FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156435192> ?p ?o ?g. }

• W2156435192 endingPage "2760" @default.
• W2156435192 startingPage "2752" @default.
• W2156435192 abstract "ABSTRACT This study describes the characterization of the riboflavin transport protein RibU in the lactic acid bacterium Lactococcus lactis subsp. cremoris NZ9000. RibU is predicted to contain five membrane-spanning segments and is a member of a novel transport protein family, not described in the Transport Classification Database. Transcriptional analysis revealed that ribU transcription is downregulated in response to riboflavin and flavin mononucleotide (FMN), presumably by means of the structurally conserved RFN (riboflavin) element located between the transcription start site and the start codon. An L. lactis strain carrying a mutated ribU gene exhibits altered transcriptional control of the riboflavin biosynthesis operon ribGBAH in response to riboflavin and FMN and does not consume riboflavin from its growth medium. Furthermore, it was shown that radiolabeled riboflavin is not taken up by the ribU mutant strain, in contrast to the wild-type strain, directly demonstrating the involvement of RibU in riboflavin uptake. FMN and the toxic riboflavin analogue roseoflavin were shown to inhibit riboflavin uptake and are likely to be RibU substrates. FMN transport by RibU is consistent with the observed transcriptional regulation of the ribGBAH operon by external FMN. The presented transport data are consistent with a uniport mechanism for riboflavin translocation and provide the first detailed molecular and functional analysis of a bacterial protein involved in riboflavin transport." @default.
• W2156435192 created "2016-06-24" @default.
• W2156435192 creator A5019871566 @default.
• W2156435192 creator A5041070000 @default.
• W2156435192 creator A5065079907 @default.
• W2156435192 creator A5065140511 @default.
• W2156435192 creator A5075802016 @default.
• W2156435192 creator A5080383708 @default.
• W2156435192 date "2006-04-15" @default.
• W2156435192 modified "2023-09-25" @default.
• W2156435192 title "The Riboflavin Transporter RibU in <i>Lactococcus lactis</i> : Molecular Characterization of Gene Expression and the Transport Mechanism" @default.
• W2156435192 cites W1569389037 @default.
• W2156435192 cites W1594974221 @default.
• W2156435192 cites W1940868647 @default.
• W2156435192 cites W1942690669 @default.
• W2156435192 cites W1957635815 @default.
• W2156435192 cites W1963989657 @default.
• W2156435192 cites W1975179907 @default.
• W2156435192 cites W1987641460 @default.
• W2156435192 cites W1991634127 @default.
• W2156435192 cites W2003898032 @default.
• W2156435192 cites W2007954929 @default.
• W2156435192 cites W2030621944 @default.
• W2156435192 cites W2031512086 @default.
• W2156435192 cites W2048128153 @default.
• W2156435192 cites W2074650885 @default.
• W2156435192 cites W2085877774 @default.
• W2156435192 cites W2085890527 @default.
• W2156435192 cites W2103032054 @default.
• W2156435192 cites W2115840790 @default.
• W2156435192 cites W2123416485 @default.
• W2156435192 cites W2123509606 @default.
• W2156435192 cites W2124616640 @default.
• W2156435192 cites W2126958225 @default.
• W2156435192 cites W2130558307 @default.
• W2156435192 cites W2137175189 @default.
• W2156435192 cites W2139325759 @default.
• W2156435192 cites W2140794624 @default.
• W2156435192 cites W2141157874 @default.
• W2156435192 cites W2145267759 @default.
• W2156435192 cites W2152770371 @default.
• W2156435192 cites W2158381555 @default.
• W2156435192 cites W2158714788 @default.
• W2156435192 cites W2166756758 @default.
• W2156435192 cites W2167142171 @default.
• W2156435192 cites W2181469541 @default.
• W2156435192 cites W3024531541 @default.
• W2156435192 doi "https://doi.org/10.1128/jb.188.8.2752-2760.2006" @default.
• W2156435192 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1446998" @default.
• W2156435192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16585736" @default.
• W2156435192 hasPublicationYear "2006" @default.
• W2156435192 type Work @default.
• W2156435192 sameAs 2156435192 @default.
• W2156435192 citedByCount "75" @default.
• W2156435192 countsByYear W21564351922012 @default.
• W2156435192 countsByYear W21564351922013 @default.
• W2156435192 countsByYear W21564351922014 @default.
• W2156435192 countsByYear W21564351922015 @default.
• W2156435192 countsByYear W21564351922016 @default.
• W2156435192 countsByYear W21564351922017 @default.
• W2156435192 countsByYear W21564351922018 @default.
• W2156435192 countsByYear W21564351922019 @default.
• W2156435192 countsByYear W21564351922020 @default.
• W2156435192 countsByYear W21564351922021 @default.
• W2156435192 countsByYear W21564351922023 @default.
• W2156435192 crossrefType "journal-article" @default.
• W2156435192 hasAuthorship W2156435192A5019871566 @default.
• W2156435192 hasAuthorship W2156435192A5041070000 @default.
• W2156435192 hasAuthorship W2156435192A5065079907 @default.
• W2156435192 hasAuthorship W2156435192A5065140511 @default.
• W2156435192 hasAuthorship W2156435192A5075802016 @default.
• W2156435192 hasAuthorship W2156435192A5080383708 @default.
• W2156435192 hasBestOaLocation W21564351921 @default.
• W2156435192 hasConcept C104317684 @default.
• W2156435192 hasConcept C115335371 @default.
• W2156435192 hasConcept C143065580 @default.
• W2156435192 hasConcept C149011108 @default.
• W2156435192 hasConcept C181199279 @default.
• W2156435192 hasConcept C203075996 @default.
• W2156435192 hasConcept C2775920511 @default.
• W2156435192 hasConcept C2776155809 @default.
• W2156435192 hasConcept C2777427158 @default.
• W2156435192 hasConcept C2780011460 @default.
• W2156435192 hasConcept C33093398 @default.
• W2156435192 hasConcept C523546767 @default.
• W2156435192 hasConcept C54355233 @default.
• W2156435192 hasConcept C55493867 @default.
• W2156435192 hasConcept C71995715 @default.
• W2156435192 hasConcept C86803240 @default.
• W2156435192 hasConceptScore W2156435192C104317684 @default.
• W2156435192 hasConceptScore W2156435192C115335371 @default.
• W2156435192 hasConceptScore W2156435192C143065580 @default.
• W2156435192 hasConceptScore W2156435192C149011108 @default.
• W2156435192 hasConceptScore W2156435192C181199279 @default.
• W2156435192 hasConceptScore W2156435192C203075996 @default.
• W2156435192 hasConceptScore W2156435192C2775920511 @default.
• W2156435192 hasConceptScore W2156435192C2776155809 @default.
• W2156435192 hasConceptScore W2156435192C2777427158 @default.

• next