FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155969246> ?p ?o ?g. }

• W2155969246 endingPage "820" @default.
• W2155969246 startingPage "814" @default.
• W2155969246 abstract "The pedunculopontine nucleus (PPN) region of the brainstem has become a new stimulation target for the treatment of gait freezing, akinesia, and postural instability in advanced Parkinson disease (PD). Because PD locomotor symptoms are probably caused by excessive gamma-aminobutyric acidergic inhibition of the PPN, low-frequency stimulation of the PPN may overcome this inhibition and improve the symptoms. However, the anatomical connections of this region in humans are not known in any detail.Diffusion weighted magnetic resonance (MR) images were acquired at 1.5 teslas, and probabilistic tractography was used to trace the connections of the PPN region in eight healthy volunteers. A single seed voxel (2 x 2 x 2 mm) was chosen in the PPN just lateral to the decussation of the superior cerebellar peduncle, and the Diffusion Toolbox of the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain was used to process the acquired MR images. The connections of each volunteer's PPN region were analyzed using a human brain MR imaging atlas.The PPN region was connected with the cerebellum and spinal cord below and to the thalamus, pallidum, subthalamic nucleus, and motor cortex above. The regions of the primary motor cortex that control the trunk and upper and lower extremities had the highest connectivity compared with other parts of motor cortex.These findings suggest that connections of the PPN region with the primary motor cortex, basal ganglia, thalamus, cerebellum, and spinal cord may play important roles in the regulation of movement by the PPN region. Diffusion tensor imaging tractography of the PPN region may be used preoperatively to optimize placement of stimulation electrodes and postoperatively it may also be useful to reassess electrode positions." @default.
• W2155969246 created "2016-06-24" @default.
• W2155969246 creator A5000769091 @default.
• W2155969246 creator A5030823525 @default.
• W2155969246 creator A5031648152 @default.
• W2155969246 creator A5031742616 @default.
• W2155969246 creator A5033360475 @default.
• W2155969246 creator A5043559110 @default.
• W2155969246 creator A5073459233 @default.
• W2155969246 creator A5082796625 @default.
• W2155969246 date "2007-10-01" @default.
• W2155969246 modified "2023-09-24" @default.
• W2155969246 title "Connectivity of the human pedunculopontine nucleus region and diffusion tensor imaging in surgical targeting" @default.
• W2155969246 cites W1963929973 @default.
• W2155969246 cites W1964236968 @default.
• W2155969246 cites W1965731226 @default.
• W2155969246 cites W1967472878 @default.
• W2155969246 cites W1977799117 @default.
• W2155969246 cites W1983077460 @default.
• W2155969246 cites W1985698740 @default.
• W2155969246 cites W1985837606 @default.
• W2155969246 cites W1996638302 @default.
• W2155969246 cites W2000569019 @default.
• W2155969246 cites W2002581100 @default.
• W2155969246 cites W2007501328 @default.
• W2155969246 cites W2010808187 @default.
• W2155969246 cites W2011576378 @default.
• W2155969246 cites W2014844540 @default.
• W2155969246 cites W2016033342 @default.
• W2155969246 cites W2022530159 @default.
• W2155969246 cites W2022997759 @default.
• W2155969246 cites W2023196735 @default.
• W2155969246 cites W2027947474 @default.
• W2155969246 cites W2028942474 @default.
• W2155969246 cites W2029409525 @default.
• W2155969246 cites W2032376916 @default.
• W2155969246 cites W2033363720 @default.
• W2155969246 cites W2035758399 @default.
• W2155969246 cites W2050537245 @default.
• W2155969246 cites W2052570168 @default.
• W2155969246 cites W2053476190 @default.
• W2155969246 cites W2053773527 @default.
• W2155969246 cites W2063001897 @default.
• W2155969246 cites W2065274468 @default.
• W2155969246 cites W2066016314 @default.
• W2155969246 cites W2069317710 @default.
• W2155969246 cites W2073827784 @default.
• W2155969246 cites W2077934352 @default.
• W2155969246 cites W2078011569 @default.
• W2155969246 cites W2079041835 @default.
• W2155969246 cites W2080414043 @default.
• W2155969246 cites W2084621470 @default.
• W2155969246 cites W2087890883 @default.
• W2155969246 cites W2093237730 @default.
• W2155969246 cites W2102479862 @default.
• W2155969246 cites W2105848810 @default.
• W2155969246 cites W2106108170 @default.
• W2155969246 cites W2113383710 @default.
• W2155969246 cites W2116136260 @default.
• W2155969246 cites W2124540951 @default.
• W2155969246 cites W2142059961 @default.
• W2155969246 cites W2145132952 @default.
• W2155969246 cites W2148726987 @default.
• W2155969246 cites W2151364442 @default.
• W2155969246 cites W2156715960 @default.
• W2155969246 cites W2170596158 @default.
• W2155969246 cites W2334348929 @default.
• W2155969246 doi "https://doi.org/10.3171/jns-07/10/0814" @default.
• W2155969246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17937229" @default.
• W2155969246 hasPublicationYear "2007" @default.
• W2155969246 type Work @default.
• W2155969246 sameAs 2155969246 @default.
• W2155969246 citedByCount "109" @default.
• W2155969246 countsByYear W21559692462012 @default.
• W2155969246 countsByYear W21559692462013 @default.
• W2155969246 countsByYear W21559692462014 @default.
• W2155969246 countsByYear W21559692462015 @default.
• W2155969246 countsByYear W21559692462016 @default.
• W2155969246 countsByYear W21559692462017 @default.
• W2155969246 countsByYear W21559692462018 @default.
• W2155969246 countsByYear W21559692462019 @default.
• W2155969246 countsByYear W21559692462020 @default.
• W2155969246 countsByYear W21559692462021 @default.
• W2155969246 countsByYear W21559692462022 @default.
• W2155969246 countsByYear W21559692462023 @default.
• W2155969246 crossrefType "journal-article" @default.
• W2155969246 hasAuthorship W2155969246A5000769091 @default.
• W2155969246 hasAuthorship W2155969246A5030823525 @default.
• W2155969246 hasAuthorship W2155969246A5031648152 @default.
• W2155969246 hasAuthorship W2155969246A5031742616 @default.
• W2155969246 hasAuthorship W2155969246A5033360475 @default.
• W2155969246 hasAuthorship W2155969246A5043559110 @default.
• W2155969246 hasAuthorship W2155969246A5073459233 @default.
• W2155969246 hasAuthorship W2155969246A5082796625 @default.
• W2155969246 hasConcept C105702510 @default.
• W2155969246 hasConcept C126838900 @default.
• W2155969246 hasConcept C142724271 @default.
• W2155969246 hasConcept C143409427 @default.

• next