FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2155991810> ?p ?o ?g. }

• W2155991810 endingPage "320" @default.
• W2155991810 startingPage "313" @default.
• W2155991810 abstract "Previous studies have shown that lumican is expressed and increased in the stroma of breast tumours. Lumican expression has now been examined relative to other members of the small leucine-rich proteoglycan gene family in normal and neoplastic breast tissues, to begin to determine its role in breast tumour progression. Western blot study showed that lumican protein is highly abundant relative to decorin, while biglycan and fibromodulin are only detected occasionally in breast tissues (n=15 cases). Further analysis of lumican and decorin expression performed in matched normal and tumour tissues by in situ hybridization showed that both mRNAs were expressed by similar fibroblast-like cells adjacent to epithelium. However, lumican mRNA expression was significantly increased in tumours (n=34, p<0.0001), while decorin mRNA was decreased (p=0.0002) in neoplastic relative to adjacent normal stroma. This was accompanied by a significant increase in lumican protein (n=12, p=0.0122), but not decorin. Further evidence of altered lumican expression in breast cancer was manifested by discordance between lumican mRNA and protein localization in some regions of tumours but not in adjacent morphologically normal tissues. It is concluded that lumican is the most abundant of these proteoglycans in breast tumours and that lumican and decorin are inversely regulated in association with breast tumourigenesis." @default.
• W2155991810 created "2016-06-24" @default.
• W2155991810 creator A5002527454 @default.
• W2155991810 creator A5019623844 @default.
• W2155991810 creator A5027173170 @default.
• W2155991810 creator A5054903643 @default.
• W2155991810 creator A5055090415 @default.
• W2155991810 creator A5057609330 @default.
• W2155991810 creator A5062187128 @default.
• W2155991810 creator A5084375700 @default.
• W2155991810 date "2000-01-01" @default.
• W2155991810 modified "2023-10-16" @default.
• W2155991810 title "Lumican and decorin are differentially expressed in human breast carcinoma" @default.
• W2155991810 cites W1521898800 @default.
• W2155991810 cites W1650984530 @default.
• W2155991810 cites W1972571287 @default.
• W2155991810 cites W2009212790 @default.
• W2155991810 cites W2023104790 @default.
• W2155991810 cites W2031354590 @default.
• W2155991810 cites W2036341761 @default.
• W2155991810 cites W2037480666 @default.
• W2155991810 cites W2038879917 @default.
• W2155991810 cites W2041988832 @default.
• W2155991810 cites W2043884900 @default.
• W2155991810 cites W2047578760 @default.
• W2155991810 cites W2057297291 @default.
• W2155991810 cites W2070013317 @default.
• W2155991810 cites W2070669362 @default.
• W2155991810 cites W2075073611 @default.
• W2155991810 cites W208674030 @default.
• W2155991810 cites W2090603283 @default.
• W2155991810 cites W2092705117 @default.
• W2155991810 cites W2099306749 @default.
• W2155991810 cites W2130415027 @default.
• W2155991810 cites W2131687641 @default.
• W2155991810 cites W2141877739 @default.
• W2155991810 cites W2159058635 @default.
• W2155991810 cites W2418674098 @default.
• W2155991810 cites W35887883 @default.
• W2155991810 doi "https://doi.org/10.1002/1096-9896(200011)192:3<313::aid-path694>3.0.co;2-b" @default.
• W2155991810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11054714" @default.
• W2155991810 hasPublicationYear "2000" @default.
• W2155991810 type Work @default.
• W2155991810 sameAs 2155991810 @default.
• W2155991810 citedByCount "133" @default.
• W2155991810 countsByYear W21559918102012 @default.
• W2155991810 countsByYear W21559918102013 @default.
• W2155991810 countsByYear W21559918102014 @default.
• W2155991810 countsByYear W21559918102015 @default.
• W2155991810 countsByYear W21559918102016 @default.
• W2155991810 countsByYear W21559918102017 @default.
• W2155991810 countsByYear W21559918102018 @default.
• W2155991810 countsByYear W21559918102019 @default.
• W2155991810 countsByYear W21559918102020 @default.
• W2155991810 countsByYear W21559918102021 @default.
• W2155991810 countsByYear W21559918102022 @default.
• W2155991810 crossrefType "journal-article" @default.
• W2155991810 hasAuthorship W2155991810A5002527454 @default.
• W2155991810 hasAuthorship W2155991810A5019623844 @default.
• W2155991810 hasAuthorship W2155991810A5027173170 @default.
• W2155991810 hasAuthorship W2155991810A5054903643 @default.
• W2155991810 hasAuthorship W2155991810A5055090415 @default.
• W2155991810 hasAuthorship W2155991810A5057609330 @default.
• W2155991810 hasAuthorship W2155991810A5062187128 @default.
• W2155991810 hasAuthorship W2155991810A5084375700 @default.
• W2155991810 hasConcept C121608353 @default.
• W2155991810 hasConcept C142724271 @default.
• W2155991810 hasConcept C153911025 @default.
• W2155991810 hasConcept C189165786 @default.
• W2155991810 hasConcept C203014093 @default.
• W2155991810 hasConcept C204232928 @default.
• W2155991810 hasConcept C2778916964 @default.
• W2155991810 hasConcept C2779335624 @default.
• W2155991810 hasConcept C2779457992 @default.
• W2155991810 hasConcept C2779794767 @default.
• W2155991810 hasConcept C52124034 @default.
• W2155991810 hasConcept C530470458 @default.
• W2155991810 hasConcept C54355233 @default.
• W2155991810 hasConcept C71924100 @default.
• W2155991810 hasConcept C86803240 @default.
• W2155991810 hasConcept C95444343 @default.
• W2155991810 hasConceptScore W2155991810C121608353 @default.
• W2155991810 hasConceptScore W2155991810C142724271 @default.
• W2155991810 hasConceptScore W2155991810C153911025 @default.
• W2155991810 hasConceptScore W2155991810C189165786 @default.
• W2155991810 hasConceptScore W2155991810C203014093 @default.
• W2155991810 hasConceptScore W2155991810C204232928 @default.
• W2155991810 hasConceptScore W2155991810C2778916964 @default.
• W2155991810 hasConceptScore W2155991810C2779335624 @default.
• W2155991810 hasConceptScore W2155991810C2779457992 @default.
• W2155991810 hasConceptScore W2155991810C2779794767 @default.
• W2155991810 hasConceptScore W2155991810C52124034 @default.
• W2155991810 hasConceptScore W2155991810C530470458 @default.
• W2155991810 hasConceptScore W2155991810C54355233 @default.
• W2155991810 hasConceptScore W2155991810C71924100 @default.
• W2155991810 hasConceptScore W2155991810C86803240 @default.
• W2155991810 hasConceptScore W2155991810C95444343 @default.
• W2155991810 hasIssue "3" @default.

• next