Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155701384> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2155701384 endingPage "1204" @default.
- W2155701384 startingPage "1199" @default.
- W2155701384 abstract "The aim of this study was to investigate the role of phosphatidylinositol 3-kinase (PI3 kinase) and the mitogen- activating protein (MAP) kinase pathway on the differentiation of ovine preadipocytes. In order to investigate this issue, we monitored glycerol 3-phosphate dehydrogenase (GPDH) activity during differentiation with specific inhibitors of PI3 kinase and MAP kinase-Erk kinase, LY294002 and PD098059, respectively. The preadipocytes, which were obtained from ovine subcutaneous adipose tissues, were proliferated to confluence and then differentiated to adipocytes in differentiation medium with each inhibitor for 10 days. The confluent preadipocytes and differentiated adipocytes at days 3, 7 and 10 were harvested for assay of GPDH activity. LY294002 inhibited the differentiation program in dose- and day-dependent manners during 10 days of differentiation. PD098059 did not affect GPDH activity during differentiation. Furthermore, the expression of peroxisome proliferator-activated receptor γ2 (PPAR-γ2), the representative early gene of differentiation, was markedly reduced by LY294002 treatment, although PD098059 did not change it. Our results demonstrated that the activation of PI3 kinase contributes to the differentiation process of ovine preadipocytes. (Asian-Aust. J. Anim. Sci. 2003. Vol 16, No. 8 : 1199-1204)" @default.
- W2155701384 created "2016-06-24" @default.
- W2155701384 creator A5011441043 @default.
- W2155701384 creator A5012361101 @default.
- W2155701384 creator A5040672818 @default.
- W2155701384 creator A5042279691 @default.
- W2155701384 creator A5062232273 @default.
- W2155701384 creator A5065254374 @default.
- W2155701384 creator A5077354575 @default.
- W2155701384 creator A5084466098 @default.
- W2155701384 date "2003-01-01" @default.
- W2155701384 modified "2023-10-04" @default.
- W2155701384 title "The Role of Phosphatidylinositol 3-kinase and Mitogenic Activated Protein Kinase on the Differentiation of Ovine Preadipocytes" @default.
- W2155701384 cites W1551443142 @default.
- W2155701384 cites W1568605582 @default.
- W2155701384 cites W1797700808 @default.
- W2155701384 cites W1815087127 @default.
- W2155701384 cites W1843523988 @default.
- W2155701384 cites W1907219612 @default.
- W2155701384 cites W1981954545 @default.
- W2155701384 cites W1984706102 @default.
- W2155701384 cites W2020331673 @default.
- W2155701384 cites W2036678887 @default.
- W2155701384 cites W2037415341 @default.
- W2155701384 cites W2046078740 @default.
- W2155701384 cites W2054760273 @default.
- W2155701384 cites W2059198255 @default.
- W2155701384 cites W2059215353 @default.
- W2155701384 cites W2063921652 @default.
- W2155701384 cites W2075097891 @default.
- W2155701384 cites W2083151522 @default.
- W2155701384 cites W2089731973 @default.
- W2155701384 cites W2093706331 @default.
- W2155701384 cites W2111478729 @default.
- W2155701384 cites W2128635872 @default.
- W2155701384 cites W2134064618 @default.
- W2155701384 cites W2135778926 @default.
- W2155701384 cites W2136208727 @default.
- W2155701384 cites W2139440574 @default.
- W2155701384 cites W2148244700 @default.
- W2155701384 cites W2155437852 @default.
- W2155701384 cites W2160852563 @default.
- W2155701384 cites W2162481722 @default.
- W2155701384 cites W2164015929 @default.
- W2155701384 cites W38857139 @default.
- W2155701384 doi "https://doi.org/10.5713/ajas.2003.1199" @default.
- W2155701384 hasPublicationYear "2003" @default.
- W2155701384 type Work @default.
- W2155701384 sameAs 2155701384 @default.
- W2155701384 citedByCount "2" @default.
- W2155701384 countsByYear W21557013842015 @default.
- W2155701384 crossrefType "journal-article" @default.
- W2155701384 hasAuthorship W2155701384A5011441043 @default.
- W2155701384 hasAuthorship W2155701384A5012361101 @default.
- W2155701384 hasAuthorship W2155701384A5040672818 @default.
- W2155701384 hasAuthorship W2155701384A5042279691 @default.
- W2155701384 hasAuthorship W2155701384A5062232273 @default.
- W2155701384 hasAuthorship W2155701384A5065254374 @default.
- W2155701384 hasAuthorship W2155701384A5077354575 @default.
- W2155701384 hasAuthorship W2155701384A5084466098 @default.
- W2155701384 hasBestOaLocation W21557013841 @default.
- W2155701384 hasConcept C184235292 @default.
- W2155701384 hasConcept C185592680 @default.
- W2155701384 hasConcept C2780610907 @default.
- W2155701384 hasConcept C86803240 @default.
- W2155701384 hasConcept C95444343 @default.
- W2155701384 hasConcept C97029542 @default.
- W2155701384 hasConceptScore W2155701384C184235292 @default.
- W2155701384 hasConceptScore W2155701384C185592680 @default.
- W2155701384 hasConceptScore W2155701384C2780610907 @default.
- W2155701384 hasConceptScore W2155701384C86803240 @default.
- W2155701384 hasConceptScore W2155701384C95444343 @default.
- W2155701384 hasConceptScore W2155701384C97029542 @default.
- W2155701384 hasIssue "8" @default.
- W2155701384 hasLocation W21557013841 @default.
- W2155701384 hasOpenAccess W2155701384 @default.
- W2155701384 hasPrimaryLocation W21557013841 @default.
- W2155701384 hasRelatedWork W1550990988 @default.
- W2155701384 hasRelatedWork W1964622351 @default.
- W2155701384 hasRelatedWork W2000118052 @default.
- W2155701384 hasRelatedWork W2025794474 @default.
- W2155701384 hasRelatedWork W2116802979 @default.
- W2155701384 hasRelatedWork W2138421685 @default.
- W2155701384 hasRelatedWork W2188678043 @default.
- W2155701384 hasRelatedWork W2466884493 @default.
- W2155701384 hasRelatedWork W2477035600 @default.
- W2155701384 hasRelatedWork W2521771065 @default.
- W2155701384 hasVolume "16" @default.
- W2155701384 isParatext "false" @default.
- W2155701384 isRetracted "false" @default.
- W2155701384 magId "2155701384" @default.
- W2155701384 workType "article" @default.