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- W2156883602 abstract "We have engineered an optical nanoconstruct composed of genome-depleted brome mosaic virus doped with indocyanine green (ICG), an FDA-approved near-infrared (NIR) chromophore. Constructs are highly monodispersed with standard deviation of ±3.8 nm from a mean diameter of 24.3 nm. They are physically stable and exhibit a high degree of optical stability at physiological temperature (37 °C). Using human bronchial epithelial cells, we demonstrate the effectiveness of the constructs for intracellular optical imaging in vitro, with greater than 90% cell viability after 3 h of incubation. These constructs may serve as a potentially nontoxic and multifunctional nanoplatform for site-specific deep-tissue optical imaging, and therapy of disease." @default.
- W2156883602 created "2016-06-24" @default.
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- W2156883602 date "2011-01-06" @default.
- W2156883602 modified "2023-10-17" @default.
- W2156883602 title "Optical Nano-Constructs Composed of Genome-Depleted <i>Brome Mosaic Virus </i>Doped with a Near Infrared Chromophore for Potential Biomedical Applications" @default.
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- W2156883602 doi "https://doi.org/10.1021/nn1028696" @default.
- W2156883602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21210643" @default.
- W2156883602 hasPublicationYear "2011" @default.
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