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- W2156874308 abstract "Significance The release of actinides in the environment, particularly after a nuclear power plant accident or the potential use of a radiological dispersal device, is a public health threat, as all actinides are radioactive and will trigger damage once internalized by the human body. The biological chemistry of actinide metal ions is largely unknown and new approaches to the understanding of pathways underlying contamination are needed. This work identifies a new mammalian pathway for the intracellular delivery of the radioactive toxic metal ions that are actinides, through the protein siderocalin. Spectroscopic tools, including X-ray diffraction and luminescence, provided insights on the coordination of these metal ions, which is crucial to devise new strategies for decontamination." @default.
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- W2156874308 date "2015-08-03" @default.
- W2156874308 modified "2023-10-18" @default.
- W2156874308 title "Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides" @default.
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- W2156874308 doi "https://doi.org/10.1073/pnas.1508902112" @default.
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