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- W2156212005 abstract "Antiretroviral therapy (ART) has converted human immunodeficiency virus (HIV) infection into a chronic condition, and patients now undergo a variety of surgical procedures, but current surgical outcomes are inadequately characterized.To compare 30-day postoperative mortality in patients with HIV infection receiving ART with the rates in uninfected individuals.Retrospective analysis of nationwide electronic medical record data from the US Veterans Health Administration Healthcare System, October 1, 1996, to September 30, 2010. Common inpatient surgical procedures were grouped using the Healthcare Cost and Utilization Project Clinical Classification System to match HIV-infected and uninfected patients in a 1:2 ratio. Data on 1641 patients with HIV infection receiving combination ART who were undergoing inpatient surgery were compared with data on 3282 procedure-matched, uninfected comparators. Poisson regression models of 30-day postoperative mortality were adjusted for procedure year, age, Charlson Comorbidity Index score, hemoglobin level, albumin level, HIV infection, CD4 cell count, and HIV-1 RNA level.All-cause 30-day postoperative mortality.The most common procedures in both groups were cholecystectomy (10.5%), hip arthroplasty (10.5%), spine surgery (9.8%), herniorrhaphy (7.4%), and coronary artery bypass grafting (7.0%). In patients with HIV infection, CD4 cell distributions were 80.0% with 200/μL or more, 16.3% with 50/μL to 199/μL, and 3.7% with less than 50/μL; 74.1% of patients with HIV infection had undetectable HIV-1 RNA. Human immunodeficiency virus infection was associated with higher 30-day postoperative mortality compared with the mortality in uninfected patients (3.4% [56 patients]) vs 1.6% [53]); incidence rate ratio [IRR], 2.11; 95% CI, 1.41-3.17; P < .001). CD4 cell count was inversely associated with mortality, but HIV-1 RNA provided no additional information. After adjustment, patients with HIV infection had increased mortality compared with uninfected patients at all CD4 cell count strata (≥500/μL: IRR, 1.92; 95% CI, 1.02-3.60; P = .04; 200-499/μL: IRR, 1.89; 95% CI, 1.20-2.98; P = .01; 50-199/μL: IRR, 2.66; 95% CI, 1.29-5.47; P = .01; and <50/μL: IRR, 6.21; 95% CI, 3.55-10.85; P < .001). Hypoalbuminemia (IRR, 4.35; 95% CI, 2.78-6.81; P < .001) and age in decades (IRR, 1.47; 95% CI, 1.23-1.76; P < .001) were also strongly associated with mortality.Current postoperative mortality rates among individuals with HIV infection who are receiving ART are low and are influenced as much by hypoalbuminemia and age as by CD4 cell status. Human immunodeficiency virus infection and CD4 cell count are only 2 of many factors associated with surgical outcomes that should be incorporated into surgical decision making." @default.
- W2156212005 created "2016-06-24" @default.
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- W2156212005 date "2015-04-01" @default.
- W2156212005 modified "2023-10-18" @default.
- W2156212005 title "Thirty-Day Postoperative Mortality Among Individuals With HIV Infection Receiving Antiretroviral Therapy and Procedure-Matched, Uninfected Comparators" @default.
- W2156212005 cites W1480136024 @default.
- W2156212005 cites W1547708675 @default.
- W2156212005 cites W1568613408 @default.
- W2156212005 cites W19572578 @default.
- W2156212005 cites W1965190768 @default.
- W2156212005 cites W1966466467 @default.
- W2156212005 cites W1972081722 @default.
- W2156212005 cites W1973048381 @default.
- W2156212005 cites W1976726571 @default.
- W2156212005 cites W1979573803 @default.
- W2156212005 cites W1983392806 @default.
- W2156212005 cites W1988116008 @default.
- W2156212005 cites W1989681781 @default.
- W2156212005 cites W1990238390 @default.
- W2156212005 cites W1992911253 @default.
- W2156212005 cites W1994397957 @default.
- W2156212005 cites W1995332295 @default.
- W2156212005 cites W1996434798 @default.
- W2156212005 cites W2000211970 @default.
- W2156212005 cites W2000445173 @default.
- W2156212005 cites W2007359807 @default.
- W2156212005 cites W2009308652 @default.
- W2156212005 cites W2009962304 @default.
- W2156212005 cites W2010430808 @default.
- W2156212005 cites W2010743390 @default.
- W2156212005 cites W2020513067 @default.
- W2156212005 cites W2022786711 @default.
- W2156212005 cites W2024959348 @default.
- W2156212005 cites W2025304598 @default.
- W2156212005 cites W2032031439 @default.
- W2156212005 cites W2033378093 @default.
- W2156212005 cites W2040079222 @default.
- W2156212005 cites W2049747948 @default.
- W2156212005 cites W2053178989 @default.
- W2156212005 cites W2055138094 @default.
- W2156212005 cites W2055615904 @default.
- W2156212005 cites W2059438054 @default.
- W2156212005 cites W2061326496 @default.
- W2156212005 cites W2064012369 @default.
- W2156212005 cites W2066669232 @default.
- W2156212005 cites W2068327120 @default.
- W2156212005 cites W2081920788 @default.
- W2156212005 cites W2090806797 @default.
- W2156212005 cites W2092853152 @default.
- W2156212005 cites W2104739065 @default.
- W2156212005 cites W2108147628 @default.
- W2156212005 cites W2109362753 @default.
- W2156212005 cites W2109867267 @default.
- W2156212005 cites W2115864432 @default.
- W2156212005 cites W2119016591 @default.
- W2156212005 cites W2121975620 @default.
- W2156212005 cites W2130329312 @default.
- W2156212005 cites W2132525789 @default.
- W2156212005 cites W2137091788 @default.
- W2156212005 cites W2138694347 @default.
- W2156212005 cites W2138795600 @default.
- W2156212005 cites W2146491739 @default.
- W2156212005 cites W2154692607 @default.
- W2156212005 cites W2162200688 @default.
- W2156212005 cites W2162663200 @default.
- W2156212005 cites W2166462489 @default.
- W2156212005 cites W2171917691 @default.
- W2156212005 cites W2322323797 @default.
- W2156212005 cites W2324558629 @default.
- W2156212005 cites W2434790737 @default.
- W2156212005 cites W4214514832 @default.
- W2156212005 cites W4247917425 @default.
- W2156212005 cites W59708398 @default.
- W2156212005 doi "https://doi.org/10.1001/jamasurg.2014.2257" @default.
- W2156212005 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5015449" @default.
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- W2156212005 hasPublicationYear "2015" @default.
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