FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156239670> ?p ?o ?g. }

• W2156239670 endingPage "7" @default.
• W2156239670 startingPage "4784" @default.
• W2156239670 abstract "B lymphocytes in the peripheral circulation are maintained in a non-proliferative state. Antigen recognition stimulates limited proliferation, whereas infection with Epstein-Barr virus (EBV) results in continual proliferation and the outgrowth of immortal cell lines. Because it is not clear at which point in cell cycle the peripheral B lymphocytes are arrested, we characterized the expression of several cell cycle-associated genes in quiescent and stimulated cells. We show that the expression of four cell genes, cdc-2, cyclin E, CD23, and cyclin D2, are up-regulated approximately 100-fold as a result of EBV-mediated immortalization. Because these genes play a positive role in cell proliferation, we suggest that this regulatory switch contributes to controlling entry into the cell cycle. Transient stimulation of quiescent B lymphocytes with either a cocktail of anti-CD40, anti-IgM, and IL4, or EBV results in the rapid expression of the same four genes, suggesting that, after infection, EBV exploits the normal program of B-lymphocyte cell cycle activation." @default.
• W2156239670 created "2016-06-24" @default.
• W2156239670 creator A5003243065 @default.
• W2156239670 creator A5009919677 @default.
• W2156239670 creator A5014682851 @default.
• W2156239670 creator A5016933018 @default.
• W2156239670 creator A5061157286 @default.
• W2156239670 date "1995-11-01" @default.
• W2156239670 modified "2023-10-17" @default.
• W2156239670 title "The normal cell cycle activation program is exploited during the infection of quiescent B lymphocytes by Epstein-Barr virus." @default.
• W2156239670 cites W153423281 @default.
• W2156239670 cites W1615391044 @default.
• W2156239670 cites W1943605355 @default.
• W2156239670 cites W1966797025 @default.
• W2156239670 cites W1974391793 @default.
• W2156239670 cites W1980585800 @default.
• W2156239670 cites W1999330214 @default.
• W2156239670 cites W2000000994 @default.
• W2156239670 cites W2007993419 @default.
• W2156239670 cites W2016168015 @default.
• W2156239670 cites W2018522670 @default.
• W2156239670 cites W2023158512 @default.
• W2156239670 cites W2050432242 @default.
• W2156239670 cites W2082534786 @default.
• W2156239670 cites W2092599452 @default.
• W2156239670 cites W2144935474 @default.
• W2156239670 cites W2150468943 @default.
• W2156239670 cites W2164015588 @default.
• W2156239670 cites W235171311 @default.
• W2156239670 cites W37844384 @default.
• W2156239670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7585505" @default.
• W2156239670 hasPublicationYear "1995" @default.
• W2156239670 type Work @default.
• W2156239670 sameAs 2156239670 @default.
• W2156239670 citedByCount "23" @default.
• W2156239670 countsByYear W21562396702012 @default.
• W2156239670 countsByYear W21562396702013 @default.
• W2156239670 countsByYear W21562396702016 @default.
• W2156239670 countsByYear W21562396702018 @default.
• W2156239670 countsByYear W21562396702020 @default.
• W2156239670 crossrefType "journal-article" @default.
• W2156239670 hasAuthorship W2156239670A5003243065 @default.
• W2156239670 hasAuthorship W2156239670A5009919677 @default.
• W2156239670 hasAuthorship W2156239670A5014682851 @default.
• W2156239670 hasAuthorship W2156239670A5016933018 @default.
• W2156239670 hasAuthorship W2156239670A5061157286 @default.
• W2156239670 hasConcept C120089663 @default.
• W2156239670 hasConcept C141105273 @default.
• W2156239670 hasConcept C1491633281 @default.
• W2156239670 hasConcept C159047783 @default.
• W2156239670 hasConcept C159654299 @default.
• W2156239670 hasConcept C16438837 @default.
• W2156239670 hasConcept C200180986 @default.
• W2156239670 hasConcept C203014093 @default.
• W2156239670 hasConcept C2522874641 @default.
• W2156239670 hasConcept C2776090121 @default.
• W2156239670 hasConcept C2777761686 @default.
• W2156239670 hasConcept C2778453870 @default.
• W2156239670 hasConcept C2780733254 @default.
• W2156239670 hasConcept C2781375147 @default.
• W2156239670 hasConcept C29537977 @default.
• W2156239670 hasConcept C34814297 @default.
• W2156239670 hasConcept C54355233 @default.
• W2156239670 hasConcept C62112901 @default.
• W2156239670 hasConcept C67662055 @default.
• W2156239670 hasConcept C86803240 @default.
• W2156239670 hasConcept C8891405 @default.
• W2156239670 hasConcept C95444343 @default.
• W2156239670 hasConceptScore W2156239670C120089663 @default.
• W2156239670 hasConceptScore W2156239670C141105273 @default.
• W2156239670 hasConceptScore W2156239670C1491633281 @default.
• W2156239670 hasConceptScore W2156239670C159047783 @default.
• W2156239670 hasConceptScore W2156239670C159654299 @default.
• W2156239670 hasConceptScore W2156239670C16438837 @default.
• W2156239670 hasConceptScore W2156239670C200180986 @default.
• W2156239670 hasConceptScore W2156239670C203014093 @default.
• W2156239670 hasConceptScore W2156239670C2522874641 @default.
• W2156239670 hasConceptScore W2156239670C2776090121 @default.
• W2156239670 hasConceptScore W2156239670C2777761686 @default.
• W2156239670 hasConceptScore W2156239670C2778453870 @default.
• W2156239670 hasConceptScore W2156239670C2780733254 @default.
• W2156239670 hasConceptScore W2156239670C2781375147 @default.
• W2156239670 hasConceptScore W2156239670C29537977 @default.
• W2156239670 hasConceptScore W2156239670C34814297 @default.
• W2156239670 hasConceptScore W2156239670C54355233 @default.
• W2156239670 hasConceptScore W2156239670C62112901 @default.
• W2156239670 hasConceptScore W2156239670C67662055 @default.
• W2156239670 hasConceptScore W2156239670C86803240 @default.
• W2156239670 hasConceptScore W2156239670C8891405 @default.
• W2156239670 hasConceptScore W2156239670C95444343 @default.
• W2156239670 hasIssue "21" @default.
• W2156239670 hasLocation W21562396701 @default.
• W2156239670 hasOpenAccess W2156239670 @default.
• W2156239670 hasPrimaryLocation W21562396701 @default.
• W2156239670 hasRelatedWork W1861078759 @default.
• W2156239670 hasRelatedWork W2003438729 @default.
• W2156239670 hasRelatedWork W2047151879 @default.
• W2156239670 hasRelatedWork W2055698166 @default.

• next