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- W2156870562 abstract "Summary Introduction. Insulinoma belongs to the most functional pancreatic neuroendocrine neoplasms, with specific problems in their diagnosis, localization and treatment. Aim. The aim of our study was to describe diagnostic problems, clinicians cope to correctly determine insulinoma. Material and methods. We included 74 patients (52 females and 22 males) admitted to the Department of Endocrinology and Diabetology, Collegium Medicum in Bydgoszcz, University of Nicolaus Copernicus in Torun between 2001 and 2010, because of clinical suspicion of insulinoma: weakness, sweating, blured vision, confusion and dizziness. They all were sub- jected to a 72-hour-fasting test, which is considered as the gold standard to recognize insulinoma. Results. In our study the Whipple's triad (neurologic symptoms of hypoglycemia, blood glucose levels less than 40 mg/dl and immediate alleviation of symptoms after glucose ingestion) was present only in 10 of 74 patients (8 females and 2 males). We implemented ultrasonography, computed tomography, somatostatin receptor scintigraphy and endoscopic ultrasonogra- phy. Only in one of the patients with diagnosed insulinoma a single tumor (2 cm), situated on a border of head and corpus of pancreas, was localized with the use of the computed tomography. Also in two of the patients with the use of the endoscopic ultrasonography an insulinoma was recognized. Conclusions. Treatment strategy of insulinoma is surgical removal of the tumor. A simple enucleation of the tumor is suc- cessful in over 90% of cases. The diagnosis of insulinoma is very difficult, despite available investigative methods." @default.
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- W2156870562 date "2013-10-16" @default.
- W2156870562 modified "2023-10-02" @default.
- W2156870562 title "Neuroendocrine tumors - insulinoma in clinical practise" @default.
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