FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156880866> ?p ?o ?g. }

• W2156880866 endingPage "523" @default.
• W2156880866 startingPage "515" @default.
• W2156880866 abstract "This study aimed to determine the effect of insulin-like growth factor-I (IGF-I) on early antral bovine follicular development, and the expression of insulin-like growth factor-binding protein-2 (IGFBP-2). Antral follicles separated into three different size groups were cultured for 6 days in medium supplemented with either a low (10 ng/ml) or high (1 μg/ml) dose of human recombinant IGF-I. Oestradiol production by follicles in all size ranges, cultured in the presence of the high concentration of IGF-I, significantly increased by day 6 ( P < 0.05). Follicles in the smallest size range, 165–215 μm, cultured in a high dose of IGF-I, were found to be significantly increased in size ( P < 0.01). Oocyte health of the largest follicles (281–380 μm) was significantly improved by the addition of IGF-I to the culture medium. mRNA expression of IGFBP-2 was decreased in the granulosa cells of follicles, size range 216–280 μm, cultured with a high dose of IGF-I ( P < 0.05). Granulosa cells ( P < 0.05) and oocytes ( P < 0.01) of the largest follicles (281–380 μm) showed a decrease in IGFBP-2 expression (protein) when cultured in the control and low-IGF-I treatment groups. Therefore, the response of a bovine follicle to IGF-I is both dose and stage dependent. This work supports a role for IGF-I in modulating somatic and germ-cell maturation and development in early antral follicles. Furthermore, the inverse relationship between the level of IGF-I stimulation and IGFBP-2 expression suggests a local regulatory system modulating IGF-I availability." @default.
• W2156880866 created "2016-06-24" @default.
• W2156880866 creator A5017416460 @default.
• W2156880866 creator A5034035627 @default.
• W2156880866 creator A5041561816 @default.
• W2156880866 creator A5076561635 @default.
• W2156880866 creator A5007895761 @default.
• W2156880866 date "2006-03-01" @default.
• W2156880866 modified "2023-09-23" @default.
• W2156880866 title "The effects of IGF-I on bovine follicle development and IGFBP-2 expression are dose and stage dependent" @default.
• W2156880866 cites W1966782418 @default.
• W2156880866 cites W1972481356 @default.
• W2156880866 cites W1979127741 @default.
• W2156880866 cites W1989449490 @default.
• W2156880866 cites W2006168671 @default.
• W2156880866 cites W2022632758 @default.
• W2156880866 cites W2027745473 @default.
• W2156880866 cites W2028192827 @default.
• W2156880866 cites W2035414103 @default.
• W2156880866 cites W2041616290 @default.
• W2156880866 cites W2045008042 @default.
• W2156880866 cites W2056043788 @default.
• W2156880866 cites W2057482820 @default.
• W2156880866 cites W2069805450 @default.
• W2156880866 cites W2072727926 @default.
• W2156880866 cites W2074585597 @default.
• W2156880866 cites W2078486422 @default.
• W2156880866 cites W2079519492 @default.
• W2156880866 cites W2082874604 @default.
• W2156880866 cites W2085860432 @default.
• W2156880866 cites W2094598916 @default.
• W2156880866 cites W2100480273 @default.
• W2156880866 cites W2106138862 @default.
• W2156880866 cites W2106403561 @default.
• W2156880866 cites W2108027775 @default.
• W2156880866 cites W2131593655 @default.
• W2156880866 cites W2136995130 @default.
• W2156880866 cites W2159411410 @default.
• W2156880866 cites W2161283874 @default.
• W2156880866 cites W2163992775 @default.
• W2156880866 cites W2165917193 @default.
• W2156880866 cites W2332230337 @default.
• W2156880866 cites W4230106543 @default.
• W2156880866 cites W4235908535 @default.
• W2156880866 cites W4237353368 @default.
• W2156880866 cites W4237536168 @default.
• W2156880866 cites W4238430448 @default.
• W2156880866 cites W4249697631 @default.
• W2156880866 cites W4254722502 @default.
• W2156880866 doi "https://doi.org/10.1530/rep.1.00682" @default.
• W2156880866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16514194" @default.
• W2156880866 hasPublicationYear "2006" @default.
• W2156880866 type Work @default.
• W2156880866 sameAs 2156880866 @default.
• W2156880866 citedByCount "51" @default.
• W2156880866 countsByYear W21568808662012 @default.
• W2156880866 countsByYear W21568808662013 @default.
• W2156880866 countsByYear W21568808662014 @default.
• W2156880866 countsByYear W21568808662015 @default.
• W2156880866 countsByYear W21568808662017 @default.
• W2156880866 countsByYear W21568808662018 @default.
• W2156880866 countsByYear W21568808662019 @default.
• W2156880866 countsByYear W21568808662020 @default.
• W2156880866 countsByYear W21568808662021 @default.
• W2156880866 countsByYear W21568808662022 @default.
• W2156880866 countsByYear W21568808662023 @default.
• W2156880866 crossrefType "journal-article" @default.
• W2156880866 hasAuthorship W2156880866A5007895761 @default.
• W2156880866 hasAuthorship W2156880866A5017416460 @default.
• W2156880866 hasAuthorship W2156880866A5034035627 @default.
• W2156880866 hasAuthorship W2156880866A5041561816 @default.
• W2156880866 hasAuthorship W2156880866A5076561635 @default.
• W2156880866 hasBestOaLocation W21568808661 @default.
• W2156880866 hasConcept C102570824 @default.
• W2156880866 hasConcept C126322002 @default.
• W2156880866 hasConcept C134018914 @default.
• W2156880866 hasConcept C142773365 @default.
• W2156880866 hasConcept C16685009 @default.
• W2156880866 hasConcept C170493617 @default.
• W2156880866 hasConcept C185592680 @default.
• W2156880866 hasConcept C187785154 @default.
• W2156880866 hasConcept C196843134 @default.
• W2156880866 hasConcept C2775960820 @default.
• W2156880866 hasConcept C2776690073 @default.
• W2156880866 hasConcept C2780536345 @default.
• W2156880866 hasConcept C2780689927 @default.
• W2156880866 hasConcept C5512455 @default.
• W2156880866 hasConcept C71924100 @default.
• W2156880866 hasConcept C86803240 @default.
• W2156880866 hasConcept C87073359 @default.
• W2156880866 hasConcept C95444343 @default.
• W2156880866 hasConceptScore W2156880866C102570824 @default.
• W2156880866 hasConceptScore W2156880866C126322002 @default.
• W2156880866 hasConceptScore W2156880866C134018914 @default.
• W2156880866 hasConceptScore W2156880866C142773365 @default.
• W2156880866 hasConceptScore W2156880866C16685009 @default.
• W2156880866 hasConceptScore W2156880866C170493617 @default.
• W2156880866 hasConceptScore W2156880866C185592680 @default.

• next