FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2156896013> ?p ?o ?g. }

• W2156896013 endingPage "e113759" @default.
• W2156896013 startingPage "e113759" @default.
• W2156896013 abstract "Many metabolic processes in plants are regulated by manganese (Mn) but limited information is available on the molecular mechanisms controlling cellular Mn homeostasis. In this study, a yeast assay was used to isolate and characterize two genes, MTP8.1 and MTP8.2, which encode membrane-bound proteins belonging to the cation diffusion facilitator (CDF) family in the cereal species barley (Hordeum vulgare). Transient expression in onion epidermal cells showed that MTP8.1 and MTP8.2 proteins fused to the green fluorescent protein (GFP) are localized to Golgi. When heterologously expressed in yeast, MTP8.1 and MTP8.2 were found to be Mn transporters catalysing Mn efflux in a similar manner as the Golgi localized endogenous yeast protein Pmr1p. The level of MTP8.1 transcripts in barley roots increased with external Mn supply ranging from deficiency to toxicity, while MTP8.2 transcripts decreased under the same conditions, indicating non-overlapping functions for the two genes. In barley leaves, the expression of both MTP8 genes declined in response to toxic Mn additions to the roots suggesting a role in ensuring proper delivery of Mn to Golgi. Based on the above we suggest that barley MTP8 proteins are involved in Mn loading to the Golgi apparatus and play a role in Mn homeostasis by delivering Mn to Mn-dependent enzymes and/or by facilitating Mn efflux via secretory vesicles. This study highlights the importance of MTP transporters in Mn homeostasis and is the first report of Golgi localized Mn2+ transport proteins in a monocot plant species." @default.
• W2156896013 created "2016-06-24" @default.
• W2156896013 creator A5008567312 @default.
• W2156896013 creator A5047902699 @default.
• W2156896013 creator A5055043461 @default.
• W2156896013 creator A5070395842 @default.
• W2156896013 creator A5085416485 @default.
• W2156896013 creator A5088628110 @default.
• W2156896013 date "2014-12-08" @default.
• W2156896013 modified "2023-10-10" @default.
• W2156896013 title "Golgi Localized Barley MTP8 Proteins Facilitate Mn Transport" @default.
• W2156896013 cites W1497947649 @default.
• W2156896013 cites W1589893269 @default.
• W2156896013 cites W1599093544 @default.
• W2156896013 cites W1628013791 @default.
• W2156896013 cites W1787240576 @default.
• W2156896013 cites W1839658873 @default.
• W2156896013 cites W1907426129 @default.
• W2156896013 cites W1934739975 @default.
• W2156896013 cites W1965570914 @default.
• W2156896013 cites W1970630357 @default.
• W2156896013 cites W1978795274 @default.
• W2156896013 cites W1979250425 @default.
• W2156896013 cites W1979957368 @default.
• W2156896013 cites W1981519049 @default.
• W2156896013 cites W1992153139 @default.
• W2156896013 cites W2007646864 @default.
• W2156896013 cites W2015061479 @default.
• W2156896013 cites W2025377723 @default.
• W2156896013 cites W2038800117 @default.
• W2156896013 cites W2044157062 @default.
• W2156896013 cites W2055277664 @default.
• W2156896013 cites W2060687391 @default.
• W2156896013 cites W2066015779 @default.
• W2156896013 cites W2067073603 @default.
• W2156896013 cites W2078762450 @default.
• W2156896013 cites W2089824746 @default.
• W2156896013 cites W2092555654 @default.
• W2156896013 cites W2094627126 @default.
• W2156896013 cites W2097174216 @default.
• W2156896013 cites W2097268562 @default.
• W2156896013 cites W2097568732 @default.
• W2156896013 cites W2102544942 @default.
• W2156896013 cites W2102965416 @default.
• W2156896013 cites W2107782434 @default.
• W2156896013 cites W2108053853 @default.
• W2156896013 cites W2108244474 @default.
• W2156896013 cites W2108600573 @default.
• W2156896013 cites W2108791511 @default.
• W2156896013 cites W2113786433 @default.
• W2156896013 cites W2119012317 @default.
• W2156896013 cites W2120332316 @default.
• W2156896013 cites W2123738381 @default.
• W2156896013 cites W2124946184 @default.
• W2156896013 cites W2125121305 @default.
• W2156896013 cites W2126147905 @default.
• W2156896013 cites W2126742458 @default.
• W2156896013 cites W2132519271 @default.
• W2156896013 cites W2133733060 @default.
• W2156896013 cites W2140948740 @default.
• W2156896013 cites W2141082893 @default.
• W2156896013 cites W2152613471 @default.
• W2156896013 cites W2156442455 @default.
• W2156896013 cites W2163169780 @default.
• W2156896013 cites W2165473897 @default.
• W2156896013 cites W2165622051 @default.
• W2156896013 cites W2227108503 @default.
• W2156896013 cites W2398832653 @default.
• W2156896013 cites W4230151378 @default.
• W2156896013 cites W4240065971 @default.
• W2156896013 cites W4244729944 @default.
• W2156896013 cites W4247734158 @default.
• W2156896013 doi "https://doi.org/10.1371/journal.pone.0113759" @default.
• W2156896013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4259309" @default.
• W2156896013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25486417" @default.
• W2156896013 hasPublicationYear "2014" @default.
• W2156896013 type Work @default.
• W2156896013 sameAs 2156896013 @default.
• W2156896013 citedByCount "60" @default.
• W2156896013 countsByYear W21568960132015 @default.
• W2156896013 countsByYear W21568960132016 @default.
• W2156896013 countsByYear W21568960132017 @default.
• W2156896013 countsByYear W21568960132018 @default.
• W2156896013 countsByYear W21568960132019 @default.
• W2156896013 countsByYear W21568960132020 @default.
• W2156896013 countsByYear W21568960132021 @default.
• W2156896013 countsByYear W21568960132022 @default.
• W2156896013 countsByYear W21568960132023 @default.
• W2156896013 crossrefType "journal-article" @default.
• W2156896013 hasAuthorship W2156896013A5008567312 @default.
• W2156896013 hasAuthorship W2156896013A5047902699 @default.
• W2156896013 hasAuthorship W2156896013A5055043461 @default.
• W2156896013 hasAuthorship W2156896013A5070395842 @default.
• W2156896013 hasAuthorship W2156896013A5085416485 @default.
• W2156896013 hasAuthorship W2156896013A5088628110 @default.
• W2156896013 hasBestOaLocation W21568960131 @default.
• W2156896013 hasConcept C119062480 @default.
• W2156896013 hasConcept C158617107 @default.

• next