FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156374997> ?p ?o ?g. }

• W2156374997 endingPage "729" @default.
• W2156374997 startingPage "721" @default.
• W2156374997 abstract "Complex organ shapes arise from the coordinate actions of individual cells. The Drosophila egg chamber is an organ-like structure that lengthens along its anterior–posterior axis as it grows. This morphogenesis depends on an unusual form of planar polarity in the organ’s outer epithelial layer, the follicle cells. Interestingly, this epithelium also undergoes a directed migration that causes the egg chamber to rotate around its anterior–posterior axis. However, the functional relationship between planar polarity and migration in this tissue is unknown. We have previously reported that mutations in the Misshapen kinase disrupt follicle cell planar polarity. Here we show that Misshapen’s primary role in this system is to promote individual cell motility. Misshapen decreases integrin levels at the basal surface, which may facilitate detachment of each cell’s trailing edge. These data provide mechanistic insight into Misshapen’s conserved role in cell migration and suggest that follicle cell planar polarity may be an emergent property of individual cell migratory behaviors within the epithelium." @default.
• W2156374997 created "2016-06-24" @default.
• W2156374997 creator A5030549665 @default.
• W2156374997 creator A5044259790 @default.
• W2156374997 creator A5084383648 @default.
• W2156374997 date "2013-03-18" @default.
• W2156374997 modified "2023-10-16" @default.
• W2156374997 title "Misshapen decreases integrin levels to promote epithelial motility and planar polarity in Drosophila" @default.
• W2156374997 cites W1964093831 @default.
• W2156374997 cites W1967532512 @default.
• W2156374997 cites W1971106165 @default.
• W2156374997 cites W1974651199 @default.
• W2156374997 cites W1976577398 @default.
• W2156374997 cites W1978157456 @default.
• W2156374997 cites W1984708173 @default.
• W2156374997 cites W1990747492 @default.
• W2156374997 cites W1991906900 @default.
• W2156374997 cites W1993312924 @default.
• W2156374997 cites W2010995441 @default.
• W2156374997 cites W2012553335 @default.
• W2156374997 cites W2021232061 @default.
• W2156374997 cites W2026510213 @default.
• W2156374997 cites W2030274279 @default.
• W2156374997 cites W2036779499 @default.
• W2156374997 cites W2040081015 @default.
• W2156374997 cites W2044110487 @default.
• W2156374997 cites W2051719116 @default.
• W2156374997 cites W2068641012 @default.
• W2156374997 cites W2077431077 @default.
• W2156374997 cites W2090956156 @default.
• W2156374997 cites W2091884095 @default.
• W2156374997 cites W2101659312 @default.
• W2156374997 cites W2103046819 @default.
• W2156374997 cites W2103665862 @default.
• W2156374997 cites W2110995655 @default.
• W2156374997 cites W2112310659 @default.
• W2156374997 cites W2112399803 @default.
• W2156374997 cites W2115758207 @default.
• W2156374997 cites W2116691044 @default.
• W2156374997 cites W2122132730 @default.
• W2156374997 cites W2126391346 @default.
• W2156374997 cites W2127481925 @default.
• W2156374997 cites W2129133276 @default.
• W2156374997 cites W2133471368 @default.
• W2156374997 cites W2135553987 @default.
• W2156374997 cites W2138747143 @default.
• W2156374997 cites W2139463164 @default.
• W2156374997 cites W2147026515 @default.
• W2156374997 cites W2152773922 @default.
• W2156374997 cites W2154142433 @default.
• W2156374997 cites W2276527648 @default.
• W2156374997 cites W45421301 @default.
• W2156374997 cites W2044420344 @default.
• W2156374997 doi "https://doi.org/10.1083/jcb.201209129" @default.
• W2156374997 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3601364" @default.
• W2156374997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23509067" @default.
• W2156374997 hasPublicationYear "2013" @default.
• W2156374997 type Work @default.
• W2156374997 sameAs 2156374997 @default.
• W2156374997 citedByCount "62" @default.
• W2156374997 countsByYear W21563749972013 @default.
• W2156374997 countsByYear W21563749972014 @default.
• W2156374997 countsByYear W21563749972015 @default.
• W2156374997 countsByYear W21563749972016 @default.
• W2156374997 countsByYear W21563749972017 @default.
• W2156374997 countsByYear W21563749972018 @default.
• W2156374997 countsByYear W21563749972019 @default.
• W2156374997 countsByYear W21563749972020 @default.
• W2156374997 countsByYear W21563749972021 @default.
• W2156374997 countsByYear W21563749972022 @default.
• W2156374997 countsByYear W21563749972023 @default.
• W2156374997 crossrefType "journal-article" @default.
• W2156374997 hasAuthorship W2156374997A5030549665 @default.
• W2156374997 hasAuthorship W2156374997A5044259790 @default.
• W2156374997 hasAuthorship W2156374997A5084383648 @default.
• W2156374997 hasBestOaLocation W21563749971 @default.
• W2156374997 hasConcept C104317684 @default.
• W2156374997 hasConcept C105702510 @default.
• W2156374997 hasConcept C137738243 @default.
• W2156374997 hasConcept C1491633281 @default.
• W2156374997 hasConcept C195687474 @default.
• W2156374997 hasConcept C2777361361 @default.
• W2156374997 hasConcept C39587587 @default.
• W2156374997 hasConcept C40692019 @default.
• W2156374997 hasConcept C49353375 @default.
• W2156374997 hasConcept C529295009 @default.
• W2156374997 hasConcept C54355233 @default.
• W2156374997 hasConcept C58207958 @default.
• W2156374997 hasConcept C86803240 @default.
• W2156374997 hasConcept C95444343 @default.
• W2156374997 hasConceptScore W2156374997C104317684 @default.
• W2156374997 hasConceptScore W2156374997C105702510 @default.
• W2156374997 hasConceptScore W2156374997C137738243 @default.
• W2156374997 hasConceptScore W2156374997C1491633281 @default.
• W2156374997 hasConceptScore W2156374997C195687474 @default.
• W2156374997 hasConceptScore W2156374997C2777361361 @default.
• W2156374997 hasConceptScore W2156374997C39587587 @default.
• W2156374997 hasConceptScore W2156374997C40692019 @default.

• next