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- W2155928171 abstract "Three simple S pectrophotometric methods have been developed for simultaneous estimation of Ci profloxacin and Ornidazole from tablet dosage form. Method A is Dual wavelength method, involves determination of Ciprofloxacin at the absorbance difference between 261.0 nm and 280.2 nm and ornidazole at the absorbance difference between 302.5 nm and 335 nm. Method B is First order derivative spectroscopy, wavelength selecte d for quantitation were 262 nm for Ciprofloxacin (zero cross for Ornidazole) and 332 nm for Ornidazole (ze ro cross for Ciprofloxacin). Method C is Area under Curve method; AUC in the range of 268.0 - 274.0 nm (for Ciprofloxacin) and 316.0 - 322.0 nm (for Ornidazole) were selected for the analysis. The linearity lies between 2 - 10 μg / ml and 2 – 20 μg / ml for Ciprofloxacin and Ornidazole respectively for Method A, B and C. The accuracy and precision of the methods were determined and validated statically. All the methods showed good reproducibility and recovery with low % RSD. Keywo rds : Ciprofloxacin, Ornidazole, Dual wavelength Method, First order derivative Spectroscopy, Area under curve method." @default.
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- W2155928171 date "2013-08-10" @default.
- W2155928171 modified "2023-09-27" @default.
- W2155928171 title "UV SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION OF SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN AND ORNIDAZOLE IN TABLET DOSAGE FORM" @default.
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- W2155928171 doi "https://doi.org/10.7897/2230-8407.04739" @default.
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