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- W2156553635 abstract "The intravenous injection of certain drugs, such as psychomotor stimulants, can function as a reinforcer to engender and maintain behavior in rats and monkeys. Such behavior has served as a laboratory counterpart to human drug-seeking and drug-taking behavior. However, the levels of behavior maintained by drug injections in experimental animals are usually lower than would be expected from observations of the extended sequences of behavior involved in the procurement, preparation, and administration of a drug by humans. The low levels of behavior may arise from the common practice of studying experimental animals under conditions in which every response or every few responses results in a drug injection during long experimental sessions lasting 3 to 24 hours. Under these conditions, mean response rates have been less than 0.1 response per second; and response rates decrease further as the dose per injection is increased above some level (e.g., Pickens and Thompson, 1968; Goldberg, Hoffmeister, Schlichting and Wuttke, 1971; Wilson, Hitomi and Schuster, 1971)." @default.
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- W2156553635 date "1977-01-01" @default.
- W2156553635 modified "2023-09-29" @default.
- W2156553635 title "Reinforcement of Behavior by Cocaine Injections" @default.
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- W2156553635 doi "https://doi.org/10.1007/978-1-4684-3087-5_25" @default.
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