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• W2156818391 abstract "A novel class of biofunctional silole nanocrystals with the potential to create highly sensitive immunoassay was firstly demonstrated. Biolabels were constructed by encapsulating nanocrystalline hexaphenylsilole [Ph2Si(CPh)4; HPS] within ultrathin polyelectrolyte layers via the layer-by-layer (LbL) technique that provided an “interface” for the attachment of antibodies. A high ratio of fluorescent dyes to biomolecules (F/P ratio; 2.4×103) was achieved without self-quenching problem. The aggregation-induced emission (AIE) feature offered silole biolabels the sensitivity 40- to 140-fold higher than that of a start-of-the-art immunoassay using directly fluorescent-labeled antibodies." @default.
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• W2156818391 date "2004-12-01" @default.
• W2156818391 modified "2023-10-16" @default.
• W2156818391 title "Silole nanocrystals as novel biolabels" @default.
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• W2156818391 doi "https://doi.org/10.1016/j.jim.2004.09.016" @default.
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