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- W2155890847 endingPage "412" @default.
- W2155890847 startingPage "397" @default.
- W2155890847 abstract "Tendinopathy and osteoarthritis are common chronic musculoskeletal conditions that are associated with frequent pain and reduced function. With the advent of autologous platelet-rich plasma (PRP), new opportunities are available to elucidate potential healing mechanisms and elaborate safe injection therapies. PRP therapy involves the use of autologous activated platelets retained in fibrin matrices as a source of growth factors and cytokines that are active in healing mechanisms, such as inflammation, angiogenesis, cell migration and proliferation. Here we provide an overview of the main components of PRP products relevant to the mechanism of action in tendinopathy and osteoarthritis, and emphasize the importance of identifying and exploiting principal molecular components in PRP for therapeutic benefit. We review the clinical applications of PRP in osteoarthritis and tendinopathy and discuss the current existing challenges." @default.
- W2155890847 created "2016-06-24" @default.
- W2155890847 creator A5035023193 @default.
- W2155890847 creator A5070217909 @default.
- W2155890847 date "2012-08-01" @default.
- W2155890847 modified "2023-09-25" @default.
- W2155890847 title "Platelet-rich plasma injections for tendinopathy and osteoarthritis" @default.
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- W2155890847 doi "https://doi.org/10.2217/ijr.12.36" @default.
- W2155890847 hasPublicationYear "2012" @default.
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