FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155953944> ?p ?o ?g. }

• W2155953944 endingPage "3058" @default.
• W2155953944 startingPage "3054" @default.
• W2155953944 abstract "We have purified an acidic octapeptide from the neural ganglion of the protochordate Ciona intestinalis by a three-step procedure including C18 Sep-Pak fractionation, MonoQ ion-exchange chromatography, and C4 reversed-phase high-performance liquid chromatography. The purification was monitored by an immunoassay specific for the alpha-carboxyamidated COOH terminus common to the mammalian brain-gut hormones, cholecystokinin and gastrin. Automated Edman degradation revealed the sequence Asn-Tyr-Tyr-Gly-Trp-Met-Asp-Phe. In accordance with the high acidity of the peptide, amino acid analysis after cleavage with aminopeptidase M showed that both tyrosyl residues are sulfated. Hence, the structure is Asn-Tyr(SO3)-Tyr(SO3)-Gly-Trp-Met-Asp-Phe-NH2, as also confirmed by identity with the synthetic disulfated peptide in different chromatographic systems. The occurrence of two consecutively sulfated tyrosyl residues after a neutral residue challenges present concepts of consensus sites for tyrosyl sulfation. We conclude that the structure of the peptide, named cionin, suits that of a common ancestor for cholecystokinin and gastrin." @default.
• W2155953944 created "2016-06-24" @default.
• W2155953944 creator A5025006519 @default.
• W2155953944 creator A5091673364 @default.
• W2155953944 date "1990-02-01" @default.
• W2155953944 modified "2023-10-01" @default.
• W2155953944 title "Cionin: a disulfotyrosyl hybrid of cholecystokinin and gastrin from the neural ganglion of the protochordate Ciona intestinalis." @default.
• W2155953944 cites W10230571 @default.
• W2155953944 cites W1505096168 @default.
• W2155953944 cites W1597868922 @default.
• W2155953944 cites W1682371140 @default.
• W2155953944 cites W1970773547 @default.
• W2155953944 cites W1988441601 @default.
• W2155953944 cites W1989507693 @default.
• W2155953944 cites W1997838746 @default.
• W2155953944 cites W2006043909 @default.
• W2155953944 cites W2006055734 @default.
• W2155953944 cites W2009233266 @default.
• W2155953944 cites W2029050852 @default.
• W2155953944 cites W2049569292 @default.
• W2155953944 cites W2056087565 @default.
• W2155953944 cites W2061354172 @default.
• W2155953944 cites W2061797080 @default.
• W2155953944 cites W2074955985 @default.
• W2155953944 cites W2076250903 @default.
• W2155953944 cites W2082261438 @default.
• W2155953944 cites W2126149194 @default.
• W2155953944 cites W2171144808 @default.
• W2155953944 cites W2177863533 @default.
• W2155953944 cites W2326832967 @default.
• W2155953944 doi "https://doi.org/10.1016/s0021-9258(19)39732-7" @default.
• W2155953944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2303439" @default.
• W2155953944 hasPublicationYear "1990" @default.
• W2155953944 type Work @default.
• W2155953944 sameAs 2155953944 @default.
• W2155953944 citedByCount "119" @default.
• W2155953944 countsByYear W21559539442012 @default.
• W2155953944 countsByYear W21559539442013 @default.
• W2155953944 countsByYear W21559539442014 @default.
• W2155953944 countsByYear W21559539442015 @default.
• W2155953944 countsByYear W21559539442016 @default.
• W2155953944 countsByYear W21559539442017 @default.
• W2155953944 countsByYear W21559539442018 @default.
• W2155953944 countsByYear W21559539442019 @default.
• W2155953944 countsByYear W21559539442020 @default.
• W2155953944 countsByYear W21559539442021 @default.
• W2155953944 countsByYear W21559539442022 @default.
• W2155953944 countsByYear W21559539442023 @default.
• W2155953944 crossrefType "journal-article" @default.
• W2155953944 hasAuthorship W2155953944A5025006519 @default.
• W2155953944 hasAuthorship W2155953944A5091673364 @default.
• W2155953944 hasBestOaLocation W21559539441 @default.
• W2155953944 hasConcept C104317684 @default.
• W2155953944 hasConcept C105702510 @default.
• W2155953944 hasConcept C126322002 @default.
• W2155953944 hasConcept C134018914 @default.
• W2155953944 hasConcept C170493617 @default.
• W2155953944 hasConcept C185592680 @default.
• W2155953944 hasConcept C2776986829 @default.
• W2155953944 hasConcept C2777593968 @default.
• W2155953944 hasConcept C2777951760 @default.
• W2155953944 hasConcept C2779528156 @default.
• W2155953944 hasConcept C2781334511 @default.
• W2155953944 hasConcept C49039625 @default.
• W2155953944 hasConcept C55493867 @default.
• W2155953944 hasConcept C56191518 @default.
• W2155953944 hasConcept C71315377 @default.
• W2155953944 hasConcept C71924100 @default.
• W2155953944 hasConcept C86803240 @default.
• W2155953944 hasConceptScore W2155953944C104317684 @default.
• W2155953944 hasConceptScore W2155953944C105702510 @default.
• W2155953944 hasConceptScore W2155953944C126322002 @default.
• W2155953944 hasConceptScore W2155953944C134018914 @default.
• W2155953944 hasConceptScore W2155953944C170493617 @default.
• W2155953944 hasConceptScore W2155953944C185592680 @default.
• W2155953944 hasConceptScore W2155953944C2776986829 @default.
• W2155953944 hasConceptScore W2155953944C2777593968 @default.
• W2155953944 hasConceptScore W2155953944C2777951760 @default.
• W2155953944 hasConceptScore W2155953944C2779528156 @default.
• W2155953944 hasConceptScore W2155953944C2781334511 @default.
• W2155953944 hasConceptScore W2155953944C49039625 @default.
• W2155953944 hasConceptScore W2155953944C55493867 @default.
• W2155953944 hasConceptScore W2155953944C56191518 @default.
• W2155953944 hasConceptScore W2155953944C71315377 @default.
• W2155953944 hasConceptScore W2155953944C71924100 @default.
• W2155953944 hasConceptScore W2155953944C86803240 @default.
• W2155953944 hasIssue "6" @default.
• W2155953944 hasLocation W21559539441 @default.
• W2155953944 hasOpenAccess W2155953944 @default.
• W2155953944 hasPrimaryLocation W21559539441 @default.
• W2155953944 hasRelatedWork W1982594208 @default.
• W2155953944 hasRelatedWork W2015597507 @default.
• W2155953944 hasRelatedWork W2020426708 @default.
• W2155953944 hasRelatedWork W2031272904 @default.
• W2155953944 hasRelatedWork W2065950538 @default.
• W2155953944 hasRelatedWork W2069633620 @default.
• W2155953944 hasRelatedWork W2086389855 @default.
• W2155953944 hasRelatedWork W2417190956 @default.

• next