FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156775590> ?p ?o ?g. }

• W2156775590 endingPage "13" @default.
• W2156775590 startingPage "1" @default.
• W2156775590 abstract "Patients with cystic fibrosis (CF) have a high prevalence of Pseudomonas aeruginosa infection which causes chronic infection of the mucosal surfaces of the lung. This results in recurrent immune stimulation and hypergammaglobulinemia. The present study examines the levels of circulating Ig classes, IgG and IgA subclasses in 13 adult patients with CF during acute pulmonary infection and post-exacerbation. Total serum IgG levels were raised in the patients during infection and post-treatment when compared to the normal range (mean +/- SEM: 17.21 +/- 1.4 g/l vs 16.45 +/- 1.5 g/l respectively; normal range 8-16 g/l). In contrast, total IgM (2.6 +/- 0.26 vs 2.69 +/- 2.74 g/l; normal range 0.6-2.8 g/l) and IgA levels (2.5 +/- 0.52 vs 2.41 +/- 0.48 g/l; normal range 0.5-4 g/l) remained unchanged when examined during all stages of the disease. Of the 13 patients studied, 69%, 39% and 31% had IgG, IgM and IgA levels respectively raised above the normal range values. The mean levels of individual IgG subclasses examined in this group of patients revealed values within the normal ranges, however IgG2 and IgG3 were increased in 31% and 46% of patients. Individual IgG3 levels fell in 77% (10/13) and IgG4 in 62% (8/13) of the patients post-exacerbation. With regard to IgA subclasses, significant reduction in the IgA1 levels were observed post treatment (3687 +/- 539 mg/l vs 2713 +/- 498 mg/l, p < 0.01). In contrast, IgA2 levels were increased from 279 +/- 49 mg/l to 421 +/- 69 mg/l, although statistical significance was not reached. Upon antibiotic treatment for infection, the findings in this study show that IgA1 which is susceptible to bacterial proteases is reduced with a concommitant increase in the protease resistant IgA2 subclass. Moreover, patients colonised with non-mucoid strains of P. aeroginosa had higher total IgA levels due to the raised IgA1 subclass whereas they had lower IgG levels due to low IgG2 and IgG4 subclasses." @default.
• W2156775590 created "2016-06-24" @default.
• W2156775590 creator A5000515741 @default.
• W2156775590 creator A5005244252 @default.
• W2156775590 creator A5019245159 @default.
• W2156775590 creator A5020142193 @default.
• W2156775590 creator A5022630337 @default.
• W2156775590 creator A5057112125 @default.
• W2156775590 date "1994-01-01" @default.
• W2156775590 modified "2023-10-13" @default.
• W2156775590 title "Serum IgA and IGg Subclasses During Treatment for Acute Respiratory Exacerbation in Cystic Fibrosis: Analysis of Patients Colonised with Mucoid or Non-Mucoid Strains of Pseudomonas Aeruginosa" @default.
• W2156775590 cites W112951069 @default.
• W2156775590 cites W1567930760 @default.
• W2156775590 cites W1573262030 @default.
• W2156775590 cites W1886054339 @default.
• W2156775590 cites W1886746997 @default.
• W2156775590 cites W1958307240 @default.
• W2156775590 cites W1976287695 @default.
• W2156775590 cites W1991850017 @default.
• W2156775590 cites W2002983094 @default.
• W2156775590 cites W2013938272 @default.
• W2156775590 cites W2021944596 @default.
• W2156775590 cites W2041507812 @default.
• W2156775590 cites W2046354137 @default.
• W2156775590 cites W2060627925 @default.
• W2156775590 cites W2083966368 @default.
• W2156775590 cites W2099885683 @default.
• W2156775590 cites W2103226260 @default.
• W2156775590 cites W2113230460 @default.
• W2156775590 cites W2131830407 @default.
• W2156775590 cites W2162072688 @default.
• W2156775590 cites W2162584679 @default.
• W2156775590 cites W2167264388 @default.
