FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156753843> ?p ?o ?g. }

• W2156753843 endingPage "87" @default.
• W2156753843 startingPage "77" @default.
• W2156753843 abstract "Several antimicrobials act by inhibiting the synthesis of nucleic acids (rifamycins, sulfamides, diaminopyridines), modifying their conformation (quinolones, coumarins) or causing irreversible lesions (nitroimidazoles, nitrofurans). The resistance mechanisms are: a reduction in intracytoplasmic accumulation, modification of the target or the production of a new low-affinity target and, more rarely, enzyme inactivation. Although the mechanisms affecting the targets are specific to each family and can lead to high-level resistance, the reduced permeability of the membrane and the increased efflux are non-specific and result in low-level cross-resistance between several families. The genetic mediation is usually chromosomal for rifamycins and quinolones, although plasmid-mediated resistant genes have been observed. On the other hand, for sulfamides and trimethoprim, plasmid-borne genes are frequent. Resistance to nitroimidazoles and nitrofurans is still not widely understood." @default.
• W2156753843 created "2016-06-24" @default.
• W2156753843 creator A5020574513 @default.
• W2156753843 creator A5063446203 @default.
• W2156753843 date "2012-04-01" @default.
• W2156753843 modified "2023-09-30" @default.
• W2156753843 title "Antimicrobials that affect the synthesis and conformation of nucleic acids" @default.
• W2156753843 cites W1547728614 @default.
• W2156753843 cites W1655541135 @default.
• W2156753843 cites W1964931511 @default.
• W2156753843 cites W1974898319 @default.
• W2156753843 cites W1979295331 @default.
• W2156753843 cites W1991364432 @default.
• W2156753843 cites W1999642059 @default.
• W2156753843 cites W2003862523 @default.
• W2156753843 cites W2009089119 @default.
• W2156753843 cites W2020252151 @default.
• W2156753843 cites W2022234554 @default.
• W2156753843 cites W2031956393 @default.
• W2156753843 cites W2038211892 @default.
• W2156753843 cites W2069340075 @default.
• W2156753843 cites W2072024834 @default.
• W2156753843 cites W2096099500 @default.
• W2156753843 cites W2096898012 @default.
• W2156753843 cites W2097946615 @default.
• W2156753843 cites W2108709192 @default.
• W2156753843 cites W2109751189 @default.
• W2156753843 cites W2119764159 @default.
• W2156753843 cites W2120061656 @default.
• W2156753843 cites W2122112671 @default.
• W2156753843 cites W2137519474 @default.
• W2156753843 cites W2138504093 @default.
• W2156753843 cites W2138583425 @default.
• W2156753843 cites W2141564279 @default.
• W2156753843 cites W2144706728 @default.
• W2156753843 cites W2149410208 @default.
• W2156753843 cites W2154226051 @default.
• W2156753843 cites W2154858303 @default.
• W2156753843 cites W2170555633 @default.
• W2156753843 doi "https://doi.org/10.20506/rst.31.1.2102" @default.
• W2156753843 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22849269" @default.
• W2156753843 hasPublicationYear "2012" @default.
• W2156753843 type Work @default.
• W2156753843 sameAs 2156753843 @default.
• W2156753843 citedByCount "7" @default.
• W2156753843 countsByYear W21567538432012 @default.
• W2156753843 countsByYear W21567538432013 @default.
• W2156753843 countsByYear W21567538432015 @default.
• W2156753843 countsByYear W21567538432016 @default.
• W2156753843 countsByYear W21567538432021 @default.
• W2156753843 countsByYear W21567538432023 @default.
• W2156753843 crossrefType "journal-article" @default.
• W2156753843 hasAuthorship W2156753843A5020574513 @default.
• W2156753843 hasAuthorship W2156753843A5063446203 @default.
• W2156753843 hasConcept C104317684 @default.
• W2156753843 hasConcept C178790620 @default.
• W2156753843 hasConcept C185592680 @default.
• W2156753843 hasConcept C200082930 @default.
• W2156753843 hasConcept C22744801 @default.
• W2156753843 hasConcept C24107716 @default.
• W2156753843 hasConcept C2776955177 @default.
• W2156753843 hasConcept C2992270614 @default.
• W2156753843 hasConcept C41625074 @default.
• W2156753843 hasConcept C4937899 @default.
• W2156753843 hasConcept C54355233 @default.
• W2156753843 hasConcept C55493867 @default.
• W2156753843 hasConcept C86803240 @default.
• W2156753843 hasConceptScore W2156753843C104317684 @default.
• W2156753843 hasConceptScore W2156753843C178790620 @default.
• W2156753843 hasConceptScore W2156753843C185592680 @default.
• W2156753843 hasConceptScore W2156753843C200082930 @default.
• W2156753843 hasConceptScore W2156753843C22744801 @default.
• W2156753843 hasConceptScore W2156753843C24107716 @default.
• W2156753843 hasConceptScore W2156753843C2776955177 @default.
• W2156753843 hasConceptScore W2156753843C2992270614 @default.
• W2156753843 hasConceptScore W2156753843C41625074 @default.
• W2156753843 hasConceptScore W2156753843C4937899 @default.
• W2156753843 hasConceptScore W2156753843C54355233 @default.
• W2156753843 hasConceptScore W2156753843C55493867 @default.
• W2156753843 hasConceptScore W2156753843C86803240 @default.
• W2156753843 hasIssue "1" @default.
• W2156753843 hasLocation W21567538431 @default.
• W2156753843 hasLocation W21567538432 @default.
• W2156753843 hasOpenAccess W2156753843 @default.
• W2156753843 hasPrimaryLocation W21567538431 @default.
• W2156753843 hasRelatedWork W2002885566 @default.
• W2156753843 hasRelatedWork W2095212420 @default.
• W2156753843 hasRelatedWork W2122039852 @default.
• W2156753843 hasRelatedWork W2126853397 @default.
• W2156753843 hasRelatedWork W2136871577 @default.
• W2156753843 hasRelatedWork W2148571818 @default.
• W2156753843 hasRelatedWork W2151265853 @default.
• W2156753843 hasRelatedWork W2187711834 @default.
• W2156753843 hasRelatedWork W2396822601 @default.
• W2156753843 hasRelatedWork W3193369686 @default.
• W2156753843 hasVolume "31" @default.
• W2156753843 isParatext "false" @default.
• W2156753843 isRetracted "false" @default.

• next