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• W2156187777 endingPage "282" @default.
• W2156187777 startingPage "275" @default.
• W2156187777 abstract "New 5-aryl-10-(4-(4-methoxyphenyl)thiazole-2-yl)-9,10-dihydropyrido[2,3-d:5,6-d']dipyrimidinone-2,4,6,8-(1H,3H,5H,7H)-tetraones 6a-d were synthesized through one-pot four-component reaction of aldehydes, barbituric acid, and thiazole using Zn(2+) @KSF under reflux condition. The key features of this reaction are: incorporating four heterocyclic rings, using a heterogeneous and efficient catalyst, high yield, and easy-to-setup reaction. The structure of the products was confirmed by FT-IR, (1)H NMR, and (13)C NMR spectra. The antibacterial activities of compounds 6a-d were screened against Escherichia coli, Micrococcus luteus, Pseudomonas aeruginosa, and Staphylococcus aureus bacterial strains using the zone inhibition method. Also, the 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities of compounds 6a-d were evaluated. All compounds showed good antioxidant capacity in comparison to ascorbic acid. The IC50 values of the antioxidant activity were calculated. The proposed mechanism for antioxidant activity is discussed." @default.
• W2156187777 created "2016-06-24" @default.
• W2156187777 creator A5002877293 @default.
• W2156187777 creator A5075641042 @default.
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• W2156187777 date "2015-02-24" @default.
• W2156187777 modified "2023-10-10" @default.
• W2156187777 title "One-Pot Multi-Component Synthesis of 1,4-Dihydropyridines Using Zn²⁺@KSF and Evaluating Their Antibacterial and Antioxidant Activities" @default.
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• W2156187777 doi "https://doi.org/10.1002/ardp.201400414" @default.
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• W2156187777 hasPublicationYear "2015" @default.
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