• W2156775590 cites W2171149861 @default.
• W2156775590 cites W2171638287 @default.
• W2156775590 cites W2201352999 @default.
• W2156775590 cites W2319623709 @default.
• W2156775590 cites W2320919448 @default.
• W2156775590 doi "https://doi.org/10.3109/08820139409063428" @default.
• W2156775590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8144195" @default.
• W2156775590 hasPublicationYear "1994" @default.
• W2156775590 type Work @default.
• W2156775590 sameAs 2156775590 @default.
• W2156775590 citedByCount "10" @default.
• W2156775590 countsByYear W21567755902013 @default.
• W2156775590 countsByYear W21567755902020 @default.
• W2156775590 countsByYear W21567755902021 @default.
• W2156775590 countsByYear W21567755902022 @default.
• W2156775590 crossrefType "journal-article" @default.
• W2156775590 hasAuthorship W2156775590A5000515741 @default.
• W2156775590 hasAuthorship W2156775590A5005244252 @default.
• W2156775590 hasAuthorship W2156775590A5019245159 @default.
• W2156775590 hasAuthorship W2156775590A5020142193 @default.
• W2156775590 hasAuthorship W2156775590A5022630337 @default.
• W2156775590 hasAuthorship W2156775590A5057112125 @default.
• W2156775590 hasConcept C126322002 @default.
• W2156775590 hasConcept C159654299 @default.
• W2156775590 hasConcept C203014093 @default.
• W2156775590 hasConcept C2776178081 @default.
• W2156775590 hasConcept C2776938444 @default.
• W2156775590 hasConcept C2777014857 @default.
• W2156775590 hasConcept C2777637488 @default.
• W2156775590 hasConcept C2777714996 @default.
• W2156775590 hasConcept C2779102806 @default.
• W2156775590 hasConcept C2779379686 @default.
• W2156775590 hasConcept C2780514984 @default.
• W2156775590 hasConcept C2780898057 @default.
• W2156775590 hasConcept C523546767 @default.
• W2156775590 hasConcept C534529494 @default.
• W2156775590 hasConcept C54355233 @default.
• W2156775590 hasConcept C71924100 @default.
• W2156775590 hasConcept C86803240 @default.
• W2156775590 hasConcept C8891405 @default.
• W2156775590 hasConcept C90924648 @default.
• W2156775590 hasConceptScore W2156775590C126322002 @default.
• W2156775590 hasConceptScore W2156775590C159654299 @default.
• W2156775590 hasConceptScore W2156775590C203014093 @default.
• W2156775590 hasConceptScore W2156775590C2776178081 @default.
• W2156775590 hasConceptScore W2156775590C2776938444 @default.
• W2156775590 hasConceptScore W2156775590C2777014857 @default.
• W2156775590 hasConceptScore W2156775590C2777637488 @default.
• W2156775590 hasConceptScore W2156775590C2777714996 @default.
• W2156775590 hasConceptScore W2156775590C2779102806 @default.
• W2156775590 hasConceptScore W2156775590C2779379686 @default.
• W2156775590 hasConceptScore W2156775590C2780514984 @default.
• W2156775590 hasConceptScore W2156775590C2780898057 @default.
• W2156775590 hasConceptScore W2156775590C523546767 @default.
• W2156775590 hasConceptScore W2156775590C534529494 @default.
• W2156775590 hasConceptScore W2156775590C54355233 @default.
• W2156775590 hasConceptScore W2156775590C71924100 @default.
• W2156775590 hasConceptScore W2156775590C86803240 @default.
• W2156775590 hasConceptScore W2156775590C8891405 @default.
• W2156775590 hasConceptScore W2156775590C90924648 @default.
• W2156775590 hasIssue "1" @default.
• W2156775590 hasLocation W21567755901 @default.
• W2156775590 hasLocation W21567755902 @default.
• W2156775590 hasOpenAccess W2156775590 @default.
• W2156775590 hasPrimaryLocation W21567755901 @default.

• next