Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155802351> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2155802351 abstract "The aim of this study was to develop and validate a prognostication model to predict overall and breast cancer specific survival for women treated for early breast cancer in the UK. Using the Eastern Cancer Registration and Information Centre (ECRIC) dataset, information was collated for 5,694 women who had surgery for invasive breast cancer in East Anglia from 1999 to 2003. Breast cancer mortality models for oestrogen receptor (ER) positive and ER negative tumours were derived from these data using Cox proportional hazards, adjusting for prognostic factors and mode of cancer detection (symptomatic versus screen-detected). An external dataset of 5,468 patients from the West Midlands Cancer Intelligence Unit (WMCIU) was used for validation. Differences in overall actual and predicted mortality were <1% at eight years for ECRIC (18.9% vs. 19.0%) and WMCIU (17.5% vs. 18.3%) with area under receiver-operator-characteristic curves (AUC) of 0.81 and 0.79 respectively. Differences in breast cancer specific actual and predicted mortality were <1% at eight years for ECRIC (12.9% vs. 13.5%) and <1.5% at eight years for WMCIU (12.2% vs. 13.6%) with AUC of 0.84 and 0.82 respectively. Model calibration was good for both ER positive and negative models although the ER positive model provided better discrimination (AUC 0.82) than ER negative (AUC 0.75). We have developed a prognostication model for early breast cancer based on UK cancer registry data that predicts breast cancer survival following surgery for invasive breast cancer and includes mode of detection for the first time. The model is well calibrated, provides a high degree of discrimination and has been validated in a second UK patient cohort." @default.
- W2155802351 created "2016-06-24" @default.
- W2155802351 creator A5012129899 @default.
- W2155802351 creator A5032413818 @default.
- W2155802351 creator A5062536828 @default.
- W2155802351 creator A5062977695 @default.
- W2155802351 creator A5067386487 @default.
- W2155802351 creator A5076118281 @default.
- W2155802351 creator A5078095859 @default.
- W2155802351 creator A5088178921 @default.
- W2155802351 date "2010-01-06" @default.
- W2155802351 modified "2023-10-14" @default.
- W2155802351 title "PREDICT: a new UK prognostic model that predicts survival following surgery for invasive breast cancer" @default.
- W2155802351 cites W1262485082 @default.
- W2155802351 cites W1562190372 @default.
- W2155802351 cites W1930298597 @default.
- W2155802351 cites W1974963731 @default.
- W2155802351 cites W1995318670 @default.
- W2155802351 cites W1996624321 @default.
- W2155802351 cites W1997756362 @default.
- W2155802351 cites W2033364004 @default.
- W2155802351 cites W2069869097 @default.
- W2155802351 cites W2074162144 @default.
- W2155802351 cites W2080057019 @default.
- W2155802351 cites W2097977223 @default.
- W2155802351 cites W2120065707 @default.
- W2155802351 cites W2171051298 @default.
- W2155802351 cites W2185055660 @default.
- W2155802351 doi "https://doi.org/10.1186/bcr2464" @default.
- W2155802351 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2880419" @default.
- W2155802351 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20053270" @default.
- W2155802351 hasPublicationYear "2010" @default.
- W2155802351 type Work @default.
- W2155802351 sameAs 2155802351 @default.
- W2155802351 citedByCount "274" @default.
- W2155802351 countsByYear W21558023512012 @default.
- W2155802351 countsByYear W21558023512013 @default.
- W2155802351 countsByYear W21558023512014 @default.
- W2155802351 countsByYear W21558023512015 @default.
- W2155802351 countsByYear W21558023512016 @default.
- W2155802351 countsByYear W21558023512017 @default.
- W2155802351 countsByYear W21558023512018 @default.
- W2155802351 countsByYear W21558023512019 @default.
- W2155802351 countsByYear W21558023512020 @default.
- W2155802351 countsByYear W21558023512021 @default.
- W2155802351 countsByYear W21558023512022 @default.
- W2155802351 countsByYear W21558023512023 @default.
- W2155802351 crossrefType "journal-article" @default.
- W2155802351 hasAuthorship W2155802351A5012129899 @default.
- W2155802351 hasAuthorship W2155802351A5032413818 @default.
- W2155802351 hasAuthorship W2155802351A5062536828 @default.
- W2155802351 hasAuthorship W2155802351A5062977695 @default.
- W2155802351 hasAuthorship W2155802351A5067386487 @default.
- W2155802351 hasAuthorship W2155802351A5076118281 @default.
- W2155802351 hasAuthorship W2155802351A5078095859 @default.
- W2155802351 hasAuthorship W2155802351A5088178921 @default.
- W2155802351 hasBestOaLocation W21558023511 @default.
- W2155802351 hasConcept C121608353 @default.
- W2155802351 hasConcept C126322002 @default.
- W2155802351 hasConcept C143998085 @default.
- W2155802351 hasConcept C2778527826 @default.
- W2155802351 hasConcept C2780140570 @default.
- W2155802351 hasConcept C29456083 @default.
- W2155802351 hasConcept C50382708 @default.
- W2155802351 hasConcept C530470458 @default.
- W2155802351 hasConcept C58471807 @default.
- W2155802351 hasConcept C71924100 @default.
- W2155802351 hasConceptScore W2155802351C121608353 @default.
- W2155802351 hasConceptScore W2155802351C126322002 @default.
- W2155802351 hasConceptScore W2155802351C143998085 @default.
- W2155802351 hasConceptScore W2155802351C2778527826 @default.
- W2155802351 hasConceptScore W2155802351C2780140570 @default.
- W2155802351 hasConceptScore W2155802351C29456083 @default.
- W2155802351 hasConceptScore W2155802351C50382708 @default.
- W2155802351 hasConceptScore W2155802351C530470458 @default.
- W2155802351 hasConceptScore W2155802351C58471807 @default.
- W2155802351 hasConceptScore W2155802351C71924100 @default.
- W2155802351 hasIssue "1" @default.
- W2155802351 hasLocation W21558023511 @default.
- W2155802351 hasLocation W21558023512 @default.
- W2155802351 hasLocation W21558023513 @default.
- W2155802351 hasLocation W21558023514 @default.
- W2155802351 hasLocation W21558023515 @default.
- W2155802351 hasOpenAccess W2155802351 @default.
- W2155802351 hasPrimaryLocation W21558023511 @default.
- W2155802351 hasRelatedWork W2113427382 @default.
- W2155802351 hasRelatedWork W2121904146 @default.
- W2155802351 hasRelatedWork W2954762607 @default.
- W2155802351 hasRelatedWork W3097583610 @default.
- W2155802351 hasRelatedWork W3163505858 @default.
- W2155802351 hasRelatedWork W3175662144 @default.
- W2155802351 hasRelatedWork W3193380953 @default.
- W2155802351 hasRelatedWork W4256227745 @default.
- W2155802351 hasRelatedWork W4289766408 @default.
- W2155802351 hasRelatedWork W3113313363 @default.
- W2155802351 hasVolume "12" @default.
- W2155802351 isParatext "false" @default.
- W2155802351 isRetracted "false" @default.
- W2155802351 magId "2155802351" @default.
- W2155802351 workType "article" @default.