FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155914867> ?p ?o ?g. }

• W2155914867 endingPage "333" @default.
• W2155914867 startingPage "323" @default.
• W2155914867 abstract "The significance of Streptococcus gordonii in dental caries is undefined, as is that of other alpha-amylase-binding bacteria (ABB) commonly found in the mouth. To clarify the ecological and cariological roles of S. gordonii our specific pathogen-free Osborne-Mendel rats, TAN:SPFOM(OM)BR, were fed either diet 2000 (containing 56% confectioner's sugar, most of which is sucrose) or diet 2000CS (containing 56% cornstarch, in lieu of confectioner's sugar) and inoculated with S. gordonii strains. Uninoculated rats were free of both indigenous mutans streptococci (MS) and ABB, including S. gordonii, as shown by culture on mitis salivarius and blood agars of swabs and sonicates of dentitions after weanlings had consumed these diets for 26 days. ABB were detected by radiochemical assay using [125I]-amylase reactive to alpha-amylase-binding protein characteristic of the surface of S. gordonii and other ABB. No ABB were detected (detection limit < 1 colony-forming units in 10(6) colony-forming units). Thus the TAN:SPFOM(OM)BR colony presents a 'clean animal model' for subsequent study. Consequently, S. gordonii strains Challis or G9B were used to inoculate weanling rat groups consuming either the high-sucrose diet 2000 or the cornstarch diet 2000CS. Two additional groups fed each of these diets remained unioculated. Recoveries of inoculants were tested 12 and 26 days later by oral swabs and sonication of the molars of one hemimandible of each animal, respectively. Uninoculated animals were reconfirmed to be free of ABB and mutans streptococci, but inoculated ones eating diet 2000CS had S. gordonii recoveries of 1-10% or, if eating diet 2000, 10-30% of total colony-farming units in sonicates. There were no statistically significant differences among the inoculated and uninoculated animal groups' caries scores when they ate the cornstarch diet. Lesion scores for sucrose-eating rats were, however, from 2.4-5.1-fold higher than for cornstarch-eating rats, P < 0.001, and were still higher if animals had been inoculated with either Challis (1.41-fold) or G9B (1.64-fold), than if uninoculated, both P < 0.001, so long as the rats ate the sucrose diet. Therefore, TAN:SPFOM(OM)BR rats do not harbour ABB or S. gordonii but can be colonized by S. gordonii. Colonization levels of S. gordonii on the teeth are higher in the presence of high sucrose than with high starch-containing diets. Caries scores are augmented by sucrose compared with starch, and are further augmented by S gordonii colonization. S. gordonii is thus cariologically significant in the presence of sucrose, at least in this rat." @default.
• W2155914867 created "2016-06-24" @default.
• W2155914867 creator A5034197049 @default.
• W2155914867 creator A5062689993 @default.
• W2155914867 creator A5063628247 @default.
• W2155914867 creator A5074956943 @default.
• W2155914867 creator A5075008449 @default.
• W2155914867 date "2001-04-01" @default.
• W2155914867 modified "2023-10-13" @default.
• W2155914867 title "Oral colonization and cariogenicity of Streptococcus gordonii in specific pathogen-free TAN:SPFOM(OM)BR rats consuming starch or sucrose diets" @default.
• W2155914867 cites W1513574207 @default.
• W2155914867 cites W1570561206 @default.
• W2155914867 cites W1574513612 @default.
• W2155914867 cites W1584241653 @default.
• W2155914867 cites W1791213010 @default.
• W2155914867 cites W1824393454 @default.
• W2155914867 cites W1852738564 @default.
• W2155914867 cites W1855040068 @default.
• W2155914867 cites W1857771815 @default.
• W2155914867 cites W1888911165 @default.
• W2155914867 cites W1891891375 @default.
• W2155914867 cites W1902737891 @default.
• W2155914867 cites W1927379896 @default.
