Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156249905> ?p ?o ?g. }
- W2156249905 endingPage "29" @default.
- W2156249905 startingPage "29" @default.
- W2156249905 abstract "The clinical significance of sarcopenia and osteoporosis has increased with the increase in the population of older people. Sarcopenia is defined by decreased muscle mass and impaired muscle function, which is related to osteoporosis independently and dependently. Numerous lines of clinical evidence suggest that lean body mass is positively related to bone mass, which leads to reduced fracture risk. Genetic, endocrine and mechanical factors affect both muscle and bone simultaneously. Vitamin D, the growth hormone/insulin-like growth factor I axis and testosterone are physiologically and pathologically important as endocrine factors. These findings suggest the presence of interactions between muscle and bone, which might be very important for understanding the physiology and pathophysiology of sarcopenia and osteoporosis. Muscle/bone relationships include two factors: local control of muscle to bone and systemic humoral interactions between muscle and bone. As a putative local inducer of muscle ossification, we found Tmem119, a parathyroid hormone-responsive osteoblast differentiation factor. Moreover, osteoglycin might be one of the muscle-derived humoral bone anabolic factors. This issue may be important for the development of novel drugs and biomarkers for osteoporosis and sarcopenia. Further research will be necessary to clarify the details of the linkage of muscle and bone." @default.
- W2156249905 created "2016-06-24" @default.
- W2156249905 creator A5010946256 @default.
- W2156249905 date "2014-01-01" @default.
- W2156249905 modified "2023-10-17" @default.
- W2156249905 title "Interaction between Muscle and Bone" @default.
- W2156249905 cites W1664142100 @default.
- W2156249905 cites W1705747559 @default.
- W2156249905 cites W1967271150 @default.
- W2156249905 cites W1968913466 @default.
- W2156249905 cites W1971322232 @default.
- W2156249905 cites W1971598476 @default.
- W2156249905 cites W1974503725 @default.
- W2156249905 cites W1978600482 @default.
- W2156249905 cites W1980434179 @default.
- W2156249905 cites W1980970682 @default.
- W2156249905 cites W1980986010 @default.
- W2156249905 cites W1982261048 @default.
- W2156249905 cites W1982406414 @default.
- W2156249905 cites W1984023554 @default.
- W2156249905 cites W1985325673 @default.
- W2156249905 cites W1988796528 @default.
- W2156249905 cites W1989029721 @default.
- W2156249905 cites W1990852658 @default.
- W2156249905 cites W1993536799 @default.
- W2156249905 cites W2003633907 @default.
- W2156249905 cites W2004724456 @default.
- W2156249905 cites W2004860521 @default.
- W2156249905 cites W2007211529 @default.
- W2156249905 cites W2009307285 @default.
- W2156249905 cites W2009428079 @default.
- W2156249905 cites W2017190356 @default.
- W2156249905 cites W2019451761 @default.
- W2156249905 cites W2025576709 @default.
- W2156249905 cites W2028224225 @default.
- W2156249905 cites W2032050403 @default.
- W2156249905 cites W2032886300 @default.
- W2156249905 cites W2032919896 @default.
- W2156249905 cites W2033889747 @default.
- W2156249905 cites W2042488089 @default.
- W2156249905 cites W2042736567 @default.
- W2156249905 cites W2044638297 @default.
- W2156249905 cites W2045638138 @default.
- W2156249905 cites W2046270293 @default.
- W2156249905 cites W2048661096 @default.
- W2156249905 cites W2049097764 @default.
- W2156249905 cites W2053263660 @default.
- W2156249905 cites W2053984526 @default.
- W2156249905 cites W2055349132 @default.
- W2156249905 cites W2055365717 @default.
- W2156249905 cites W2056821403 @default.
- W2156249905 cites W2063445980 @default.
- W2156249905 cites W2064978553 @default.
- W2156249905 cites W2065089653 @default.
- W2156249905 cites W2068541141 @default.
- W2156249905 cites W2070216811 @default.
- W2156249905 cites W2070519681 @default.
- W2156249905 cites W2071109008 @default.
- W2156249905 cites W2073902275 @default.
- W2156249905 cites W2079362431 @default.
- W2156249905 cites W2080102311 @default.
- W2156249905 cites W2081427992 @default.
- W2156249905 cites W2085397620 @default.
- W2156249905 cites W2092976745 @default.
- W2156249905 cites W2104717998 @default.
- W2156249905 cites W2116967016 @default.
- W2156249905 cites W2118707756 @default.
- W2156249905 cites W2119615557 @default.
- W2156249905 cites W2119818184 @default.
- W2156249905 cites W2123942182 @default.
- W2156249905 cites W2140262648 @default.
- W2156249905 cites W2142685940 @default.
- W2156249905 cites W2149680505 @default.
- W2156249905 cites W2153059487 @default.
- W2156249905 cites W2155409677 @default.
- W2156249905 cites W2166951135 @default.
- W2156249905 cites W2168009241 @default.
- W2156249905 doi "https://doi.org/10.11005/jbm.2014.21.1.29" @default.
- W2156249905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3970293" @default.
- W2156249905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24707465" @default.
- W2156249905 hasPublicationYear "2014" @default.
- W2156249905 type Work @default.
- W2156249905 sameAs 2156249905 @default.
- W2156249905 citedByCount "123" @default.
- W2156249905 countsByYear W21562499052014 @default.
- W2156249905 countsByYear W21562499052015 @default.
- W2156249905 countsByYear W21562499052016 @default.
- W2156249905 countsByYear W21562499052017 @default.
- W2156249905 countsByYear W21562499052018 @default.
- W2156249905 countsByYear W21562499052019 @default.
- W2156249905 countsByYear W21562499052020 @default.
- W2156249905 countsByYear W21562499052021 @default.
- W2156249905 countsByYear W21562499052022 @default.
- W2156249905 countsByYear W21562499052023 @default.
- W2156249905 crossrefType "journal-article" @default.
- W2156249905 hasAuthorship W2156249905A5010946256 @default.
- W2156249905 hasBestOaLocation W21562499051 @default.
- W2156249905 hasConcept C126322002 @default.