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• W2156121268 abstract "Enzymatic aurification: The first asymmetric synthesis of the antiproliferative and antifungal pyrone metabolite (+)-(R)-aureothin (1) from Streptomyces thioluteus was completed by taking advantage of synergy of synthetic and enzymatic transformations. Synthetic vinyl iodide 14 was regioselectively methylated by AurI prior to asymmetric heterocyclization catalyzed by the bifunctional monooxygenase AurH and Stille coupling. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2268/2008/z800301_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
• W2156121268 created "2016-06-24" @default.
• W2156121268 creator A5056979790 @default.
• W2156121268 creator A5066230640 @default.
• W2156121268 date "2008-08-27" @default.
• W2156121268 modified "2023-10-17" @default.
• W2156121268 title "Chemoenzymatic Total Synthesis of the Antiproliferative Polyketide (+)-(<i>R</i>)-Aureothin" @default.
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• W2156121268 doi "https://doi.org/10.1002/cbic.200800301" @default.
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