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• W2156197542 abstract "To compare genotypic and phenotypic HIV-1 drug resistance assays.Protease inhibitor (PI) susceptibility was phenotypically analysed in HIV-1 isolates and recombinant viruses expressing proteases from viral isolates. Two genotypic interpretation methods were carried out in parallel.Entirely concordant resistance levels were shown in 5/10 (50%) highly active anti-retroviral therapy (HAART)-experienced patients, whereas minor discrepancies were observed in the remaining five patients.The four assays provide comparable results. The recombinant virus phenotypic assay may provide the most accurate evaluation of resistance; however, genotypic interpretation procedures are helpful for daily therapeutic decisions." @default.
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• W2156197542 date "2002-11-28" @default.
• W2156197542 modified "2023-10-14" @default.
• W2156197542 title "Comparison of levels of HIV-1 resistance to protease inhibitors by recombinant versus conventional virus phenotypic assay and two genotypic interpretation procedures in treatment-naive and HAART-experienced HIV-infected patients" @default.
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• W2156197542 doi "https://doi.org/10.1093/jac/dkg016" @default.
• W2156197542 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12493798" @default.
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