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• W2156216715 startingPage "3284" @default.
• W2156216715 abstract "Meiosis is a specialised form of the cell cycle that gives rise to haploid gametes. In Schizosaccharomyces pombe, the products of meiosis are four spores, which are formed by encapsulation of the four meiosis II nuclei within the cytoplasm of the zygote produced by fusion of the mating cells. The S. pombe spindle pole body is remodelled during meiosis II and membrane vesicles are then recruited there to form the forespore membrane, which encapsulates the haploid nucleus to form a prespore. Spore wall material is then deposited, giving rise to the mature spore. The septation initiation network is required to coordinate cytokinesis and mitosis in the vegetative cycle and for spore formation in the meiotic cycle. We have investigated the role of the SIN regulator dma1p in meiosis; we find that although both meiotic divisions occur in the absence of dma1p, asci frequently contain fewer than four spores, which are larger than in wild-type meiosis. Our data indicate that dma1p acts in parallel to the leading-edge proteins and septins to assure proper formation for the forespore membrane. Dma1p also contributes to the temporal regulation of the abundance of the meiosis-specific SIN component mug27p." @default.
• W2156216715 created "2016-06-24" @default.
• W2156216715 creator A5016378396 @default.
• W2156216715 creator A5053893896 @default.
• W2156216715 creator A5066000038 @default.
• W2156216715 date "2010-10-01" @default.
• W2156216715 modified "2023-10-02" @default.
• W2156216715 title "The role of<i>Schizosaccharomyces pombe dma1</i>in spore formation during meiosis" @default.
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• W2156216715 doi "https://doi.org/10.1242/jcs.069112" @default.
• W2156216715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20826461" @default.
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