FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156814900> ?p ?o ?g. }

• W2156814900 endingPage "558" @default.
• W2156814900 startingPage "552" @default.
• W2156814900 abstract "Interleukin (IL)-18 is a cardiotropic proinflammatory cytokine chronically elevated in the serum of patients with cardiac hypertrophy (LVH). The purpose of this study was to examine the role of IL-18 in pressure-overload hypertrophy using wild type (WT) and IL-18 -/- (null) mice. Adult male C57Bl/6 mice underwent transaortic constriction (TAC) for 7days or sham surgery. Heart weight/body weight ratios showed blunted hypertrophy in IL-18 null TAC mice compared to WT TAC animals. Microarray analyses indicated differential expression of hypertrophy-related genes in WT versus IL-18 nulls. Northern, Western, and EMSA analyses showed Akt and GATA4 were increased in WT but unchanged in IL-18 null mice. Our results demonstrate blunted hypertrophy with reduced expression of contractile-, hypertrophy-, and remodeling-associated genes following pressure overload in IL-18 null mice, and suggest that IL-18 plays a critical role in the hypertrophic response." @default.
• W2156814900 created "2016-06-24" @default.
• W2156814900 creator A5011820584 @default.
• W2156814900 creator A5030206027 @default.
• W2156814900 creator A5052469404 @default.
• W2156814900 creator A5052503903 @default.
• W2156814900 creator A5053647027 @default.
• W2156814900 creator A5062659962 @default.
• W2156814900 creator A5076915690 @default.
• W2156814900 creator A5086367782 @default.
• W2156814900 creator A5088367070 @default.
• W2156814900 date "2007-03-01" @default.
• W2156814900 modified "2023-09-27" @default.
• W2156814900 title "Interleukin-18 knockout mice display maladaptive cardiac hypertrophy in response to pressure overload" @default.
• W2156814900 cites W1885912605 @default.
• W2156814900 cites W1900281246 @default.
• W2156814900 cites W1971684362 @default.
• W2156814900 cites W1979363352 @default.
• W2156814900 cites W1987690650 @default.
• W2156814900 cites W1989358807 @default.
• W2156814900 cites W1989457690 @default.
• W2156814900 cites W1991611246 @default.
• W2156814900 cites W1994419384 @default.
• W2156814900 cites W1997502686 @default.
• W2156814900 cites W2005456367 @default.
• W2156814900 cites W2022452100 @default.
• W2156814900 cites W2026161448 @default.
• W2156814900 cites W2038009264 @default.
• W2156814900 cites W2051867686 @default.
• W2156814900 cites W2061665489 @default.
• W2156814900 cites W2111340301 @default.
• W2156814900 cites W2127154429 @default.
• W2156814900 cites W2127154601 @default.
• W2156814900 cites W2130021283 @default.
• W2156814900 cites W2131989143 @default.
• W2156814900 cites W2136094484 @default.
• W2156814900 cites W2138130022 @default.
• W2156814900 cites W2145094705 @default.
• W2156814900 cites W2148911704 @default.
• W2156814900 cites W2154201149 @default.
• W2156814900 cites W2155027729 @default.
• W2156814900 cites W2162210935 @default.
• W2156814900 cites W2166037275 @default.
• W2156814900 cites W2169367420 @default.
• W2156814900 cites W2171706231 @default.
• W2156814900 cites W2171908036 @default.
• W2156814900 cites W76085819 @default.
• W2156814900 doi "https://doi.org/10.1016/j.bbrc.2007.01.030" @default.
• W2156814900 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1847636" @default.
• W2156814900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17250807" @default.
• W2156814900 hasPublicationYear "2007" @default.
• W2156814900 type Work @default.
• W2156814900 sameAs 2156814900 @default.
• W2156814900 citedByCount "44" @default.
• W2156814900 countsByYear W21568149002012 @default.
• W2156814900 countsByYear W21568149002013 @default.
• W2156814900 countsByYear W21568149002014 @default.
• W2156814900 countsByYear W21568149002015 @default.
• W2156814900 countsByYear W21568149002016 @default.
• W2156814900 countsByYear W21568149002017 @default.
• W2156814900 countsByYear W21568149002018 @default.
• W2156814900 countsByYear W21568149002019 @default.
• W2156814900 countsByYear W21568149002020 @default.
• W2156814900 countsByYear W21568149002021 @default.
• W2156814900 countsByYear W21568149002022 @default.
• W2156814900 crossrefType "journal-article" @default.
• W2156814900 hasAuthorship W2156814900A5011820584 @default.
• W2156814900 hasAuthorship W2156814900A5030206027 @default.
• W2156814900 hasAuthorship W2156814900A5052469404 @default.
• W2156814900 hasAuthorship W2156814900A5052503903 @default.
• W2156814900 hasAuthorship W2156814900A5053647027 @default.
• W2156814900 hasAuthorship W2156814900A5062659962 @default.
• W2156814900 hasAuthorship W2156814900A5076915690 @default.
• W2156814900 hasAuthorship W2156814900A5086367782 @default.
• W2156814900 hasAuthorship W2156814900A5088367070 @default.
• W2156814900 hasBestOaLocation W21568149002 @default.
• W2156814900 hasConcept C104317684 @default.
• W2156814900 hasConcept C126322002 @default.
• W2156814900 hasConcept C127561419 @default.
• W2156814900 hasConcept C134018914 @default.
• W2156814900 hasConcept C142724271 @default.
• W2156814900 hasConcept C164027704 @default.
• W2156814900 hasConcept C167414201 @default.
• W2156814900 hasConcept C170493617 @default.
• W2156814900 hasConcept C182704531 @default.
• W2156814900 hasConcept C204787440 @default.
• W2156814900 hasConcept C2775961468 @default.
• W2156814900 hasConcept C2776914184 @default.
• W2156814900 hasConcept C2778271984 @default.
• W2156814900 hasConcept C2778690821 @default.
• W2156814900 hasConcept C3018791406 @default.
• W2156814900 hasConcept C55493867 @default.
• W2156814900 hasConcept C62478195 @default.
• W2156814900 hasConcept C68239362 @default.
• W2156814900 hasConcept C71924100 @default.
• W2156814900 hasConcept C75217442 @default.
• W2156814900 hasConcept C86803240 @default.
• W2156814900 hasConcept C95444343 @default.

• next