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• W2156775585 abstract "The aim of this study was to investigate the antinociceptive and anti-inflammatory activities of the essential oil of Satureja thymbra. L. (Lamiaceae). Antinociceptive activity of the essential oil was measured by the formalin test in mice and by the light tail-flick and hot-plate methods in rats. The paw-edema test was performed in rats to evaluate the anti-inflammatory effect of the essential oil. Motor coordination was assessed with a rotarod apparatus. Although the essential oil produced an antinociceptive effect during both the early (50 and 100 mg kg−1) and late phases (25, 50, and 100 mg kg−1) of the formalin test, it did not exert any significant antinociceptive and anti-inflammatory effects in tail-flick and paw-edema tests, respectively. In addition, a significant antinociceptive effect was detected in the hot-plate test (100 and 200 mg kg−1). No significant change was detected in sensory motor performance. In conclusion, S. thymbra. L. essential oil does not exert any anti-inflammatory effect while it may have central analgesic activity in mice and rats." @default.
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• W2156775585 date "2006-01-01" @default.
• W2156775585 modified "2023-09-26" @default.
• W2156775585 title "Evaluation of the Antinociceptive and Anti-inflammatory Activities of<i>Satureja thymbra</i>. L. Essential Oil" @default.
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• W2156775585 doi "https://doi.org/10.1080/13880200600896827" @default.
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