasConcept C98274493 @default.
- W2155683676 hasConceptScore W2155683676C126322002 @default.
- W2155683676 hasConceptScore W2155683676C165637977 @default.
- W2155683676 hasConceptScore W2155683676C2775906890 @default.
- W2155683676 hasConceptScore W2155683676C2776042228 @default.
- W2155683676 hasConceptScore W2155683676C2777714996 @default.
- W2155683676 hasConceptScore W2155683676C2780532441 @default.
- W2155683676 hasConceptScore W2155683676C2781018748 @default.
- W2155683676 hasConceptScore W2155683676C2908646376 @default.
- W2155683676 hasConceptScore W2155683676C2909577894 @default.
- W2155683676 hasConceptScore W2155683676C3018587741 @default.
- W2155683676 hasConceptScore W2155683676C42219234 @default.
- W2155683676 hasConceptScore W2155683676C55520419 @default.
- W2155683676 hasConceptScore W2155683676C71924100 @default.
- W2155683676 hasConceptScore W2155683676C98274493 @default.
- W2155683676 hasIssue "5" @default.
- W2155683676 hasLocation W21556836761 @default.
- W2155683676 hasLocation W21556836762 @default.
- W2155683676 hasOpenAccess W2155683676 @default.
- W2155683676 hasPrimaryLocation W21556836761 @default.
- W2155683676 hasRelatedWork W1894320832 @default.
- W2155683676 hasRelatedWork W1966829095 @default.
- W2155683676 hasRelatedWork W1971722072 @default.
- W2155683676 hasRelatedWork W1985515803 @default.
- W2155683676 hasRelatedWork W2022073865 @default.
- W2155683676 hasRelatedWork W2031990050 @default.
- W2155683676 hasRelatedWork W2137718446 @default.
- W2155683676 hasRelatedWork W2396754048 @default.
- W2155683676 hasRelatedWork W2405701194 @default.
- W2155683676 hasRelatedWork W99239007 @default.
- W2155683676 hasVolume "69" @default.
- W2155683676 isParatext "false" @default.
- W2155683676 isRetracted "false" @default.
- W2155683676 magId "2155683676" @default.
- W2155683676 workType "article" @default.