• W2155914867 cites W1930778760 @default.
• W2155914867 cites W1932189699 @default.
• W2155914867 cites W1947525750 @default.
• W2155914867 cites W1955252499 @default.
• W2155914867 cites W1973192271 @default.
• W2155914867 cites W1974831325 @default.
• W2155914867 cites W1991638060 @default.
• W2155914867 cites W1997715698 @default.
• W2155914867 cites W2000861470 @default.
• W2155914867 cites W2002549311 @default.
• W2155914867 cites W2019026081 @default.
• W2155914867 cites W2019081862 @default.
• W2155914867 cites W2025966124 @default.
• W2155914867 cites W2032085627 @default.
• W2155914867 cites W2033294077 @default.
• W2155914867 cites W2041606886 @default.
• W2155914867 cites W2047997763 @default.
• W2155914867 cites W2064203917 @default.
• W2155914867 cites W2064335440 @default.
• W2155914867 cites W2064548129 @default.
• W2155914867 cites W2065630352 @default.
• W2155914867 cites W2068227566 @default.
• W2155914867 cites W2069293004 @default.
• W2155914867 cites W2071147748 @default.
• W2155914867 cites W2077117648 @default.
• W2155914867 cites W2085116235 @default.
• W2155914867 cites W2091204599 @default.
• W2155914867 cites W2102758460 @default.
• W2155914867 cites W2108243647 @default.
• W2155914867 cites W2113611201 @default.
• W2155914867 cites W2116108626 @default.
• W2155914867 cites W2125180103 @default.
• W2155914867 cites W2125603375 @default.
• W2155914867 cites W2144961182 @default.
• W2155914867 cites W2145477141 @default.
• W2155914867 cites W2145645349 @default.
• W2155914867 cites W2150513219 @default.
• W2155914867 cites W2153657196 @default.
• W2155914867 cites W2163829996 @default.
• W2155914867 cites W2164667642 @default.
• W2155914867 cites W2168261110 @default.
• W2155914867 cites W2205009002 @default.
• W2155914867 cites W2416674597 @default.
• W2155914867 cites W2419843077 @default.
• W2155914867 cites W2609421105 @default.
• W2155914867 cites W4238151014 @default.
• W2155914867 cites W4254344082 @default.
• W2155914867 cites W1971872667 @default.
• W2155914867 doi "https://doi.org/10.1016/s0003-9969(00)00126-6" @default.
• W2155914867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11269866" @default.
• W2155914867 hasPublicationYear "2001" @default.
• W2155914867 type Work @default.
• W2155914867 sameAs 2155914867 @default.
• W2155914867 citedByCount "28" @default.
• W2155914867 countsByYear W21559148672012 @default.
• W2155914867 countsByYear W21559148672013 @default.
• W2155914867 countsByYear W21559148672014 @default.
• W2155914867 countsByYear W21559148672015 @default.
• W2155914867 countsByYear W21559148672017 @default.
• W2155914867 countsByYear W21559148672018 @default.
• W2155914867 countsByYear W21559148672022 @default.
• W2155914867 crossrefType "journal-article" @default.
• W2155914867 hasAuthorship W2155914867A5034197049 @default.
• W2155914867 hasAuthorship W2155914867A5062689993 @default.
• W2155914867 hasAuthorship W2155914867A5063628247 @default.
• W2155914867 hasAuthorship W2155914867A5074956943 @default.
• W2155914867 hasAuthorship W2155914867A5075008449 @default.
• W2155914867 hasConcept C170835558 @default.
• W2155914867 hasConcept C180032290 @default.
• W2155914867 hasConcept C181199279 @default.
• W2155914867 hasConcept C185592680 @default.
• W2155914867 hasConcept C203014093 @default.
• W2155914867 hasConcept C2776460866 @default.
• W2155914867 hasConcept C2777858569 @default.
• W2155914867 hasConcept C2778430296 @default.

• next