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- W2156829919 endingPage "948" @default.
- W2156829919 startingPage "937" @default.
- W2156829919 abstract "Primary burning mouth syndrome (BMS) is a chronic oral condition characterized by burning pain often accompanied with taste dysfunction and xerostomia. The most compelling evidence concerning BMS pathophysiology comes from studies on the somatosensory system using neurophysiologic or psychophysical methods such as blink reflex, thermal quantitative sensory testing, as well as functional brain imaging. They have provided convincing evidence for neuropathic involvement at several levels of the somatosensory system in BMS pain pathophysiology. The number of taste function studies trying to substantiate the subjective taste disturbances or studies on salivary factors in BMS is much more limited, and most of them suffer from definitional and methodological problems. This review aims to critically evaluate the existing literature on the pathophysiology of BMS, paying special attention to the correctness of case selection and the methodology used in published studies, and to summarize the current state of knowledge. Based on the recognition of several gaps in the current understanding of the pathophysiology of BMS especially as regards taste and pain system interactions, the review ends with future scenarios for research in this area." @default.
- W2156829919 created "2016-06-24" @default.
- W2156829919 creator A5003884842 @default.
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- W2156829919 creator A5079320079 @default.
- W2156829919 creator A5087782866 @default.
- W2156829919 creator A5091315336 @default.
- W2156829919 date "2015-06-25" @default.
- W2156829919 modified "2023-10-02" @default.
- W2156829919 title "Pathophysiology of primary burning mouth syndrome with special focus on taste dysfunction: a review" @default.
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